Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Project Manager - CNS (North America)
$128K - $254K *
Drive the successful delivery of Phase I-IV clinical trials by leading cross-functional teams, managing project timelines, budgets, and quality standards while fostering strong client relationships an...
Reposted 4 days ago
$100K - $120K *
Drive strategic oversight of enterprise-wide RAC audit activities, ensuring compliance and operational excellence. Collaborate with leadership to enhance audit processes, minimize financial risk, and...
6 days ago
Nurse Manager - Oncology Infusion Cary, NC
$85K - $100K *
Drive clinical excellence and operational leadership in ambulatory clinics, ensuring high standards of patient care, regulatory compliance, and effective resource management while fostering quality im...
1 week ago
Enterprise Service and Configuration Management Analyst
$66K - $106K *
Optimize IT service delivery by managing configuration items, analyzing operational data, and ensuring effective incident resolution. Collaborate with cross-functional teams to enhance service perform...
2 weeks ago
Associate - Financial Planning & Analysis (FP&A)
$80K - $95K *
Empower your career by driving financial insights and analytics. Collaborate across teams to transform data into strategic decisions, enhancing growth and efficiency in a dynamic environment. Join us...
Today
$129K - $177K *
Shape the future of developer tooling by leading strategy and governance for an enterprise ecosystem. Collaborate with cross-functional teams to enhance developer experience, drive automation, and ens...
3 days ago
$210K - $225K *
Pioneer innovative research strategies to enhance clinical outcomes and drive impactful insights through collaboration across teams, while establishing a robust research infrastructure and publication...
3 weeks ago
$103K - $128K *
Shape the future of healthcare by driving risk adjustment solutions that enhance interoperability, improve documentation accuracy, and ensure compliance across Medicare, Medicaid, and ACA programs thr...
Reposted 1 week ago
$103K - $128K *
Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...
3 weeks ago
$100K - $120K *
Join a team that's enhancing employee engagement and compliance through effective HR leadership. Oversee recruitment, onboarding, and support leadership in fostering a positive workplace culture acros...
3 weeks ago
Project Manager, FEHRM Healthcare Technology Management - Deployment
$95K - $125K *
Drive the deployment of healthcare technology across multiple VA facilities, coordinating projects and ensuring readiness. Collaborate with diverse teams to manage timelines, resolve issues, and deliv...
2 weeks ago
Sr. Manager, AI Performance & Operations
$110K - $173K *
Join a team that's redefining AI-driven quality and performance operations. You'll build systems that enhance frontline team effectiveness and AI agent performance, ensuring impactful coaching and fee...
3 weeks ago
Senior Epidemiological Programmer, Real World Evidence - FSP
$88K - $220K *
Lead the development of analytic datasets and conduct longitudinal analyses for observational studies in virology. Collaborate with epidemiologists and manage complex analyses while ensuring adherence...
1 week ago
Sr Analyst - Red Team Operator
$110K - $130K *
Lead and execute advanced red team operations, emulating real-world threats across diverse technology environments. Collaborate with security teams to enhance detection, response, and operational secu...
1 week ago
$105K - $129K *
Lead the charge in providing comprehensive care across independent, assisted, and skilled living environments. Manage outpatient practices, oversee clinical operations, and enhance resident well-being...
5 days ago
$89K - $113K *
Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...
Yesterday
$140K - $170K *
Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...
2 weeks ago
Network Development Specialist
$86K - $124K *
Unlock opportunities in healthcare by managing relationships with providers and partners. Drive value-based care initiatives, enhance clinical integration, and support network growth through strategic...
Today
$110K - $130K *
Transform early phase clinical trials by leading design, execution, and oversight. Collaborate with cross-functional teams to ensure compliance and data integrity while managing project performance an...
3 weeks ago
EDI Analyst/Transaction Specialist
$85K - $116K *
Shape the future of EDI transactions by ensuring accurate processing, compliance, and data validation. Collaborate with stakeholders to troubleshoot issues and enhance operational efficiency in a dyna...
2 days ago
$68K - $143K *
Unlock innovative financial processes by driving transformation in logistics integration and optimizing resource allocation. Collaborate with diverse teams to enhance financial operations within the D...
Reposted 4 days ago
Strategic Account Manager, Rare Disease, Raleigh, NC
$146K - $211K *
Unlock your potential as a key player in driving sales and optimizing care pathways for rare disease patients. Collaborate with stakeholders to enhance patient outcomes and achieve strategic goals acr...
Reposted 2 weeks ago
$113K - $188K *
Join a dynamic team to design and develop high-performance ETL solutions, integrating data from diverse sources. Collaborate with cross-functional teams to optimize data workflows and ensure complianc...
2 weeks ago
Mobile Director of Nursing (DON)
$90K - $110K *
Transform nursing excellence by leading and managing nursing departments across facilities. Utilize your expertise to ensure compliance, enhance quality outcomes, and drive operational success in a dy...
2 weeks ago
Mobile Director of Nursing (DON)
$90K - $110K *
Elevate nursing standards by leading and managing nursing departments across multiple facilities. Utilize your expertise to ensure compliance with regulations, enhance quality outcomes, and foster a c...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.