Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Average Salary: $106,679
Senior Medical Director - Oncology
$254K - $382K *
Transform clinical research by leading strategic medical initiatives, ensuring operational excellence, and fostering collaboration across teams. Drive innovation and mentor future leaders while delive...
2 days ago
Clinical Oversight Manager (COM) - USA
$110K - $130K *
Accelerate progress at the forefront of clinical research by ensuring effective oversight and management of clinical studies. Collaborate with teams to uphold quality standards and drive successful st...
2 days ago
Shreveport, LA based Clinical Specialist - Remote, USA
$100K - $140K *
Grow your career with a dynamic role in clinical support, training surgical teams, and ensuring optimal patient outcomes in complex procedures. Collaborate closely with medical professionals, manage i...
Reposted 2 days ago
Nurse Practitioner/Physician Assistant-HH Main Emergency Dept-FT-3rd Shift Weekends
$90K - $110K *
Contribute to comprehensive patient care by collaborating with physicians and a multidisciplinary team, performing diagnostics, and promoting health maintenance while engaging in ongoing professional...
2 days ago
Walker Baptist Medical Center - Full-Time CRNA
$190K - $250K *
Unlock potential by providing expert anesthesia care across diverse cases, ensuring patient safety and comfort. Collaborate with a dedicated team in a supportive environment, enjoying generous PTO and...
2 days ago
Crestwood Medical Center - Full-Time CRNA (10's)
$200K - $220K *
Transform the future of anesthesia care by joining a dedicated team providing comprehensive services in a supportive environment. Enjoy a balanced schedule with competitive compensation and generous b...
2 days ago
Crestwood Medical Center - Full-Time CRNA (8's)
$200K - $220K *
Join a team that's dedicated to providing exceptional anesthesia care. Enjoy a supportive environment where CRNAs can practice fully, with opportunities for growth and a competitive compensation packa...
2 days ago
$80K - $95K *
Empower healthcare solutions by supporting Epic application processes, enhancing operational efficiency, and ensuring system integrity through effective analysis, troubleshooting, and user collaborati...
Reposted 2 days ago
Nurse Practitioner - National After-Hours Team - Full Time - IA and MO Licensed
$95K - $115K *
Take ownership of after-hours telephonic care for aging residents, providing critical support and clinical direction across multiple states. Deliver high-quality, compassionate care while managing hig...
2 days ago
$75K - $90K *
Elevate patient care by preparing individuals for surgery through thorough assessments, education, and collaboration with surgical teams, ensuring a seamless and compassionate preoperative experience...
2 days ago
Program Manager, Medical Education
$120K *
Partner with us to enhance product knowledge through comprehensive training programs, ensuring effective customer support and the growth of clinical expertise in the field sales organization. Be a cli...
Reposted 2 days ago
Director, Field Medical Affairs, West Coast
$160K - $190K *
Champion a national team of Medical Science Liaisons focused on obesity, driving strategy and KOL engagement. Lead cross-functional collaboration and ensure compliance while developing high-performing...
Reposted 2 days ago
Director, Global Drug Safety & Pharmacovigilance Operations
$150K - $180K *
Advance global drug safety initiatives by leading pharmacovigilance activities, ensuring compliance with regulations, and collaborating with cross-functional teams to enhance product safety and operat...
2 days ago
Epic Systems Analyst - Ambulatory
$68K - $105K *
Transform your career by configuring and supporting Epic applications. Engage in systems analysis, design, and problem resolution while collaborating with end-users to enhance their experience and str...
2 days ago
$79K - $83K *
Transform student outcomes as a Speech Language Pathologist, evaluating and diagnosing communication disorders, developing tailored therapy plans, and collaborating with educators and families to enha...
2 days ago
Team Lead, Integrated Care Coordination - Waiver--Must live in Ohio
$72K - $115K *
Transform care coordination by leading a dedicated team, managing caseloads, and ensuring compliance with HCBS Waiver standards while enhancing member outcomes through effective oversight and support...
2 days ago
Clinical Documentation Integrity Supervisor
$110K - $159K *
Empower the Clinical Documentation Integrity team by ensuring staff competency through quality assurance, training, and performance management. Collaborate on action plans and foster associate develop...
2 days ago
ED, Advance Analytics and Precision Health
$225K - $418K *
Champion advanced analytics to enhance patient outcomes through data-driven insights. Lead a team in analyzing healthcare data, fostering strategic partnerships, and communicating complex findings to...
2 days ago
$80K - $95K *
Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...
2 days ago
Director, Patient Intelligence Strategy & Governance
$185K - $344K *
Advance enterprise patient intelligence by leading strategy, governance, and analytics. Collaborate across functions to enhance decision-making and drive insights that improve patient outcomes and bus...
2 days ago
Speech Language Pathologist - Maternity Leave Coverage
$83K - $87K *
Unlock potential by evaluating and diagnosing speech disorders, developing tailored therapy plans, and collaborating with educators and families to enhance student communication skills during maternit...
2 days ago
Senior Manager Medical Economics
$82K - $182K *
Analyze healthcare costs and quality outcomes to drive value-based care strategies, collaborating with clinical and financial teams. Lead data-driven insights and financial modeling to enhance operati...
Reposted 2 days ago
Biostatistical Programming Manager
$129K - $174K *
Lead a dynamic programming team to enhance data analysis strategies, ensuring high-quality biomedical data presentation while driving efficiency and innovation in a collaborative environment focused o...
2 days ago
$62K - $98K *
Elevate patient care as a vital member of the kidney care team, collaborating with healthcare professionals to develop personalized nutrition plans and improve health outcomes while enjoying professio...
2 days ago
Associate Director - Medical Science Liaison, Oncology (GI/Thoracic Focus) - Upper Midwest
$156K - $250K *
Lead the charge in scientific dialogue with key healthcare professionals, providing critical insights and support within your therapeutic area. Utilize your expertise to enhance patient outcomes and f...
Reposted 2 days ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.