Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$138K - $201K *
Architect cloud-based data solutions and drive enterprise data strategy. Leverage advanced analytics and modern data architectures to enhance operational efficiency and compliance in healthcare data m...
3 weeks ago
$195K - $217K *
Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...
2 weeks ago
$88K - $121K *
Join a team that's redefining financial analytics by developing cutting-edge predictive models. Collaborate globally, analyze large datasets, and drive impactful solutions in the financial services in...
3 weeks ago
$120K - $155K *
Join a team that's dedicated to enhancing national security through expert program analysis. Leverage your extensive experience to support critical FAA initiatives, ensuring compliance and effective p...
5 days ago
Medicaid Certification Consultant
$70K - $120K *
Lead transformative Medicaid initiatives by guiding project oversight, ensuring timely execution, and enhancing stakeholder engagement. Collaborate with teams to streamline operations and achieve stra...
2 weeks ago
Senior Medicaid Technical Business Analysis Engineer
$81K - $105K *
Analyze Medicaid operations and claims processing to drive system solutions. Collaborate with stakeholders to enhance efficiency and compliance while addressing complex business challenges in a fast-p...
Yesterday
Senior Strategy & Analytics Advisor, C&CE - Evernorth - Remote
$112K - $188K *
Join a team that's shaping customer experience through data-driven insights. Lead analytical projects that enhance operational efficiency and drive strategic improvements, collaborating with leadershi...
3 weeks ago
Senior Strategy & Analytics Advisor, C&CE - Evernorth - Remote
$112K - $188K *
Transform customer experiences by leading strategic analytics initiatives that drive operational efficiency and enhance associate capabilities. Collaborate with leadership to develop insights and infl...
3 weeks ago
Senior Project Manager - U.S. Healthcare Programs
$110K - $130K *
Champion the end-to-end management of complex healthcare programs, ensuring operational readiness and compliance. Collaborate with teams and clients to drive successful implementations while maintaini...
6 days ago
SENIOR KNOWLEDGE MANAGEMENT ANALYST
$87K - $135K *
Unlock your potential by leading a dynamic Knowledge Management program that enhances IT support services, fosters collaboration, and drives efficiency for a large-scale enterprise environment. Make a...
2 weeks ago
Senior Specialist, Epic Solution Delivery (Ambulatory)
$110K - $130K *
Lead the charge in Epic solutions delivery by providing expert support, managing projects, and mentoring team members. Shape the future of healthcare IT by aligning technical teams with stakeholder ne...
Reposted 5 days ago
$74K - $91K *
Contribute to national health data collection efforts by leveraging your nursing expertise and survey research skills. Engage in participant-centered data collection, quality control, and training whi...
5 days ago
$80K - $95K *
Unlock insights by leading advanced data analytics for federal programs. Collaborate with cross-functional teams to ensure compliance and data integrity while mentoring junior analysts and presenting...
1 week ago
$88K - $118K *
Join us to analyze and document business and technical requirements, implement process improvements, and support ERP projects. Collaborate with teams to ensure accurate reporting and optimize system s...
1 week ago
$75K - $135K *
Unlock the potential of secure application access by providing engineering support, troubleshooting connectivity issues, and collaborating with teams to enhance service reliability and customer experi...
1 week ago
Myna Account Executive, Healthcare and Dental
$100K - $120K *
Join a team that's transforming healthcare with AI solutions. Drive full-cycle sales, engage decision-makers, and exceed quotas while improving patient access and operational efficiency in dental and...
Today
Myna Account Executive, Healthcare and Dental
$100K - $120K *
Join a dynamic sales team to drive AI-powered solutions in healthcare. Engage with decision-makers, uncover challenges, and demonstrate Myna's value to enhance patient access and streamline operations...
Today
Pharmacist Clinical - Institutional
$95K - $115K *
Make your mark at a dynamic healthcare facility, providing essential pharmaceutical care, verifying medication orders, and collaborating with healthcare teams to enhance patient safety and treatment e...
Today
Credentialing & Payor Enrollment Supervisor
$69K - $104K *
Lead and enhance credentialing and payor enrollment operations, ensuring compliance and accuracy while supervising specialists and streamlining processes to improve provider readiness and operational...
Reposted 3 days ago
Account Executive - Healthcare
$200K - $255K *
Elevate your career by driving new business in healthcare accounts. Engage with C-level executives, navigate complex sales cycles, and close high-value deals to expand market presence and achieve reve...
Reposted today
Workday Systems Analyst - Benefits & HCM
$105K - $142K *
Partner with us to drive system design and support for Talent Management. Leverage your Workday expertise to analyze functionality, mentor team members, and lead complex projects while enjoying a coll...
2 weeks ago
Workday Systems Analyst - Benefits & HCM
$105K - $142K *
Engage as a key technical consultant, driving Workday system design and support for Talent Management. Collaborate with teams to analyze needs, implement solutions, and enhance functionality while men...
2 weeks ago
Workday Systems Analyst - Benefits & HCM
$105K - $142K *
Unlock potential by driving Workday system design and support for Talent Management. Collaborate with teams to analyze needs, implement solutions, and enhance functionality while mentoring others in a...
2 weeks ago
Workday Systems Analyst - Benefits & HCM
$105K - $142K *
Shape the future of our HR systems by driving Workday design, development, and support. Collaborate with teams to enhance functionality, mentor peers, and deliver innovative solutions that meet user n...
2 weeks ago
Director, Insights and Analytics
$150K - $180K *
Optimize your career by leading insights-driven strategies that shape brand decisions. Collaborate across functions to deliver actionable market research and analysis, driving impactful outcomes in a...
4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.