Discover Microsoft Systems Engineer jobs with organizations seeking experienced professionals to design, implement, and support enterprise technology environments. These roles bring together expertise in Microsoft platforms, infrastructure, cloud services, security, and end-user computing. Ladders features vetted professional opportunities paying $100,000 or more, including positions for engineers who can keep complex systems reliable, secure, and ready to scale.
Microsoft Systems Engineers plan and maintain the systems that organizations rely on every day. Depending on the employer, responsibilities may include administering Windows Server environments, managing Microsoft 365 and Azure services, supporting identity and access management, automating deployments, and resolving infrastructure issues. Engineers may also contribute to architecture decisions, disaster recovery planning, endpoint management, and technical documentation.
Employers commonly look for hands-on experience with Microsoft technologies such as Windows Server, Active Directory or Microsoft Entra ID, Microsoft 365, Azure, and PowerShell. Knowledge of networking, virtualization, cloud operations, cybersecurity, and systems monitoring can strengthen an application. Clear communication and the ability to collaborate across IT, security, and business teams are also important, especially in senior and enterprise roles. Relevant Microsoft certifications may help demonstrate specialized expertise.
Microsoft Systems Engineers work across industries, including technology, finance, healthcare, manufacturing, and government. Career paths can lead to senior systems engineering, cloud engineering, infrastructure architecture, technical leadership, or IT management. The right opportunity depends on your platform expertise, preferred work environment, and whether you want to focus on cloud migration, enterprise operations, security, or automation.
Use Ladders to explore vetted Microsoft Systems Engineer opportunities paying $100,000 or more. Review job requirements, compare roles, and identify positions that align with your experience in Microsoft infrastructure and enterprise systems. New listings may be added regularly, so check back to find opportunities suited to your next career move.
Principal PATTS Consultant, State & Local Government
$140K - $210K *
Unlock the potential of Workday solutions by leading implementations, configuring systems, and ensuring client satisfaction. Collaborate with teams to document requirements, support data conversions...
1 week ago
$215K - $235K *
Advance drug substance development and drive clinical readiness projects by leading process chemistry initiatives, collaborating with cross-functional teams, and ensuring regulatory compliance for suc...
Reposted 2 weeks ago
$131K - $222K *
Shape the future of logistics by developing intelligent planning platforms that optimize freight movement. Collaborate with cross-functional teams to create scalable solutions that enhance supply chai...
1 week ago
Lead Mechanical Engineer 1 - Nuclear
$118K - $180K *
Join a team that's redefining nuclear power engineering by designing innovative systems and leading projects that enhance plant operations and safety. Collaborate with clients and drive impactful modi...
6 days ago
Lead Mechanical Engineer 1 - Nuclear
$118K - $180K *
Lead engineering projects in nuclear power systems design, focusing on modifications, analyses, and vendor evaluations. Collaborate with clients and teams to deliver innovative solutions that enhance...
6 days ago
$90K - $110K *
Champion growth by leveraging your engineering expertise to drive sales, build relationships, and expand market presence in a dynamic territory. Collaborate with teams to create impactful strategies a...
1 week ago
$143K - $208K *
Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...
Today
Director, 211 Manufacturing Quality and Regulatory Affairs
$190K - $228K *
Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...
Reposted 1 week ago
Senior Technical Product Manager
$153K - $213K *
Champion the development of a key platform, driving strategy, success metrics, and technical depth while collaborating across teams to deliver impactful solutions that meet customer needs and enhance...
2 weeks ago
Protection and Controls Engineer
$110K - $130K *
Innovate within a dynamic team to lead electrical engineering design for grid modernization projects. Drive client engagement and mentor junior engineers while ensuring high-quality deliverables in a...
5 days ago
Senior Engineering Manager (RD165)
$135K - $160K *
Empower a talented engineering team to develop innovative airgap-native software solutions. Drive product success in National Defense by ensuring seamless integration with UDS, fostering collaboration...
1 week ago
$137K - $231K *
Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...
