Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

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With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

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Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

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1
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$151K - $216K *

Unlock your potential by leading a dynamic engineering team to deliver innovative solutions, drive technical excellence, and foster collaboration while serving the U.S. Government in a hybrid work env...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$134K - $205K *

Join our team to optimize nuclear power output through advanced engineering solutions. Leverage your technical expertise in thermodynamics and power plant processes to support major projects and mento...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$120K - $145K *

Elevate your career by leading cybersecurity governance and compliance efforts. Oversee information assurance processes while collaborating with diverse teams to secure mission-critical operations in...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$152K - $287K *

Join a team that's building scalable infrastructure for critical EDA workloads, improving reliability and automation for high-performance computing environments. Leverage your programming skills and e...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$103K - $181K *

Lead the charge in ensuring industrial control systems operate safely and effectively, collaborating across teams to validate control strategies and support government defense projects through compreh...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$134K - $241K *

Take ownership of a major federal program's construction management services, leading critical activities including oversight, safety, quality assurance, and stakeholder coordination to ensure project...

US-AnywhereRemote

1 week ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$124K - $170K *

Join a team that's shaping the future of cybersecurity in healthcare by leading assurance activities, managing risks, and championing compliance throughout the product life cycle while collaborating w...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$170K - $240K *

Drive engineering excellence and operational performance across enterprise-level functions by leading strategic initiatives, optimizing processes, and influencing cross-functional planning as a senior...

US-AnywhereRemote

2 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$174K - $305K *

Innovate and lead the development of autonomous software systems. Collaborate with cross-functional teams to enhance vehicle safety and performance while mentoring engineers and driving technical visi...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $178K *

Pioneer a comprehensive Computer System Validation strategy across GxP systems. Collaborate with Quality and IT to drive compliance and data integrity while enhancing efficiency in validation processe...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$164K - $207K *

Elevate your career by designing, building, and scaling innovative AI and ML solutions across cloud environments, impacting biomedical research and operational efficiency through advanced data-driven...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$75K - $90K *

Unlock potential by joining a dynamic team focused on delivering tailored solutions. Leverage your sales expertise and strong relationships to drive results and enhance client satisfaction in a collab...

US-AnywhereRemote

3 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$108K - $221K *

Shape the future of government technology as a senior advisor directing modernization efforts across enterprise infrastructure, cloud, cybersecurity, and more. Collaborate with key stakeholders to enh...

US-AnywhereRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$72K - $115K *

Elevate your career as a Network Engineer II. Support and manage our network infrastructure while troubleshooting issues and ensuring effective communication for a seamless production experience. Join...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Join a team that's at the forefront of OpenBMC firmware development, driving platform bring-up, feature implementation, and integration to enhance system functionality and reliability. Contribute your...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$90K - $100K *

Help us drive strategic initiatives within Navy housing programs. You will support the planning and execution of barracks improvements, collaborating with stakeholders to enhance housing conditions, r...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$150K - $155K *

Champion program delivery for an enterprise data platform, managing scope, schedule, and risk. Engage with government stakeholders while enabling Agile teams for successful execution and ensuring qual...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Oversee the administration of cloud-based IT systems, driving service quality and efficiency while managing escalated support and strategic IT projects for a dynamic organization poised for growth...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$77K - $119K *

Elevate your expertise by building and enhancing a clinical data repository, leading projects, and analyzing business needs within emerging technologies to optimize healthcare data management solution...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $163K *

Shape the future of cybersecurity by leading innovative approaches to protect connected medical devices and IT systems. Drive compliance and enhance patient safety while mentoring a team in this criti...

US-AnywhereRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$165K - $236K *

Join a team that's dedicated to enhancing federal networks by driving technical sales and support. Leverage your networking expertise in pre-sales and post-sales, educating clients on advanced securit...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$148K - $235K *

Elevate your career as you design and deploy cutting-edge networking solutions, fundamentally shaping the performance of AI workloads in large clusters through collaboration with customers and R&D tea...

US-AnywhereRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$95K - $115K *

Join a team that's dedicated to driving healthcare innovation through exceptional laboratory sales expertise. Collaborate with professionals to expand our Specialty Diagnostics portfolio and enhance c...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$145K - $155K *

Join our team as a Program Manager, leading strategic technology programs that drive business value. Collaborate cross-functionally to ensure project alignment and operational excellence while mentori...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$139K - $201K *

Accelerate product innovation by leading the development of data pipelines, defining the vision and strategy for customer-centric solutions that enhance data processing across platforms, ensuring alig...

US-AnywhereRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.