Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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Healthcare Analyst Jobs in North Carolina

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$89K - $148K *

Unlock potential by ensuring data integrity and compliance across enterprise platforms. Collaborate with stakeholders to validate business processes, enhance data quality, and drive continuous improve...

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$81K - $95K *

Contribute to mission-critical operations by leveraging advanced data analysis and automation. Utilize your SQL expertise to transform complex datasets into actionable insights, supporting leadership...

5 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$165K - $195K *

Drive impactful healthcare commissioning projects by leading teams, managing client relationships, and ensuring compliance with industry standards. Collaborate across functions to enhance service deli...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $200K *

Unlock potential by defining and guiding enterprise architecture, integrating cloud, infrastructure, and security to support business priorities. Lead modernization efforts and influence cross-functio...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Healthcare

$113K - $188K *

Shape the future of healthcare reimbursement by developing and implementing payment policies that enhance accuracy, compliance, and provider experience in a dynamic payer environment. Collaborate with...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$81K - $108K *

Unlock potential by enhancing data quality and governance, ensuring effective modeling and standards. Collaborate with teams to drive process improvements and support data-driven decision-making acros...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Analyze financial performance and operational metrics to support strategic growth initiatives. Collaborate with cross-functional teams to enhance reporting accuracy and drive insights for decision-mak...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$119K - $179K *

Lead the charge in architecting FHIR-compliant data models to enhance clinical data integration and usability, supporting patient care and research initiatives across the organization...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential by driving business application solutions and leading requirements elicitation. Collaborate across teams to enhance processes and systems, ensuring alignment with business object...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Lead the charge in driving business application solutions through process design and analysis. Collaborate across teams to gather requirements, manage projects, and enhance business operations while i...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Partner with us to enhance clinical IT solutions as an Epic Analyst II, providing critical support, training, and implementation for Epic EHR systems. Collaborate with teams to optimize workflows and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $142K *

Unlock potential by leading innovative provider reimbursement initiatives, managing complex contracts, and collaborating with stakeholders to enhance healthcare delivery and network capabilities...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$73K - $110K *

Transform data into insights by joining a dynamic team focused on bioinformatics. Collaborate with researchers to develop innovative tools and analyses that advance cancer research through cutting-edg...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $110K *

Join a team that's dedicated to advancing cancer research through bioinformatics. Collaborate with researchers to develop innovative data analysis tools and support high-throughput studies, enhancing...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$131K - $303K *

Join a team that's at the forefront of healthcare analytics, driving innovation and strategy. You will support financial stewardship, operational excellence, and executive communications in a high-vis...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the cybersecurity validation and risk management processes to ensure IT systems comply with requirements, fostering a secure environment while guiding junior team members in their operational tas...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Join a dynamic nursing team in a fast-paced observation unit, providing compassionate care to acute patients. Utilize your skills in a supportive environment focused on patient safety and experience...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $90K *

Engage in data analysis and communications to support strategic planning and policy review for federal programs. Collaborate with stakeholders to ensure timely responses and effective execution of hig...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$175K - $210K *

Lead the charge in driving enterprise growth within healthcare by building relationships with national and regional health plans. Own new logo acquisition and expansion, leveraging a robust support sy...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $150K *

Drive healthcare transformation by leading strategic initiatives in oncology navigation. Leverage your expertise to enhance patient access to cancer care, shape effective programs, and foster partners...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $127K *

Drive your career forward by overseeing tax compliance and accounting functions. You'll conduct research, manage filings, and identify opportunities while ensuring adherence to evolving tax laws. Join...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$66K - $106K *

Join a team that's dedicated to analyzing Medicaid policies across the northeastern states. As a subject matter expert, you'll research regulations, educate teams, and contribute to project developmen...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$110K - $225K *

Lead the charge in advancing healthcare insights through strategic research and analytics. Collaborate with teams to drive growth, enhance client relationships, and deliver impactful solutions that al...

Reposted 2 days ago

  •   11 - 15 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.