Microsoft Systems Engineer Jobs

Discover Microsoft Systems Engineer jobs with organizations seeking experienced professionals to design, implement, and support enterprise technology environments. These roles bring together expertise in Microsoft platforms, infrastructure, cloud services, security, and end-user computing. Ladders features vetted professional opportunities paying $100,000 or more, including positions for engineers who can keep complex systems reliable, secure, and ready to scale.

What Does a Microsoft Systems Engineer Do?

Microsoft Systems Engineers plan and maintain the systems that organizations rely on every day. Depending on the employer, responsibilities may include administering Windows Server environments, managing Microsoft 365 and Azure services, supporting identity and access management, automating deployments, and resolving infrastructure issues. Engineers may also contribute to architecture decisions, disaster recovery planning, endpoint management, and technical documentation.

Skills and Qualifications Employers Value

Employers commonly look for hands-on experience with Microsoft technologies such as Windows Server, Active Directory or Microsoft Entra ID, Microsoft 365, Azure, and PowerShell. Knowledge of networking, virtualization, cloud operations, cybersecurity, and systems monitoring can strengthen an application. Clear communication and the ability to collaborate across IT, security, and business teams are also important, especially in senior and enterprise roles. Relevant Microsoft certifications may help demonstrate specialized expertise.

Career Paths and Opportunities

Microsoft Systems Engineers work across industries, including technology, finance, healthcare, manufacturing, and government. Career paths can lead to senior systems engineering, cloud engineering, infrastructure architecture, technical leadership, or IT management. The right opportunity depends on your platform expertise, preferred work environment, and whether you want to focus on cloud migration, enterprise operations, security, or automation.

Find Microsoft Systems Engineer Jobs on Ladders

Use Ladders to explore vetted Microsoft Systems Engineer opportunities paying $100,000 or more. Review job requirements, compare roles, and identify positions that align with your experience in Microsoft infrastructure and enterprise systems. New listings may be added regularly, so check back to find opportunities suited to your next career move.

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$95K - $120K *

Lead the charge in administering and supporting Microsoft cloud and on-premises environments, ensuring seamless operations and project coordination for Microsoft 365 implementations while enhancing us...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Engage in diverse remediation projects, leading design and implementation efforts while ensuring project success through effective management and client engagement in a collaborative environment...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join a team that's dedicated to optimizing procurement processes and delivering effective SAP solutions. Collaborate with clients and cross-functional teams to enhance materials management and drive e...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$247K - $337K *

Lead CMC Pharmaceutical Development for small molecules, driving innovation and strategy from early development to commercialization while ensuring regulatory compliance and operational excellence...

New Jersey, USRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock your potential by leading technical execution of Electrification Solutions projects. Drive safety, quality, and customer satisfaction while managing resources and risks to ensure project succes...

Texas, USRemote

5 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Advance your career by joining a dynamic team focused on delivering innovative enterprise solutions. Engage with a variety of technologies while supporting mission-critical systems. Drive customer suc...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$190K - $200K *

Lead the charge in electrical engineering excellence across multiple campuses, ensuring robust design, validation, and energization of critical infrastructure while integrating onsite generation solut...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $210K *

Unlock the potential of Workday solutions by leading implementations, configuring systems, and ensuring client satisfaction. Collaborate with teams to document requirements, support data conversions...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$131K - $222K *

Shape the future of logistics by developing intelligent planning platforms that optimize freight movement. Collaborate with cross-functional teams to create scalable solutions that enhance supply chai...

Eden Prairie, MNRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$215K - $235K *

Advance drug substance development and drive clinical readiness projects by leading process chemistry initiatives, collaborating with cross-functional teams, and ensuring regulatory compliance for suc...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$118K - $180K *

Join a team that's redefining nuclear power engineering by designing innovative systems and leading projects that enhance plant operations and safety. Collaborate with clients and drive impactful modi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$118K - $180K *

Lead engineering projects in nuclear power systems design, focusing on modifications, analyses, and vendor evaluations. Collaborate with clients and teams to deliver innovative solutions that enhance...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Technical Services

$90K - $110K *

Champion growth by leveraging your engineering expertise to drive sales, build relationships, and expand market presence in a dynamic territory. Collaborate with teams to create impactful strategies a...

St. Paul, MNRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$143K - $208K *

Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$190K - $228K *

Drive enterprise Quality and Regulatory governance for U.S. operations, ensuring compliance with FDA regulations and overseeing manufacturing quality in the therapeutic radiopharmaceutical sector whil...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Empower a talented engineering team to develop innovative airgap-native software solutions. Drive product success in National Defense by ensuring seamless integration with UDS, fostering collaboration...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$137K - $231K *

Empower your career by shaping design systems that enhance user experience. Collaborate with teams to build high-quality, interactive UI across platforms, ensuring accessibility and performance while...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$151K - $195K *

Join a team that's shaping the future of design engineering by developing innovative systems that enhance user experience across web and mobile platforms. Your expertise will drive quality and perform...

CanadaRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$153K - $213K *

Champion the development of a key platform, driving strategy, success metrics, and technical depth while collaborating across teams to deliver impactful solutions that meet customer needs and enhance...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Innovate within a dynamic team to lead electrical engineering design for grid modernization projects. Drive client engagement and mentor junior engineers while ensuring high-quality deliverables in a...

Houston, TXRemote

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$125K - $150K *

Empower your career by leading and scaling a multidisciplinary engineering team in full-stack and data engineering. Drive impact through collaboration and technical excellence, ensuring quality and in...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $150K *

Pioneer safety solutions in explosives risk management. Leverage your extensive experience to lead high-stakes projects, mentor staff, and drive strategic improvements in risk mitigation across divers...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$200K - $230K *

Lead a team that operationalizes advanced AI security solutions for enterprises, ensuring integration and compliance across environments. Collaborate with stakeholders to translate requirements into e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $145K *

Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a team that's driving successful IT solutions through strategic project management. Oversee complex projects from initiation to completion, ensuring alignment with client objectives while managin...

Austin, TXRemote

Today

  •   Less than 5 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What does a Microsoft Systems Engineer do?question toggle

    A Microsoft Systems Engineer designs, operates, and improves technology environments built on Microsoft platforms. Common work includes managing Windows Server, Microsoft 365, Azure, identity services, security controls, automation, and infrastructure support.

  • What skills are needed for Microsoft Systems Engineer jobs?question toggle

    Commonly requested skills include Windows Server administration, Microsoft 365, Azure, Active Directory or Microsoft Entra ID, PowerShell, networking, virtualization, troubleshooting, and security fundamentals. Requirements vary by role and employer.

  • Do Microsoft Systems Engineers need certifications?question toggle

    Certifications are not required for every position, but relevant Microsoft credentials can help demonstrate platform knowledge. Employers may value certifications related to Azure, Microsoft 365, identity, security, or administration, alongside practical experience.

  • How much do Microsoft Systems Engineer jobs pay?question toggle

    Compensation varies by experience, location, industry, and role scope. Ladders focuses on vetted professional jobs paying $100,000 or more, where available salary information and requirements are listed with each opportunity.

  • Where can I find Microsoft Systems Engineer jobs paying $100,000 or more?question toggle

    Explore Microsoft Systems Engineer listings on Ladders to find vetted professional opportunities with salaries of $100,000 or more. Compare job responsibilities and qualifications to identify roles that fit your background.