Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Wealth Institutional Administration and Operations Senior Analyst
$80K - $95K *
Transform client experiences by managing complex accounts, ensuring efficient operations, and enhancing service delivery. Collaborate with teams to streamline processes and maintain high standards of...
5 days ago
Nurse Practitioner OR Physician Assistant
$90K - $110K *
Manage primary medical care within an occupational health program, ensuring quality patient management, diagnostic testing, and therapeutic procedures while collaborating with healthcare professionals...
3 weeks ago
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Shape innovative data management solutions for Life Sciences, focusing on Customer MDM and data governance. Lead client engagements, drive commercial transformation, and foster high-performing teams t...
3 days ago
$168K - $231K *
Join a dynamic team to lead Nurse Case Managers, enhancing patient support and education throughout treatment journeys while ensuring compliance and quality in case management processes...
3 days ago
Hospice & Palliative - NP - Full-Time
$99K - $148K *
Help us deliver quality palliative care through comprehensive patient assessments, treatment planning, and collaborative support. Engage with patients and teams to ensure excellent health outcomes and...
Reposted 3 weeks ago
Project Manager, FEHRM Healthcare Technology Management - Interoperability
$95K - $125K *
Advance your career by coordinating healthcare technology integration across multiple VA sites. Leverage your project management skills to support the Federal Electronic Health Record Modernization pr...
3 weeks ago
Senior Information Governance Advisor
$114K - $218K *
Lead the charge in establishing and enforcing data governance policies, ensuring data quality and compliance. Collaborate across teams to drive initiatives that enhance operational data integrity and...
1 week ago
Registered Nurse (RN) - Providence Emergency Department
$79K - $118K *
Drive excellence in patient care by utilizing your RN expertise in a dynamic emergency department. Collaborate with a dedicated team to enhance patient outcomes and uphold safety standards while manag...
3 days ago
Analyst, Specialty Underwriter and Portfolio Manager - CRE
$119K - $136K *
Lead the charge in underwriting and managing commercial real estate portfolios, ensuring risk mitigation and compliance while collaborating with internal teams to support business growth and operation...
Today
Registered Nurse (RN) - Float Pool
$79K - $118K *
Contribute to exceptional patient care by providing skilled nursing across multiple units, adapting to diverse clinical environments while ensuring safety and quality standards are met. Collaborate wi...
5 days ago
Healthcare Payments Sales Consultant
$157K - $192K *
Drive strategic payment solutions by connecting client needs with integrated services. Elevate account growth through proactive engagement while simplifying the sales process for institutional clients...
Reposted 4 days ago
Vice President, Medicare Partnerships
$150K *
Lead the charge in driving Medicare partnerships, enhancing contract value, and achieving growth targets through strategic sales initiatives and relationship management with health plans...
2 weeks ago
IT Auditor Sr - Audit Services
$80K - $115K *
Join a team that's dedicated to enhancing IT governance and security. Lead audits and advisory engagements to identify risks, assess controls, and provide actionable recommendations, ensuring complian...
1 week ago
AI & GenAI Data Scientist-Director
$155K - $410K *
Empower growth through innovative AI solutions! As a leader in data science, design transformative systems, inspire teams, and engage with clients to convert insights into impactful strategies using c...
Reposted 2 weeks ago
AI & GenAI Data Scientist-Director
$155K - $410K *
Join a team that's leveraging AI and Machine Learning to transform data into strategic insights, overseeing multiple projects while mentoring future leaders and ensuring client satisfaction in a dynam...
Reposted 2 weeks ago
$172K - $236K *
Elevate health solutions by bridging product strategy and architecture across diverse segments, ensuring integrated delivery. Guide cross-functional teams in defining roadmaps and architectural standa...
Reposted today
Registered Nurse (RN) - Atrium Health Bariatric Outpatient Pineville FT Days
$73K - $110K *
Join a team that's dedicated to delivering exceptional patient care in a multidisciplinary outpatient setting, focusing on obesity medicine and weight management. Collaborate with healthcare professio...
Today
Senior Case Manager RN - Oncology (Remote)
$79K - $127K *
Partner with us to deliver comprehensive case management services, ensuring quality care and optimal health outcomes for members with complex needs. Collaborate with healthcare teams to develop and im...
2 weeks ago
Senior Manager, Business Controls and Governance
$67K - $199K *
Elevate the governance and control environment by partnering with operational teams to manage risk, ensuring compliance with SOX and SOC 1 standards while driving sustainable solutions across Service...
Reposted 2 days ago
Environmental Policy & Compliance Analyst
$100K - $150K *
Lead the charge in environmental policy analysis and compliance, ensuring adherence to NEPA and other regulations. Collaborate with agencies, conduct research, and draft reports to support sustainable...
4 days ago
Technical Client Success Specialist
$70K - $110K *
Lead the charge in ensuring an exceptional client experience by bridging communication between internal teams and clients, fostering strong relationships, and proactively addressing client needs while...
3 weeks ago
$120K - $150K *
Champion social strategy and community engagement, driving impactful growth across multiple channels. Lead a dynamic team to create culturally relevant content, leveraging AI for efficiency and innova...
2 weeks ago
Manager, Data Analytics- Industrial
$100K - $150K *
Take ownership of robust data infrastructure and analytics for the National Industrial platform. Collaborate cross-functionally to enhance decision-making and streamline processes through advanced dat...
Reposted 6 days ago
Organizational Development Analyst
$72K - $135K *
Champion the design and delivery of impactful learning initiatives, ensuring alignment with business needs while enhancing the learner experience across a global Operations organization...
4 days ago
$95K - $115K *
Unlock the potential of HR technology by designing and implementing advanced Workday solutions. Collaborate with cross-functional teams to enhance integrations, reporting, and automation, driving oper...
Today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.