Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with salaries of $100,000 or more. Ladders features vetted roles for experienced candidates seeking senior-level careers across the Magnolia State, from Jackson and the Gulf Coast to regional business hubs.

Mississippi Careers Across Industries

High-paying opportunities may be available in healthcare, technology, manufacturing, finance, energy, engineering, and executive leadership. Job availability and requirements vary by employer, location, and experience level, so review each listing for details.

Find Opportunities by Location

Search roles in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other Mississippi communities. You can also consider remote and hybrid positions with employers hiring professionals based in the state.

How to Search Mississippi Jobs on Ladders

Explore current listings, compare responsibilities and compensation details, and focus your search on roles that match your skills and career goals. Tailor your résumé to highlight measurable results, leadership experience, and relevant expertise when applying.

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$166K - $200K *

Lead impactful solutions as a Global Solution Architect, driving business value through strategic customer engagement and technical expertise. Collaborate with sales teams to architect innovative auto...

RemoteRemote

2 weeks ago

  •   15+ years exp.  •   Manufacturing & Automotive

$95K - $115K *

Elevate data center operations by coordinating service delivery and ensuring compliance with security standards. Lead hybrid cloud initiatives, optimize performance, and collaborate with teams to enha...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Oversee governance and performance of Data Center Services, ensuring operational excellence and compliance across on-premises and hybrid cloud environments while driving continuous improvement and ali...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$128K - $193K *

Drive successful Microsoft 365 Managed Services engagements by overseeing technical delivery, maintaining client relationships, and providing expert guidance on complex solutions to ensure client sati...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Engage in designing and implementing robust cybersecurity solutions while managing security technologies and cloud services. Collaborate across teams to ensure operational performance and support clie...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Shape the future of electrical engineering by collaborating with design teams, ensuring technical compliance, and enhancing performance across diverse projects. Join us to tackle innovative challenges...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $127K *

Elevate your career by supporting the design and maintenance of enterprise WAN infrastructure. Collaborate with diverse teams to ensure network reliability and performance across multiple locations, e...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Elevate your career by designing and delivering innovative video solutions across diverse sectors. Collaborate with teams to create scalable architectures that enhance broadcast, streaming, and cloud...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$124K - $187K *

Join a dynamic team to define and guide technical direction across platforms, ensuring scalable, secure solutions that align with business outcomes. Collaborate with cross-functional teams to resolve...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Drive impactful solutions by maintaining and developing Finance and Procurement systems. Collaborate with teams to analyze requirements, debug SQL queries, and enhance application performance for a se...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$100K - $145K *

Join a dynamic team to ensure seamless network connectivity for dock deployments. Collaborate with IT teams, troubleshoot connectivity issues, and enhance customer confidence through effective communi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$320K - $405K *

Engineer cutting-edge protection and automation systems for high-voltage substations, ensuring reliable power distribution and integration across our infrastructure portfolio. Collaborate with teams t...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $165K *

Join a dynamic team to design and implement robust cloud security solutions across diverse environments, ensuring safe adoption of AI and compliance with regulatory standards while leading technical i...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Technical Services

$80K - $95K *

Elevate your career by partnering with us to optimize enterprise network performance. You'll troubleshoot complex issues, collaborate with cross-functional teams, and drive improvements to ensure secu...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $100K *

Lead the charge in enhancing cybersecurity by executing offensive strategies, identifying vulnerabilities, and collaborating across teams to ensure robust protection against evolving threats. Embrace...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$135K - $160K *

Advance security integration by leading DevSecOps initiatives, enhancing software delivery, and establishing robust security standards across engineering teams to mitigate risks and improve efficiency...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Empower innovation as you design complex electrical systems, lead projects, mentor teams, and ensure high-quality deliverables. Collaborate closely with multi-disciplinary teams, utilizing advanced BI...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$156K - $281K *

Drive innovative solutions by leading complex Federal acquisitions, guiding cross-functional teams, and delivering high-quality proposals. Leverage technical expertise to elevate win probability and e...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$95K - $130K *

Manage the design and implementation of integrated physical security systems, driving innovative solutions in complex environments while fostering collaboration with clients and stakeholders for enhan...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$140K - $175K *

Develop innovative software solutions that enhance access to mental and physical health services. Collaborate with cross-functional teams to deliver reliable applications, ensuring quality and perform...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$107K - $150K *

Transform the security landscape by implementing and supporting cutting-edge physical security systems, ensuring client satisfaction and seamless integration for improved safety and network efficiency...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Information Technology

$150K - $180K *

Transform the architecture of diverse security platforms, guiding teams through complex design challenges while ensuring scalable, secure, and maintainable systems across multiple product areas in a h...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Innovate enterprise architecture solutions that enhance business operations. Collaborate with IT and business teams to tackle complex challenges, ensuring scalable, secure, and efficient systems acros...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$90K - $120K *

Elevate your career by leading clients through the CMMC 2.0 compliance journey. As a key advisor, you'll translate complex regulations into actionable strategies, ensuring audit readiness and security...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $185K *

Unlock business growth by leading technical scoping, managing client relations, and guiding consultants. This hybrid role integrates project management with hands-on consulting to ensure accurate prop...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Mississippi?question toggle

    Listings may include senior roles in healthcare, technology, manufacturing, finance, energy, engineering, and management. Opportunities change over time, so check current listings for available positions.

  • Which Mississippi cities have high-paying job opportunities?question toggle

    Professional opportunities may be listed in Jackson, Gulfport, Biloxi, Hattiesburg, Southaven, and other parts of the state, depending on employer hiring needs.

  • Are remote jobs available to Mississippi residents?question toggle

    Some employers offer remote or hybrid positions that may be open to Mississippi-based candidates. Review each listing to confirm location and work arrangement requirements.

  • How can I qualify for a $100,000+ job in Mississippi?question toggle

    Requirements vary by role. Employers commonly seek relevant experience, specialized skills, and a record of strong results; senior positions may also require leadership experience or advanced credentials.