1 week ago
$151K - $195K *
Join a team that's shaping the future of design engineering by developing innovative systems that enhance user experience across web and mobile platforms. Your expertise will drive quality and perform...
1 week ago
$125K - $150K *
Empower your career by leading and scaling a multidisciplinary engineering team in full-stack and data engineering. Drive impact through collaboration and technical excellence, ensuring quality and in...
Reposted 3 weeks ago
Lead Energetics Materials & Explosives Risk Management Engineer
$130K - $150K *
Pioneer safety solutions in explosives risk management. Leverage your extensive experience to lead high-stakes projects, mentor staff, and drive strategic improvements in risk mitigation across divers...
3 weeks ago
$100K - $120K *
Join a team that's driving successful IT solutions through strategic project management. Oversee complex projects from initiation to completion, ensuring alignment with client objectives while managin...
Today
Principal Technical Consultant - Forward Deployed Engineer, AI Security
$200K - $230K *
Lead a team that operationalizes advanced AI security solutions for enterprises, ensuring integration and compliance across environments. Collaborate with stakeholders to translate requirements into e...
4 weeks ago
$120K - $145K *
Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...
4 days ago
Teamcenter L2 Support Consultant
$84K - $131K *
Unlock your potential as a Lead Consultant, providing expert Level 2 support for Teamcenter PLM environments. Collaborate with cross-functional teams to resolve complex issues and ensure application s...
3 days ago
Power Plant Operations Support Manager
$170K - $195K *
Join a team that's dedicated to optimizing global power generation operations. You'll support fleet management, enhance O&M standards, and drive continuous improvement initiatives across a diverse por...
3 days ago
Clinical AI Technical Integration Specialist
$110K - $130K *
Unlock potential by driving technical integration and validation for Ambient AI Scribe initiatives. Collaborate with clinical teams to enhance workflows, troubleshoot issues, and ensure operational re...
1 week ago
Civil Project Engineer II/III - Renewable Energy Structural Design
$82K - $90K *
Engage in innovative structural design projects, focusing on renewable energy solutions. Collaborate with a dynamic team to develop project scopes, schedules, and budgets while enhancing your expertis...
6 days ago
Civil Project Engineer II/III - Renewable Energy Structural Design
$80K - $95K *
Join a team that's shaping the future of renewable energy through innovative civil engineering solutions. Contribute to the design of structures and bridges while managing projects and enhancing your...
3 weeks ago
Staff Software Engineer, Growth & Experimentation
$100K - $300K *
Lead the charge in optimizing the customer journey from landing page to long-term conversion. Drive growth through experimentation, retention strategies, and revenue expansion while collaborating with...
3 weeks ago
Project & Program Management III
$80K - $134K *
Lead the charge in managing large-scale Data Center projects, coordinating cross-functional teams to ensure timely delivery and adherence to budget. Drive innovative AI implementations while overseein...
5 days ago
What does a Microsoft Systems Engineer do?
A Microsoft Systems Engineer designs, operates, and improves technology environments built on Microsoft platforms. Common work includes managing Windows Server, Microsoft 365, Azure, identity services, security controls, automation, and infrastructure support.
What skills are needed for Microsoft Systems Engineer jobs?
Commonly requested skills include Windows Server administration, Microsoft 365, Azure, Active Directory or Microsoft Entra ID, PowerShell, networking, virtualization, troubleshooting, and security fundamentals. Requirements vary by role and employer.
Do Microsoft Systems Engineers need certifications?
Certifications are not required for every position, but relevant Microsoft credentials can help demonstrate platform knowledge. Employers may value certifications related to Azure, Microsoft 365, identity, security, or administration, alongside practical experience.
How much do Microsoft Systems Engineer jobs pay?
Compensation varies by experience, location, industry, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, where available salary information and requirements are listed with each opportunity.
Where can I find Microsoft Systems Engineer jobs paying $100,000 or more?
Explore Microsoft Systems Engineer listings on Ladders to find vetted professional opportunities with salaries of $100,000 or more. Compare job responsibilities and qualifications to identify roles that fit your background.