Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Data Scientist, Project Success and Innovation
$114K - $140K *
Pioneer innovative solutions as a Data Scientist, driving advanced analytics and machine learning applications to enhance project success and economic opportunities across diverse teams and workflows...
1 week ago
LTSS & Dual Eligible Program Report Developer IV
$94K - $164K *
Empower healthcare outcomes by engaging in data analytics and reporting. This senior role manages complex datasets, collaborates with cross-functional teams, and creates dashboards to enhance operatio...
4 weeks ago
Clinical Project Research Manager - EDS/RWE/NIS
$110K - $130K *
Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...
4 days ago
Clinical Genomics Advanced Practice Provider
$110K - $130K *
Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...
3 days ago
System Implementation Specialist
$75K - $120K *
Advance your career by implementing innovative SaaS solutions, configuring custom workflows, and driving system integration projects. Collaborate with a dynamic team to tackle complex challenges and d...
3 weeks ago
$83K - $105K *
Lead the charge in safeguarding sensitive data by managing DLP operations, investigating incidents, and collaborating with cross-functional teams to enhance data protection strategies across various e...
1 week ago
Manager, Allied Health Services
$96K - $141K *
Lead the charge in enhancing pediatric care by managing allied health services, ensuring evidence-based practices, and fostering clinical excellence for optimal patient outcomes and family engagement...
1 week ago
$95K - $115K *
Unlock potential by shaping innovative solutions for Opioid Treatment Programs and Medication Assisted Treatment. Collaborate with clients and teams to translate complex needs into actionable product...
3 weeks ago
$110K - $130K *
Transform data into actionable insights by building robust data pipelines, dashboards, and monitoring frameworks. Leverage expertise in Skyline DataMiner to enhance network performance analytics and e...
3 weeks ago
Medical Director, Post-Service Review & Medical Claims Review (MCR)
$195K - $341K *
Engage in clinical oversight and support staff training while ensuring adherence to quality standards and regulatory compliance in a collaborative healthcare environment focused on member care and ope...
4 weeks ago
Registered Nurse (RN) - Atrium Health Biddle Point Family Medicine FT
$73K - $110K *
Join a team that's dedicated to delivering exceptional patient care while overseeing clinical staff in a dynamic family medicine setting. Collaborate with a diverse group of healthcare professionals t...
Reposted 2 weeks ago
Registered Nurse I Ambulatory & Outpatient - Sanger Heart & Vascular
$73K - $110K *
Join a team that's dedicated to delivering exceptional patient care through evidence-based practices, collaboration, and continuous improvement. This role involves assessing, planning, and implementin...
1 week ago
$80K - $128K *
Elevate cybersecurity operations by monitoring threats, analyzing network traffic, and coordinating incident responses. Collaborate with teams to enhance security measures and mentor junior analysts w...
Today
Senior Manager, Payer Negotiation Strategy and Market Intelligence
$82K - $182K *
Take ownership of payer negotiation strategies and tools to enhance negotiation effectiveness. Translate market insights into actionable playbooks and frameworks that drive consistency, confidence, an...
Reposted 2 weeks ago
Senior Network Medical Director, West Region
$184K - $396K *
Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...
Reposted 1 week ago
Financial Analyst Lead - AI Technology
$127K - $243K *
Shape financial strategies by leading a team to deliver advanced analytics and insights. Drive complex problem-solving and mentor others while ensuring compliance and effective workflow management in...
1 week ago
SAP Data Workstream Lead EDW/Snowflake
$110K - $130K *
Empower your career by leading complex SAP data integration and migration workstreams. Drive project delivery, manage teams, and ensure data accuracy from requirements to production in a dynamic envir...
1 week ago
Senior Human Resources Business Partner
$88K - $105K *
Champion a dynamic atmosphere as you drive HR strategies, enhance employee engagement, and foster a thriving workplace culture. Collaborate with leadership to implement initiatives that strengthen org...
Reposted 2 days ago
Cyber Security Specialist Lead
$96K - $133K *
Support our cyber defense initiatives by leading incident response efforts, analyzing security events, and optimizing detection capabilities to enhance network security and protect sensitive data...
3 weeks ago
Experienced Clinical Research Associate | Regionally Aligned Across US
$80K - $95K *
Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...
6 days ago
$90K - $110K *
Elevate your career by providing quality healthcare in a correctional setting. Collaborate with a dedicated team to deliver essential medical services, manage chronic conditions, and respond to emerge...
3 weeks ago
$120K - $160K *
Transform data into actionable insights by owning the analytics pipeline from ingestion to visualization. Collaborate with cross-functional teams to create trusted models and metrics that empower deci...
3 days ago
$90K - $144K *
Elevate our IT team by leading the development of Robotic Process Automation solutions. Collaborate with peers to drive automation and AI initiatives, ensuring successful implementation and optimizati...
2 weeks ago
$90K - $110K *
Unlock your potential by building modern analytics solutions with Microsoft Fabric, Power BI, and SQL. Collaborate across teams to deliver data-driven insights and support decision-making through effe...
4 days ago
$150K - $195K *
Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...
2 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.