Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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1,000+

Healthcare Analyst Jobs in Missouri

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$70K - $137K *

Elevate agricultural finance research by leading the Early Warning System, engaging stakeholders, and developing analytical tools to assess farm financial conditions and risks, driving informed decisi...

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$125K - $150K *

Join a team that's driving enterprise growth in healthcare across the TOLA region. Leverage your strategic selling skills to open new accounts and build executive relationships, transforming patient e...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$107K - $199K *

Shape the future of Care Management solutions by leading strategic planning, defining product strategies, and collaborating with stakeholders to enhance healthcare delivery and profitability...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$192K - $334K *

Tackle complex healthcare M&A engagements, leading due diligence efforts, and collaborating with clients and teams to drive value. Manage multiple projects while utilizing your expertise to influence...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$119K - $179K *

Support the integration and harmonization of clinical data by designing FHIR-compliant models and pipelines, ensuring data accuracy and usability for patient care and research initiatives across the o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$93K - $140K *

Accelerate progress at defining technical requirements and solutions, collaborating with business experts to enhance operational processes. Lead projects, mentor analysts, and ensure alignment of tech...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $240K *

Optimize quality intelligence and root cause analysis initiatives to enhance audit quality. Lead data-driven insights and predictive risk assessments, collaborating with stakeholders to identify trend...

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$75K - $90K *

Lead the charge in driving sales growth by engaging independent physician practices. Utilize your expertise in full-cycle sales to build relationships, conduct virtual demos, and collaborate with team...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $97K *

Shape the future of marketing analytics by building robust data pipelines and automating reporting workflows. Collaborate with cross-functional teams to enhance data quality and leverage AI tools for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$250K - $300K *

Champion strategic growth by leading the charge to secure complex health system accounts. Drive transformative deals with hands-on coaching, leveraging deep relationships and expertise to elevate team...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Champion the management and execution of complex e-discovery projects, collaborating with legal teams to ensure successful outcomes. Oversee multiple projects while mentoring a team, maintaining quali...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$150K - $160K *

Lead the charge in executing population health strategies, ensuring high-quality consulting delivery and team performance across regions. Collaborate with leadership to drive impactful solutions and f...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock potential by providing senior-level analyst support for complex provider reimbursement activities. Collaborate with stakeholders to implement and maintain reimbursement methodologies across var...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower your career as a Data Advisor, driving data integrity and operational excellence in security reference data and pricing. Collaborate across teams to enhance processes and support strategic ini...

5 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Shape and execute a comprehensive partnership strategy to drive growth, enhance market presence, and foster high-value alliances across the healthcare ecosystem, collaborating with executive leadershi...

United StatesRemote

5 days ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Lead the execution of clinical trials by monitoring site activities, ensuring compliance with regulations, and collaborating with teams to achieve study objectives. Play a key role in training site st...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Unlock potential by leading compliance audits, ensuring accurate coding and documentation in anesthesia. Collaborate with teams to mitigate risks, deliver training, and maintain regulatory standards w...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $210K *

Lead the charge in advancing strategic partnerships with health plans. Shape and optimize BetterHelp’s payer strategy, enhance agreements, and identify growth opportunities while collaborating across...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$107K - $172K *

Shape the future of cash management by enhancing forecasting capabilities and providing critical insights for strategic decision-making, operational planning, and capital allocation in a dynamic envir...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$124K - $155K *

Champion data-driven insights as you lead a multidisciplinary analytics team, driving client performance and strategic recommendations to enhance business growth and market competitiveness...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $202K *

Create innovative AI-powered healthcare products by transforming complex workflows into intuitive applications. Collaborate with cross-functional teams to deliver impactful user experiences and own fe...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$102K - $190K *

Innovate data management processes by leading the development of robust data pipelines, ensuring high-quality data for analytics and reporting. Collaborate with cross-functional teams to enhance data...

Missouri, USRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K *

Engage with clients by leveraging data analysis and technical expertise to drive revenue growth. Collaborate with sales teams to ensure data accuracy and create tailored solutions, enhancing customer...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$121K - $161K *

Transform your career by leading the design and implementation of Veeva Vault RIM, ensuring optimal performance and compliance while collaborating with cross-functional teams to enhance user experienc...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$58K - $105K *

Unlock your potential by managing the full contracting lifecycle, supporting critical agreements for Medicare Advantage and Commercial operations, while collaborating with diverse teams to enhance com...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.