Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$86K - $165K *

Lead the charge in developing advanced navigation systems for military applications. Collaborate with cross-functional teams to ensure system requirements are met, while driving innovation and problem...

4 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$180K - $240K *

Elevate your career by designing and building robust distributed systems. Lead architectural decisions, ensure reliability, and mentor engineers while tackling complex challenges in regulated environm...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Shape the future of clinical trials by driving business development initiatives, identifying opportunities with sponsors and CROs, and promoting CTSdatabase's services to enhance growth and profitabil...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $293K *

Join a team that's transforming data engineering for AI. Lead modernization efforts with batch and streaming pipelines, ensuring data governance and quality for trusted AI consumption. Travel may vary...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Champion strategic partnerships and drive revenue growth through effective channel management and collaborative business planning, ensuring sales success and partner satisfaction while navigating comp...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$80K - $95K *

Transform customer data integration by configuring and validating mappings between third-party systems and applications. Collaborate with teams to ensure seamless onboarding and ongoing support, enhan...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$98K - $163K *

Shape your career by providing Tier III IT Systems support across enterprise technologies. Collaborate on projects, resolve complex challenges, and mentor junior engineers while ensuring operational e...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$163K - $413K *

Lead the charge in driving strategic partnerships and sales growth in cybersecurity, leveraging deep industry expertise and executive relationships to enhance global market presence and deliver innova...

1 week ago

  •   11 - 15 years exp.  •   Business Services

$172K - $202K *

Lead the charge in delivering expert guidance on identity and access management technologies, focusing on architecting solutions and producing actionable research to enhance client performance and sec...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$90K - $125K *

Lead the development and submission of federal proposals, managing teams and resources to deliver compliant, compelling responses. Collaborate with cross-functional teams to ensure alignment with cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$120K - $144K *

Optimize large-scale building automation projects by leading cross-functional teams, managing budgets, and ensuring client satisfaction. Drive innovative strategies for execution and risk management i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$94K - $266K *

Join us to lead innovative cloud-based contact center projects, driving success for Mid-Market & Enterprise clients. Utilize your project management expertise to deliver cutting-edge solutions and fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$200K - $285K *

Champion innovation by leading technical strategy and open standards initiatives, driving interoperability in payments and protocol architecture while collaborating with diverse stakeholders to enhanc...

RemoteRemote

2 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$74K - $112K *

Innovate within our drive strategy team by developing embedded software that enhances agricultural efficiency and productivity. Collaborate with cross-functional teams to deliver high-impact solutions...

3 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in building and scaling strategic partnerships to drive revenue growth. Oversee the entire partner lifecycle, from selection to enablement, ensuring successful collaboration and measur...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $270K *

Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $200K *

Drive global mechanical category strategy for advanced thermal management systems, ensuring optimal cost, quality, and reliability across a diverse supplier ecosystem while supporting scalable data ce...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $150K *

Advance cloud infrastructure by designing, deploying, and managing scalable solutions. Collaborate with teams to ensure compliance, optimize costs, and enhance operational efficiency while supporting...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $180K *

Unlock the potential of Army logistics by driving enterprise architecture, cybersecurity, and systems integration initiatives. Collaborate with stakeholders to enhance business processes and deliver i...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Join a team that's redefining healthcare solutions by leading technical demos and driving enterprise sales. Collaborate with executives to translate needs into impactful presentations, ensuring succes...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $161K *

Lead the charge in deploying and scaling enterprise AI solutions, ensuring secure and effective adoption. Collaborate with cross-functional teams to transform client needs into practical AI applicatio...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $161K *

Unlock potential by deploying and supporting enterprise AI solutions, enhancing client readiness, and driving adoption through hands-on consulting and collaboration with cross-functional teams to ensu...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $120K *

Contribute to customer success by developing technical expertise across platforms, integrations, and operational processes. Collaborate with teams to resolve issues and enhance solutions, while gainin...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to enhancing enterprise IAM governance. You'll oversee access reviews, ensure compliance, and collaborate with cross-functional teams to strengthen security controls and d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.