Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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Healthcare Analyst Jobs in North Carolina

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$79K - $118K *

Join a dynamic team providing evidence-based physical therapy in a fast-paced inpatient rehabilitation setting. Collaborate with multidisciplinary professionals to deliver patient-centered care for di...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $132K *

Drive IT and Data risk management initiatives by leading assessments, monitoring compliance, and collaborating with stakeholders to enhance risk mitigation strategies across the organization, ensuring...

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$155K - $259K *

Transform healthcare performance by leading integrated optimization programs that enhance clinical, operational, and financial outcomes for hospitals and health systems. Drive measurable results throu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$82K - $172K *

Transform data strategies by leading the development of scalable analytics processes and tools. Collaborate with teams to enhance decision-making through advanced modeling and automation, ensuring rel...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Advance clinical trial success by managing operations, timelines, and quality. Collaborate with teams to ensure compliance and foster stakeholder relationships while driving strategic decisions for im...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $235K *

Drive growth by leveraging your consultative sales expertise to engage higher education leaders, aligning their needs with innovative research solutions while managing client relationships and achievi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $110K *

Join a dynamic team as a Physician Assistant, delivering quality care in an autonomous setting while collaborating with experienced clinical teams. Enjoy a predictable schedule and a supportive enviro...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive high-impact BI solutions by shaping organizational data strategy, overseeing compliance, and ensuring innovation within the Patient Revenue Management Organization. Collaborate with leadership t...

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$107K - $147K *

Unlock potential by ensuring accurate and timely external financial reporting. Collaborate with cross-functional teams to enhance compliance and operational efficiency while driving continuous improve...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$118K - $189K *

Transform data into actionable insights by leading innovative actuarial solutions. Drive the development of complex data systems, ensuring accuracy and quality for financial reporting while collaborat...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$70K - $95K *

Analyze complex datasets and drive strategic insights as an embedded analytical partner. Collaborate with cross-functional teams to design, build, and execute data-driven solutions that enhance busine...

Today

  •   Less than 5 years exp.  •   Healthcare

$145K - $191K *

Lead the charge in designing scalable cloud solutions that meet diverse healthcare needs, ensuring alignment with enterprise architecture and driving technology initiatives across multiple platforms t...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K *

Champion quality assurance by developing and executing test strategies to ensure technology solutions meet business and user requirements. Collaborate with cross-functional teams to enhance applicatio...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Drive regulatory strategy across major programs, leading high-impact submissions and authority engagement. Collaborate with cross-functional teams to optimize clinical development and ensure complianc...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to transforming complex business needs into scalable system solutions. Lead the analysis, documentation, and implementation of technical specifications while ensuring alig...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$103K - $134K *

Optimize enterprise Care Delivery & Imaging applications, ensuring seamless integration and performance. Lead technical initiatives, support clinical operations, and enhance patient care through innov...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$78K - $97K *

Optimize pricing strategies by analyzing market trends and collaborating with teams to enhance competitive positioning and drive revenue. Leverage insights to recommend actionable solutions that align...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $155K *

Champion product innovation by managing software initiatives that enhance internal communication and streamline operations. Collaborate with cross-functional teams to deliver impactful solutions and d...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Staffing

$79K - $118K *

Champion exceptional geriatric care by providing comprehensive nursing services, coordinating patient treatment, and ensuring a safe, therapeutic environment for older adults in a collaborative, evide...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Inspire excellence in geriatric care by delivering compassionate, evidence-based nursing. Collaborate with a dedicated team to ensure holistic well-being and safety for older adults in a supportive en...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Shape the future of AI/ML systems by architecting scalable, high-availability platforms. Lead technical teams, establish standards, and implement best practices for enterprise-grade AI solutions that...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Staffing

$100K - $120K *

Drive the success of clinical trials by managing operations, ensuring compliance, and collaborating with cross-functional teams to achieve high-quality outcomes while adhering to budget and timelines...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Deliver exceptional clinical trial management by overseeing operations, ensuring adherence to protocols and standards, and fostering collaboration with diverse teams to drive high-quality outcomes acr...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Drive the design and implementation of data models using statistical and machine learning techniques. Collaborate with teams to analyze metrics and optimize product strategies, ensuring effective comm...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$79K - $122K *

Empower your career by developing innovative Microsoft 365 solutions. This role involves end-to-end Power Platform development, ensuring compliance, and collaborating with stakeholders to enhance city...

Durham, NCRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.