Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$125K *

Transform the future of mobile development by leveraging AI to enhance marketplace experiences. Collaborate with cross-functional teams to design, build, and ship high-quality Android applications tha...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Transportation

$132K - $155K *

Empower enterprises to modernize data ecosystems by architecting scalable solutions that enhance data accessibility and quality, driving measurable business value through collaboration and innovative...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Shape the future of embedded systems engineering by leading a high-performance team, defining technical roadmaps, and integrating AI-driven workflows to deliver innovative, reliable solutions across d...

RemoteRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$150K - $180K *

Lead and scale a dynamic engineering organization, driving execution and innovation while mentoring managers and aligning cross-functional priorities to deliver impactful solutions...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Drive quality assurance for ICT cabling infrastructure across 700+ Army Reserve sites. Collaborate with engineering teams and contractors to ensure compliance with technical standards and deliver exce...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform the future of data center commissioning by leading controls installation verification, driving automation, and ensuring quality across multiple projects while coordinating with teams to meet...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$98K - $206K *

Unlock the potential of data engineering by automating cloud data ingestion and transformation processes. Utilize cutting-edge AWS services to ensure reliability and performance in a mission-driven en...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Engage with clients to enhance their cybersecurity resilience by leading incident response efforts, providing expert guidance, and preparing detailed reports to mitigate risks and improve security pos...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $120K *

Take ownership of client onboarding by guiding users through configuration, data migration, and training while collaborating across teams to ensure seamless implementation and long-term partnership su...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $157K *

Shape the future of enterprise sales by driving innovative strategies, fostering relationships, and generating revenue through a proactive approach in a dynamic, remote environment focused on large mu...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$100K - $120K *

Champion strategic initiatives by leading account management and operational excellence. Drive program deployment, enhance client relationships, and ensure team performance to exceed expectations whil...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $145K *

Unlock potential by bridging IT policy and strategy with organizational goals. Manage policy governance for a federal CIO organization, ensuring alignment with federal standards and overseeing a compr...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Engineer customer reliability by providing expert technical support for IoT solutions. Collaborate with teams to resolve issues, enhance documentation, and gather feedback, ensuring a seamless custome...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$95K *

Join a team that's driving growth by managing key Integrator accounts, developing sales strategies, and fostering relationships to exceed corporate goals in the material handling industry...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $120K *

Champion hardware readiness for customer deployments, ensuring timely delivery and accurate documentation. Collaborate with cross-functional teams to manage escalations, RMAs, and configuration contro...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$189K - $231K *

Innovate and shape the future of AI platforms as a Senior Engineer, designing and building critical subsystems for enterprise Kubernetes environments. Collaborate with customers and mentor engineers t...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$300K - $500K *

Champion innovation by architecting and developing high-performance, real-time trading web apps. Leverage your expertise to enhance user experience and drive product evolution in a dynamic, collaborat...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Empower quality assurance excellence by leading inspections across North America, ensuring critical infrastructure meets project standards. Collaborate with suppliers and teams to mitigate risks and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$170K - $185K *

Drive impactful IT program initiatives for Federal and SLED Governments, overseeing planning, execution, and financial management while fostering client relationships and identifying growth opportunit...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$137K - $231K *

Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Empower our mission by leading data center and cloud engineering strategies. This hands-on role requires expertise in infrastructure planning, hybrid-cloud architecture, and automation to drive modern...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$80K - $92K *

Drive the resolution of technical support escalations as a key Tier 2 expert, leveraging your skills to troubleshoot issues, foster collaboration within teams, and enhance workflows in a dynamic envir...

RemoteRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Technical Services

$85K - $130K *

Champion innovative control systems for industrial solutions, leading design and development projects. Collaborate with teams to ensure products meet market demands while transitioning designs to manu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$100K - $122K *

Join a team that's redefining DevOps by building and maintaining CI/CD pipelines, automating workflows, and enhancing service delivery in AWS. Collaborate with cross-functional teams to ensure reliabl...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.