Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$150K - $180K *

Empower innovation by architecting next-gen AI-driven CRM solutions. Lead a dynamic team to optimize data processing, enhance automation, and deliver exceptional user experiences while driving market...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$70K - $105K *

Optimize provisioning strategies for mission-critical SATCOM systems. Collaborate with cross-functional teams to ensure operational readiness and minimize downtime through effective logistics support...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $170K *

Transform business growth by developing strategic partnerships and driving sales in IT infrastructure. Leverage your expertise to build relationships, conduct market analysis, and exceed revenue targe...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Empower your career by leading data architecture initiatives across Oracle Cloud applications. Drive data governance, migration, and integration strategies to enhance business processes and ensure dat...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Staffing

$297K - $367K *

Grow your career with a pivotal role driving hospital data integration and compliance. Lead execution of clinical data operations, build relationships, and ensure secure data handling while shaping a...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Drive the development of innovative AI and data solutions, enhancing enterprise data platforms while ensuring scalable, quality delivery. Collaborate with teams to define technical architecture, shapi...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$115K - $130K *

Join a dynamic team as you provide essential IT support to a distributed workforce. Leverage your troubleshooting skills to resolve technical issues, enhance user experience, and contribute to a colla...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Join a team that's passionate about security innovation, focusing on penetration testing and threat modeling across diverse technologies. Leverage your expertise in software and hardware analysis to t...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$170K - $220K *

Drive your career forward by leading cross-functional deployment strategies. This senior role requires exceptional judgment and communication skills to navigate complex, ambiguous situations and deliv...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$95K - $115K *

Lead the charge in designing and optimizing scalable data pipelines and infrastructure, ensuring efficient data processing and delivery to support agency missions. Collaborate with cross-functional te...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Drive your career with a role focused on designing and optimizing data pipelines and infrastructure. Collaborate with cross-functional teams to enhance data delivery and support the agency's mission t...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform cybersecurity practices by leading vulnerability management and penetration testing efforts. Collaborate with cross-functional teams to enhance security controls, reduce risks, and ensure ro...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Champion security excellence by leading complex Microsoft Sentinel and Defender XDR implementations. Drive technical enablement projects, mentor engineers, and enhance client security practices in a d...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by designing and managing Azure infrastructure, ensuring seamless hybrid connectivity and robust disaster recovery. Collaborate across teams to enhance operations, automate processes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$140K - $160K *

Accelerate progress at our integration platforms, ensuring scalable, reliable data flows. You'll design, build, and optimize workflows while collaborating across teams to enhance performance and custo...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Unlock your potential as you support impactful traffic and ITS projects, collaborating with a dynamic team to deliver high-quality engineering solutions that shape communities across the Midwest and S...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$74K - $87K *

Transform client implementations by leading discovery, planning, and execution. Own project scope, timelines, and budgets to ensure successful adoption of solutions that align with business goals and...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Information Technology

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$144K - $200K *

Unlock potential by managing end-to-end technical deployments of computer vision systems. Collaborate with clients in diverse environments to ensure seamless production operations and enhance system p...

United StatesRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Staffing

$165K - $260K *

Drive the development of an intelligent content delivery network, optimizing web performance through cutting-edge infrastructure and AI. Collaborate with a lean team to transform complex problems into...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$114K - $143K *

Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $97K *

Shape the future of digital experiences by delivering innovative web solutions that enhance member engagement and drive growth. Collaborate with cross-functional teams to create intuitive, high-qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $170K *

Join a dynamic team to optimize operational systems, drive growth, and enhance performance across departments. Collaborate with leadership to ensure strategic goals translate into measurable results a...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $212K *

Pioneer innovative IAM strategies to enhance security across cloud and on-premise infrastructures. Collaborate with cross-functional teams to implement robust identity governance and access management...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$207K - $290K *

Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.