Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$133K - $173K *
Architect product strategies and roadmaps for complex solutions, driving innovation and collaboration across teams to enhance user experiences and operational effectiveness while ensuring alignment wi...
5 days ago
Healthcare Regulatory Assurance Lead
$119K - $175K *
Optimize healthcare compliance by leading regulatory assurance efforts, ensuring adherence to HIPAA, HITECH, and HITRUST standards while collaborating with clinical leadership to maintain a defensible...
6 days ago
$110K - $130K *
Transform business strategies into actionable insights by leading analytics projects, engaging stakeholders, and designing key performance metrics that drive strategic decision-making and enhance data...
2 weeks ago
$80K - $100K *
Drive innovative palliative care solutions for members with complex needs, providing compassionate, evidence-based support through telehealth. Collaborate with interdisciplinary teams to enhance patie...
3 weeks ago
Senior Quality Operations Specialist, Audit
$74K - $98K *
Champion regulatory audit excellence by leading PACE audits, ensuring compliance, and driving cross-functional collaboration to enhance operational readiness and continuous improvement across the orga...
2 weeks ago
Physical Therapist - Outpatient In Home Therapy
$73K - $110K *
Transform your career by delivering personalized outpatient physical therapy in patients' homes. Collaborate with a dedicated team to enhance mobility and independence while utilizing innovative care...
1 week ago
Director, Health Plans (Account Executive)
$120K - $135K *
Support the growth of health plan accounts by fostering client relationships, analyzing data, and driving retention in a fast-paced, independent role. Leverage strong communication and analytical skil...
3 weeks ago
$112K - $131K *
Elevate your career by leading complex financial analyses and strategic initiatives. As a senior contributor, you'll drive enhancements in reporting, support business decisions, and mentor team member...
2 weeks ago
Senior Product Analytics Engineer
$142K - $186K *
Pioneer a data-driven culture by designing scalable ELT pipelines and analytics models. Collaborate across teams to ensure product data integrity and empower stakeholders with self-service insights, d...
2 weeks ago
Registered Nurse (RN) Atrium Health One Health Family Medicine and Urgent Care
$79K - $118K *
Empower patient care by joining a dynamic team as a Registered Nurse, providing essential support in a fast-paced ambulatory environment, ensuring high-quality, patient-centered care for diverse popul...
2 weeks ago
Business Analyst (ITSM Platform Requirements)
$72K - $111K *
Drive impact by analyzing ITSM platform requirements, collaborating with stakeholders to develop solutions, and supporting the ITCR process, ensuring efficient delivery of enterprise IT customer suppo...
3 weeks ago
Lead Solutions Engineer, Strategic
$140K - $170K *
Shape the future of healthcare technology by leveraging your expertise to drive sales success. Collaborate with cross-functional teams to deliver tailored solutions, engage customers, and enhance prod...
1 week ago
Home Health Registered Nurse Case Manager
$77K - $106K *
Deliver exceptional home health nursing care, collaborating with healthcare teams to develop personalized care plans, monitor patient progress, and educate families, ensuring quality support in patien...
1 week ago
Home Health Registered Nurse Case Manager
$77K - $106K *
Join a team that delivers personalized home health care, empowering patients to regain independence. Collaborate with healthcare professionals to manage care plans, monitor progress, and educate famil...
1 week ago
Director, Enterprise Portfolio Management
$150K - $195K *
Drive change management initiatives that enhance employee engagement and operational efficiency. Collaborate across teams to ensure successful adoption of technology and policy changes, while providin...
2 weeks ago
AI Forward Deployed Engineer - Finance-focused (US)
$121K - $240K *
Engage finance teams by developing AI-driven tools that enhance analysis, streamline close activities, and improve data accessibility. Collaborate with stakeholders to create impactful solutions that...
Reposted 4 days ago
AI Forward Deployed Engineer - Finance-focused (US)
$121K - $240K *
Innovate finance operations by developing AI-driven tools that enhance analysis and streamline processes. Collaborate with finance teams to create impactful solutions that improve decision-making and...
3 weeks ago
Auditor Clinical Validation Outpatient Specialty Clinical
$95K *
Advance your career by auditing outpatient and specialty claims, ensuring coding accuracy and compliance. Leverage your clinical and coding expertise to enhance audit processes and contribute to quali...
3 weeks ago
Sr. Strategic Account Executive, MarketScan
$239K - $358K *
Join a team that's committed to maximizing growth in pharmaceutical accounts through strategic planning and relationship building, focusing on data-driven solutions and real-world evidence to foster l...
Reposted 2 weeks ago
Associate Director, Analytics and Data Products
$125K - $145K *
Lead the charge in building and delivering data products that empower leadership and client engagements. This hands-on role requires strategic oversight and collaboration to ensure high-quality analyt...
3 days ago
Investment Banking Analyst, Class of 2027
$110K *
Launch your career by supporting M&A transactions in healthcare. Collaborate with senior bankers, engage with clients, and develop financial models while gaining invaluable experience in a dynamic inv...
1 week ago
Registered Nurse (RN)- Medical Oncology ICU
$79K - $118K *
Join a dedicated team in our unique Medical Oncology ICU, delivering expert care and support to complex cancer patients. Collaborate with specialists in a high-acuity environment devoted to healing an...
1 month ago
Registered Nurse - Levine Cancer Oncology Infusion
$73K - $110K *
Empower patient care by utilizing your nursing expertise to assess, plan, and implement effective treatment strategies. Collaborate with a dedicated team to enhance outcomes and engage patients throug...
2 weeks ago
Certified Registered Nurse Anesthetist - CRNA
$160K - $200K *
Join our team to deliver high-quality anesthesia care across diverse settings. Collaborate with healthcare professionals, manage patient safety, and implement advanced pain management techniques while...
3 weeks ago
$130K - $150K *
Lead the charge in integrating complex hospital data systems into Astra OS. Own end-to-end data pipelines, collaborate with customers, and design scalable solutions that enhance healthcare operations...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.