Mission Systems Engineer Jobs

At Ladders, we connect you with the best available Mission Systems Engineering jobs that pay over $100,000 a year. Mission Systems Engineers play an essential role in the development, operation, and application of both hardware and software systems in aerospace and defense sectors.

Find Your Next Opportunity

With listings from a wide variety of industries, you can find a position that fits your unique skill set. Quality assured with vetted opportunities from leading companies.

Rise Above With Superior Positions

Aim for the stars with high salaried jobs in Mission Systems Engineering. Leverage your expertise to land a six-figure job that matches your career goals.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
More
1
caret down

$184K - $287K *

Lead the charge in designing and deploying secure agentic AI systems, partnering with top-tier software companies to ensure robust solutions for enterprise demands in security, privacy, and performanc...

US-AnywhereRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$94K - $140K *

Champion security excellence by assessing risks, investigating incidents, and partnering with stakeholders to implement proactive cyber risk management strategies that safeguard clients from potential...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$106K - $148K *

Redefine security protocols and incident responses by leveraging expertise in network analysis, threat detection, and compliance frameworks to enhance organizational resilience and safeguard digital a...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$147K - $199K *

Contribute to dynamic frontend engineering, driving strategic direction and leading the development of user-centered web applications for government clients. Harmonize technical excellence with a stro...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Drive the strategic evolution of content authoring platforms, serve as a key technical liaison, and lead cross-functional discussions to ensure system interoperability while proactively managing proje...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$145K - $222K *

Optimize nuclear power plant systems design by leading modification projects, preparing technical documents, and collaborating with clients to ensure smooth operations and compliance with industry sta...

US-AnywhereRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$95K - $115K *

Shape the future by leading a dynamic support team. Oversee operations, mentor junior engineers, and enhance client relationships. Elevate technical projects while fostering a collaborative environmen...

US-AnywhereRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $195K *

Drive operational excellence by leading client success, operations, and implementation efforts. Cultivate teams, streamline processes, and ensure high-quality delivery for enterprise clients, all whil...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$113K - $170K *

Drive customer satisfaction by overseeing advanced troubleshooting, installations, and repairs of electronic equipment. Mentor junior engineers and manage escalations, ensuring compliance and effectiv...

US-AnywhereRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $132K *

Lead the charge in ensuring safety and health compliance for Antarctic operations, managing risk strategies and supporting diverse teams in extreme environments to enhance operational safety and stand...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$95K - $100K *

Lead the charge in advanced finance solutions, ensuring compliance and accuracy in government contracting. Collaborate with senior management to analyze performance risks and optimize financial strate...

US-AnywhereRemote

Yesterday

  •   Less than 5 years exp.  •   Aerospace & Defense

$112K - $150K *

Grow your career with a leadership position in software development, overseeing a dedicated team to deliver high-quality medical imaging solutions while ensuring compliance with healthcare regulations...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $166K *

Shape the future of renewable energy by leading SCADA designs for utility-scale projects, ensuring technical excellence and project success through collaboration and innovative solutions. Drive the qu...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $120K *

Collaborate with cross-functional teams to support the EPA's Next Generation Grant System, providing crucial Tier 1/2 Help Desk assistance while mastering user roles and ensuring efficient issue resol...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$81K - $115K *

Shape the future of user support by delivering exceptional Help Desk services, managing Tier 1/2 requests, and optimizing system functionalities within a collaborative team for essential government ap...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$86K - $138K *

Join a leading role as an Information Assurance and Security Engineer, delivering critical security expertise for a cloud-based system. Drive safe practices, ensure compliance, and enhance security po...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$120K - $165K *

Unlock the potential of cybersecurity by assessing and enhancing security controls, evaluating risks, and recommending corrective actions to ensure compliance with federal standards, driving effective...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$126K - $172K *

Empower your career by optimizing recruiting systems and enhancing the hiring experience. In this role, you'll manage ATS configurations, automate workflows, and support team operations to ensure effe...

US-AnywhereRemote

6 days ago

  •   5 - 7 years exp.  •   Staffing

$90K - $110K *

Join a team that's driving innovation in oncology by managing projects to advance approved imaging agents and late-stage products, enhancing lives through strategic planning, execution, and collaborat...

US-AnywhereRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$133K - $238K *

Empower the evolution of core technology platforms, uniting diverse teams to drive automation and robotics initiatives. Leverage your technical program management skills to deliver high-impact outcome...

US-AnywhereRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $160K *

Lead the charge in network engineering strategy and execution across the Americas. Drive modernization initiatives, manage multi-million dollar budgets, and enhance operational efficiency while foster...

US-AnywhereRemote

4 days ago

  •   11 - 15 years exp.  •   Telecommunications & Hardware

$125K - $150K *

Lead and innovate within identity governance services, overseeing a team to enhance security strategies and implementations for both human and non-human identities while collaborating cross-functional...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the commissioning strategy and execution for a large-scale data center project. Own the overall program, ensure multidisciplinary readiness, and manage vendor partners through various phases from...

US-AnywhereRemote

4 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$107K - $204K *

Accelerate your career by managing global trade compliance for F135 military programs. Collaborate cross-functionally to ensure adherence to U.S. regulations while supporting strategic objectives and...

US-AnywhereRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$220K - $292K *

Unlock potential by owning and enhancing a complex platform that powers model training and deployment. Collaborate closely with teams to architect reliable, cost-effective solutions that prioritize pe...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What does a Mission Systems Engineer do?question toggle

    A Mission Systems Engineer designs, maintains and enhances a variety of systems that are crucial for accomplishing a mission. This includes airborne systems, weapons systems, communication systems, and more.

  • How much can a Mission Systems Engineer earn?question toggle

    The salary for a Mission Systems Engineer can vary depending on experience and location, but jobs listed on Ladders pay $100,000 or more.

  • What types of companies hire Mission Systems Engineers?question toggle

    Industries such as Aerospace, Defense, IT, and Engineering Apps, among others, consistently need qualified Mission Systems Engineers.