Explore $100K+ Jobs in Oklahoma

Find professional opportunities across Oklahoma with salaries of $100,000 or more. Ladders features vetted jobs for experienced candidates seeking leadership, specialized, and other high-paying roles. Explore openings in Oklahoma City, Tulsa, and communities throughout the state, and discover opportunities that match your skills and career goals.

High-Paying Careers Across Oklahoma

Oklahoma’s economy includes established industries such as energy, aerospace, healthcare, manufacturing, finance, and technology. Employers may seek experienced professionals for roles in operations, engineering, corporate leadership, sales, information technology, and clinical or administrative management. Available positions and compensation vary by employer, location, experience, and specialization.

Find the Right Role for Your Experience

Use Ladders to explore vetted professional job listings and focus your search on roles with compensation of $100,000 or more. Review each posting for its responsibilities, qualifications, location, and compensation details. Set up a strong profile and tailor your resume to highlight measurable results, relevant expertise, and leadership experience.

Search Oklahoma Jobs on Ladders

Whether you’re considering a move to Oklahoma or looking to advance your career close to home, browse current high-paying opportunities and apply to positions that fit your background. New listings may appear as employers’ needs change, so check back regularly for the latest Oklahoma jobs.

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1,000+

Healthcare Jobs in Oklahoma

Average Salary in USD

Average Salary: $102,451

Sort By: Relevance

$80K - $95K *

Elevate your career by managing clinical sites and ensuring study quality, patient safety, and regulatory compliance. Collaborate with site teams to support enrollment and deliver impactful clinical r...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $130K *

Optimize multi-site outpatient clinical operations, ensuring safety, quality, and compliance while enhancing patient experience and employee engagement. Collaborate with leadership to implement strate...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$212K - $318K *

Shape the future of patient-centered outcomes in oncology by leading global strategies for clinical assessments and patient experience data, ensuring impactful evidence generation and regulatory succe...

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  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$121K - $182K *

Manage clinical monitoring activities for multiple trials, providing mentorship and oversight to CRAs. Collaborate with teams to ensure compliance and quality, while addressing site-level issues and e...

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  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$71K - $99K *

Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...

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  •   Less than 5 years exp.  •   Healthcare

$95K - $110K *

Transform patient care transitions by leveraging clinical expertise and consultative sales skills. Collaborate with healthcare teams to ensure safe, efficient home infusion therapy placements, enhanci...

Today

  •   Less than 5 years exp.  •   Healthcare

$108K - $147K *

Lead a dynamic team in enhancing member-centered care through effective utilization management. Drive quality improvement, ensure compliance, and foster strategic partnerships to optimize healthcare d...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$70K - $113K *

Lead the charge in advancing research strategy and operations at a premier lab. Collaborate with top scientists to enhance research initiatives, oversee operations, and foster a culture of excellence...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's dedicated to delivering exceptional emergency care, managing diverse patient needs with autonomy in a fast-paced environment. Collaborate with offsite physicians while practicing at...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$113K - $155K *

Champion quality excellence by executing business programs across manufacturing sites, collaborating with cross-functional teams to enhance product standards, manage consumer insights, and drive conti...

United StatesRemote

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  •   Less than 5 years exp.  •   Food & Beverages

$90K - $110K *

Lead the charge in optimizing clinic operations and patient care delivery. Oversee financial management, compliance, and strategic planning to enhance clinic performance and foster a positive work env...

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$145K - $218K *

Transform your career by driving clinical trial success through strategic site engagement and collaboration with key opinion leaders in Neuroscience and Oncology, enhancing patient enrollment and rete...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of healthcare by providing expert pharmacy consulting, enhancing patient safety, and delivering impactful clinical services while mentoring a skilled team in a dynamic environment...

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  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Elevate healthcare delivery by providing expert pharmacy consulting, medication education, and clinical services. Join a collaborative team committed to patient safety, mentorship, and continuous lear...

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$110K - $130K *

Reimagine patient care as a pharmacist, delivering expert consultations, ensuring medication safety, and mentoring a collaborative team while driving clinical healthcare innovation and personalized se...

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$67K - $111K *

Lead the charge in delivering compassionate, expert behavioral health care across diverse populations, ensuring continuity and support throughout each member's wellness journey while leveraging clinic...

United StatesRemote

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  •   5 - 7 years exp.  •   Healthcare

$77K - $202K *

Grow your career with us as you support healthcare payer platform modernization, analyze complex issues, and guide junior team members while enhancing client experiences and operational performance in...

Today

  •   Less than 5 years exp.  •   Legal & Accounting

$80K - $95K *

Lead the charge in managing site operations and vendor relations, ensuring compliance and efficiency in clinical research projects. Collaborate with teams to streamline processes and enhance training...

United StatesRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$67K - $110K *

Champion patient wellness by coordinating care, analyzing clinical data, and guiding chronic disease management. Collaborate with healthcare teams to enhance patient outcomes and ensure continuity of...

Today

  •   Less than 5 years exp.  •   Healthcare

$174K - $374K *

Inspire a culture of excellence as you lead a clinical team, ensuring top-tier patient care while mentoring providers. Balance clinical practice with strategic initiatives to enhance organizational gr...

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Develop high-quality, scientifically accurate content for medical affairs and promotional education. Collaborate with teams to ensure clarity and compliance while translating complex data into engagin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize customer adoption by leading product training and engagement, ensuring successful go-live and sustained usage. Act as a trusted radiology workflow consultant, driving deep product knowledge a...

United StatesRemote

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  •   Less than 5 years exp.  •   Healthcare

$72K - $97K *

Join a dynamic team to support global clinical study delivery, ensuring quality and compliance in clinical operations. Collaborate with cross-functional teams to manage study logistics, data tracking...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join our team to provide comprehensive medical care and treatments, ensuring ethical standards and patient management plans are upheld. Engage in community health initiatives while maintaining accurat...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Optimize clinical support for Heart Alert Service by reviewing ECG episodes, ensuring accurate documentation, and collaborating across functions to enhance patient care and workflow efficiency...

United StatesRemote

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  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs can I find in Oklahoma?question toggle

    Listings may include professional and leadership roles in areas such as energy, aerospace, healthcare, technology, manufacturing, finance, engineering, operations, and sales. Job availability and compensation vary.

  • Which Oklahoma cities have high-paying job opportunities?question toggle

    Opportunities may be available in Oklahoma City, Tulsa, and other communities across the state. Check each listing for its location and whether remote or hybrid work is offered.

  • Does Ladders list jobs that pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with compensation of $100,000 or more. Review individual postings for specific salary information and qualifications.

  • How can I find Oklahoma jobs that fit my experience?question toggle

    Search current listings and compare each role’s requirements, responsibilities, location, and compensation. Tailor your resume to emphasize relevant skills, accomplishments, and experience.