Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$120K - $145K *

Drive innovative solutions by architecting complex enterprise technologies for federal healthcare, focusing on VA and other agencies. Collaborate across teams to translate requirements into scalable...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $180K *

Innovate with us as you lead technical delivery for enterprise data integration and migration projects, focusing on Higher Education and Salesforce ecosystems. Drive solution architecture, manage team...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Inspire growth by leading strategic initiatives for key telecom accounts, fostering executive relationships, and driving multi-year revenue plans. Collaborate across teams to align solutions with evol...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Transportation

$140K - $160K *

Drive the development of critical enterprise applications for DoD personnel, enhancing program and financial management capabilities. Collaborate within a product team to modernize technology and deli...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$94K - $120K *

Lead the charge in delivering impactful IT projects by managing all phases from initiation to closeout. Collaborate with diverse teams to ensure timely and successful project execution while aligning...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$200K - $383K *

Join a team that's redefining internal audit excellence. Lead strategic initiatives, enhance risk management, and drive compliance while leveraging cutting-edge technologies to optimize processes and...

United StatesRemote

2 days ago

  •   15+ years exp.  •   Real Estate & Construction

$88K - $105K *

Empower data-driven decisions by developing and maintaining robust data infrastructure. Collaborate with cross-functional teams to ensure data integrity, security, and accessibility, while driving inn...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$148K - $256K *

Shape the future of data engineering by architecting scalable, cloud-native data platforms on Azure and Databricks. Influence the organization’s data practices to leverage AI-driven insights, driving...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform aerospace navigation systems by collaborating in Agile teams to develop, test, and validate software solutions. Engage in a dynamic environment focused on compliance and innovation, contribu...

Today

  •   Less than 5 years exp.  •   Information Technology

$132K - $176K *

Drive market growth by developing strategic partnerships and solutions. Collaborate with teams to enhance customer engagement and competitive positioning, ensuring alignment with long-term objectives...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$163K - $203K *

Elevate security standards by leading classified design and accreditation for defense facilities. Collaborate with cross-functional teams to ensure compliance and streamline processes for rapid deploy...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$90K - $110K *

Engage with clients, driving success in digital campaign execution. Become an expert in programmatic advertising processes, enhancing customer satisfaction through effective communication and collabor...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$192K - $278K *

Lead and grow a high-performing engineering team responsible for the reliability and scalability of critical data systems. Drive architectural decisions, incident response, and team development while...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$150K - $175K *

Shape the cloud infrastructure landscape by ensuring security, scalability, and efficiency. Collaborate with engineers to build resilient systems and drive best practices, enabling smooth deployment a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $111K *

Take ownership of Oracle EBS Project Accounting operations, enhancing project costing, billing, and financial processes. Collaborate with diverse teams to document workflows and improve operational re...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$90K - $120K *

Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $206K *

Champion innovative solutions as a Senior Full Stack Software Developer, driving the development of web and mobile applications for U.S. Navy Reserve systems. Collaborate with cross-functional teams t...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$114K - $171K *

Join a dynamic team as a technical leader, guiding software development while mentoring talent. Drive innovation in web applications using modern frameworks, enhance team performance, and collaborate...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $220K *

Unlock potential by joining a dynamic security team to enhance cloud and application security, ensuring compliance and fostering a secure culture across all functions while leveraging cutting-edge tec...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$124K - $187K *

Shape your career by leading the design and operation of AI and ML systems. Collaborate across teams to establish architecture standards, optimize workflows, and ensure operational readiness for innov...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Information Technology

$140K - $210K *

Lead the charge in delivering innovative integration solutions for clients in the State & Local Government sector. Collaborate with project teams to design, develop, and implement effective Workday in...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$120K *

Lead the charge in securing AI applications by building robust defenses and controls across our core security platforms. This hands-on role involves engineering, deploying, and operating security meas...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Empower our cybersecurity initiatives by providing strategic leadership and ensuring compliance with DoD standards. Drive enterprise-level security architecture and risk management across multiple Tas...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$138K - $173K *

Drive cross-functional collaboration to ensure high-quality software delivery. Lead and mentor a team of engineers while optimizing processes and fostering a culture of innovation and continuous impro...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Grow enterprise SAP relationships by managing key accounts and driving new business. Leverage your expertise to expand client portfolios, develop strategic plans, and ensure client satisfaction while...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.