Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$70K - $100K *
Join a team that's committed to financial excellence, ensuring accuracy and compliance in accounting operations. Lead month-end closes, enhance reporting, and drive process improvements while mentorin...
Today
Supervisor Cardiac Cath Lab - CMC Main Sanger Heart & Vascular
$99K - $148K *
Champion patient care by leading a dynamic team in a fast-paced Cardiac Cath Lab. Oversee operations, ensure compliance, and drive staff development while enhancing patient outcomes and safety in a co...
4 days ago
$227K - $341K *
Lead the strategic development and continuous improvement of clinical programs, focusing on optimizing patient care across the continuum. Oversee a multidisciplinary team to enhance outcomes, reduce h...
3 days ago
$145K - $155K *
Accelerate the evolution of data analytics by leading modernization efforts, optimizing reporting capabilities, and fostering strategic partnerships across functions to drive data-driven decision-maki...
2 days ago
Senior Program Control Manager / Budget Analyst
$100K - $120K *
Transform budget planning and execution within clinical informatics, leveraging expertise in PPBE and MFR practices. Collaborate with leadership to ensure financial strategies align with healthcare in...
4 weeks ago
Strategic Client Consultant I - National Accounts
$80K - $95K *
Transform client relationships by driving retention and growth through strategic insights and data analysis. Lead negotiations with complex clients, ensuring profitable partnerships while collaboratin...
2 days ago
$104K - $143K *
Shape the future of pharmacy software by leading product strategy, managing cross-functional teams, and driving improvements in patient outcomes and business results through innovative product managem...
Today
GCG Operating Office - Analyst
$80K - $95K *
Champion operational excellence by driving financial analysis and strategic planning. Collaborate with senior leaders to enhance sales management and optimize performance across the Global Client Grou...
3 weeks ago
$180K - $220K *
Join our team to provide comprehensive dermatological care, collaborating with medical staff to enhance patient outcomes. You'll manage both inpatient and outpatient cases, ensuring effective communic...
3 weeks ago
$74K - $87K *
Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...
3 weeks ago
System Vice President State Government Affairs
$160K - $200K *
Lead strategic state government affairs initiatives, shaping policy and advocacy efforts. Collaborate with diverse stakeholders to align organizational priorities with legislative agendas, ensuring im...
1 week ago
Associate Medical Director, Clinical Research
$225K - $281K *
Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...
3 weeks ago
Associate Medical Director, Clinical Research
$225K - $281K *
Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...
3 weeks ago
Program Manager, Client Services, Clinical Trial Support
$88K - $105K *
Lead the charge in managing client relationships and program performance, ensuring timely delivery of medications. Oversee budgets, facilitate communication between stakeholders, and drive successful...
5 days ago
Lead Engineer Stability Analysis-2
$85K - $164K *
Join a team that's dedicated to enhancing reactor safety through advanced thermal-hydraulic stability analyses. Collaborate across disciplines to support operational needs and fuel-related projects fo...
5 days ago
$147K - $217K *
Join a team that's redefining analytics in life sciences. Lead innovative measurement strategies, mentor talent, and drive impactful client solutions while navigating complex data ecosystems and foste...
2 weeks ago
$147K - $217K *
Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...
2 weeks ago
$95K - $115K *
Drive patient care excellence as a Physician Assistant or Nurse Practitioner, collaborating with a multidisciplinary team to provide comprehensive medical services in both inpatient and outpatient set...
2 weeks ago
Director of Business Development
$110K - $130K *
Unlock potential by driving strategic partnerships and expanding client relationships. Lead business growth initiatives while effectively managing complex accounts in the clinical research sector. Col...
3 weeks ago
Director of Business Development
$110K - $130K *
Lead the charge in expanding strategic partnerships and driving growth initiatives with autonomy. Collaborate with leadership to assess market trends, enhance client relationships, and achieve sales t...
3 weeks ago
$90K - $110K *
Advance your career by providing comprehensive care in a respected family practice. Collaborate with specialists and engage with the community while managing acute and chronic health issues in a suppo...
2 weeks ago
$70K - $110K *
Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...
3 days ago
Nurse Practitioner or Physician Assistant
$90K - $110K *
Optimize patient care as a Nursing Practitioner or Physician Assistant, overseeing clinical operations while enhancing patient experiences. Collaborate with healthcare teams and participate in ongoing...
Reposted 3 weeks ago
Manager, Health Informatics (Pacific Southwest)
$152K - $253K *
Elevate healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align technolo...
Today
Senior Software Engineer (New Health Care Company)
$106K - $145K *
Join us to lead the development of innovative software solutions for the healthcare industry, ensuring high-quality standards and security practices while collaborating with global teams to solve comp...
2 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.