Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.
High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.
Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.
Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.
Principal AI Solutions Architect
$220K - $310K *
Empower businesses by architecting and deploying innovative AI solutions that leverage graph databases and LLMs. Collaborate with stakeholders to transform complex data challenges into impactful appli...
6 days ago
Senior Engineer, Data Engineering
$144K - $165K *
Unlock potential by owning data architecture and reliability across domains. Collaborate with an AI-first team to design robust data pipelines, enhance analytics, and drive impactful solutions in a dy...
1 week ago
$83K - $118K *
Unlock your potential by leading complex IT/SaaS projects, driving execution, and enhancing business processes. Collaborate with diverse teams to ensure project success while utilizing Agile methodolo...
4 weeks ago
$143K - $179K *
Analyze customer experiences to drive retention strategies and enhance satisfaction. Collaborate across teams to shape data-driven decisions, develop metrics, and prioritize analytics initiatives that...
2 days ago
Senior Infrastructure Engineer- Secure Developer Platforms (Azure/VDI)
$125K - $150K *
Lead the charge in building a secure, self-service developer sandbox on Azure, delivering non-persistent desktops and managing the entire stack from landing zone to golden image while ensuring complia...
2 weeks ago
Lead Solution Architect, Physical AI
$140K - $175K *
Transform the landscape of Physical AI by leading technical design and delivery of innovative systems that integrate computer vision, robotics, and digital twin technologies, ensuring seamless operati...
3 weeks ago
$208K - $229K *
Join a team that's shaping innovative Salesforce solutions! As a Senior Solution Architect, you'll design technical solutions, guide project teams, and enhance client satisfaction while driving growth...
Today
$135K - $160K *
Champion modernization initiatives by designing and overseeing transformation solutions, integrating cutting-edge GenAI technology, and ensuring alignment with business objectives to drive impactful m...
Reposted 3 weeks ago
$100K - $120K *
Lead the charge in enhancing security for a complex federal platform, safeguarding cloud infrastructure and sensitive data. Collaborate within an Agile team to design, implement, and automate robust s...
3 weeks ago
Lead Consultant - Network Security
$98K - $167K *
Innovate within our network security team by leading the engineering and automation of enterprise security platforms. Drive technical excellence and enhance infrastructure management through modern pr...
2 weeks ago
F5 Advanced Web Application Firewall Engineer
$108K - $130K *
Transform enterprise web application security by engineering and managing F5 WAF policies. Collaborate with cybersecurity teams to enhance protection, tune policies, and respond to incidents, ensuring...
Today
Oracle Fusion Financial Architect
$98K - $206K *
Bring your expertise to architect solutions in Oracle Fusion Financials, enhancing federal financial operations for military logistics. Lead design efforts to ensure compliance and data integrity acro...
Reposted 2 weeks ago
Mainframe Systems Programmer - Network
$65K - $126K *
Join a team that's dedicated to optimizing mainframe network systems. Leverage your expertise in planning, installing, and maintaining software while ensuring system performance and reliability. Colla...
3 weeks ago
$95K - $100K *
Optimize enterprise secrets management by implementing and maintaining solutions across multi-cloud environments. Collaborate with teams to integrate security processes, enhance governance, and suppor...
Yesterday
Program Manager (Data Center Hardware)
$145K - $155K *
Transform customer engagements by leading a dynamic team, ensuring project success through effective management and operational oversight. Drive continuous improvement and enhance client satisfaction...
Yesterday
SAP Senior Solution Architect, Manufacturing
$150K - $232K *
Lead transformative SAP solutions in manufacturing, optimizing processes and driving innovation. Collaborate with teams to deliver value-driven results, leveraging deep expertise in SAP S/4HANA and bu...
1 week ago
Network and Systems Engineer III – IT Solutions Implementor
$110K - $132K *
Innovate IT solutions by evaluating project requirements, providing technical support, and maintaining network infrastructure. Collaborate with teams globally to ensure seamless operations and enhance...
2 days ago
Technical Enablement Manager, Identity Security
$130K - $160K *
Join a team that's shaping the future of identity security by developing impactful enablement programs for pre-sales teams. Collaborate with cross-functional leaders to enhance skills and drive busine...
3 weeks ago
Staff AI Engineer, Agentic Automation
$150K - $180K *
Help us drive the future of automation by owning AI agents that onboard applications and ensure self-healing workflows. You'll enhance existing systems, prioritize security, and collaborate across tea...
1 week ago
Acoustics Engineer, Capacity Delivery
$100K - $120K *
Innovate noise control solutions for large-scale AI data centers. Lead acoustic studies, model sound propagation, and recommend effective mitigations while collaborating across engineering teams to en...
Reposted yesterday
$150K - $180K *
Lead the charge in enhancing engineering security for our SaaS platform. Collaborate with teams to identify risks, improve practices, and implement automation, ensuring secure development and robust v...
6 days ago
Senior Computer Systems Engineer/Architect - Informatica
$170K - $210K *
Lead the design and implementation of cross-platform solutions in AWS GovCloud, focusing on Informatica architecture, security, and CI/CD practices. Collaborate with multidisciplinary teams to ensure...
1 week ago
$218K - $256K *
Lead the charge in shaping IT strategy and operations for a remote-first SaaS company. Drive service delivery, enhance employee technology experiences, and build a high-performing IT organization whil...
3 weeks ago
$90K - $110K *
Lead the charge in delivering innovative managed services solutions by partnering with sales teams to assess client needs, design scalable architectures, and ensure seamless transitions, driving long...
6 days ago
$150K - $180K *
Champion enterprise systems diligence and value creation engagements, assessing technology, processes, and infrastructure to drive operational excellence and strategic insights for investors and manag...
2 weeks ago
What types of $100,000+ jobs can I find in Mississippi?
Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.
Which Mississippi cities have high-paying job opportunities?
Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.
Are remote jobs available to Mississippi residents?
Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.
How can I qualify for a $100,000+ job in Mississippi?
Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.