Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$90K - $110K *
Analyze healthcare data to enhance clinical insights and improve medication use. Collaborate with cross-functional teams to develop analytics tools and real-world evidence studies, driving better heal...
1 week ago
$102K - $138K *
Lead the charge in delivering actionable insights through advanced analytics, supporting employer group partners with healthcare claims and utilization data. Collaborate across teams to enhance report...
2 weeks ago
Data Analyst (Healthcare Data Analytics)
$80K - $115K *
Analyze and enhance client data reporting, driving insights and trends to support customer satisfaction and business growth. Collaborate with cross-functional teams to ensure data integrity and delive...
3 weeks ago
$70K - $105K *
Engage in strategic healthcare analytics to enhance operations, improve reimbursement processes, and drive data-driven insights. Collaborate cross-functionally to optimize quality and financial perfor...
Reposted 2 weeks ago
$70K - $126K *
Analyze program outcomes and collaborate with stakeholders to enhance results. Manage complex projects, provide insights to leadership, and educate agencies on best practices to optimize performance a...
Reposted 2 days ago
Data Analyst, Clinical Data Effectiveness
$95K - $115K *
Analyze and optimize the clinical data lifecycle, ensuring data completeness and integrity. Collaborate cross-functionally to enhance clinical data flows and vendor strategies, driving quality improve...
Reposted yesterday
$85K - $100K *
Drive your career with a pivotal role in optimizing Epic Willow Ambulatory applications, enhancing pharmacy operations through strategic collaboration, innovative solutions, and robust system manageme...
Reposted today
Application Analyst, PB Claims and Remittance
$80K - $95K *
Manage and optimize Epic Professional Billing workflows, focusing on Claims and Remittance. Serve as a key resource for end-users, troubleshooting issues and enhancing billing processes to ensure accu...
4 weeks ago
$66K - $114K *
Champion the analysis and development of actuarial data to support Medicaid pricing. Collaborate with teams to refine models and ensure data accuracy, while gaining valuable experience in a dynamic, h...
3 weeks ago
$94K - $164K *
Unlock potential by leading research and analysis to identify system impacts, dependencies, and business needs. Collaborate with stakeholders to enhance processes and deliver clear requirements in a d...
3 weeks ago
$80K - $95K *
Transform patient access by optimizing Epic Cadence workflows. Collaborate with clinical teams to enhance scheduling efficiency and support system improvements, ensuring seamless operations and superi...
1 week ago
$80K - $95K *
Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...
3 weeks ago
Hospital Coding Quality Integrity Analyst - Inpatient
$73K - $110K *
Drive coding quality and compliance by analyzing data, supporting audits, and enhancing documentation practices. Collaborate with teams to ensure accurate coding and adherence to regulatory standards...
1 week ago
$92K - $126K *
Drive innovative solutions by blending product analytics and low-code development, collaborating cross-functionally to enhance AI Agent capabilities and optimize Revenue Cycle operations within the he...
Reposted 1 week ago
$76K - $90K *
Join a team that's enhancing healthcare through expert support of EHR systems. Lead optimization initiatives, mentor junior analysts, and collaborate with diverse teams to improve clinical and operati...
Reposted 4 weeks ago
Lead Analyst, Business Intelligence
$111K - $167K *
Join a dynamic team as a strategic analytics partner, driving insights and performance improvements across revenue cycle operations. Collaborate with leaders to define KPIs, analyze data, and create i...
1 week ago
Senior Business Systems Analyst - Healthcare Payor Specialized
$81K - $142K *
Lead the design and development of enterprise data management solutions, collaborating with stakeholders to analyze requirements and enhance data processing capabilities using advanced technologies in...
1 week ago
Applications Analyst-Clinical-Sr
$89K - $136K *
Innovate clinical application support to enhance patient care efficiency. Manage software upgrades, coordinate with IT teams, and lead projects while ensuring compliance and effective communication ac...
5 days ago
$80K - $95K *
Join a team that's driving innovation in actuarial analysis. You'll tackle complex projects, conduct risk assessments, and mentor junior analysts, all while collaborating in a dynamic hybrid work envi...
Reposted 4 days ago
$80K - $95K *
Engage in complex actuarial projects, analyzing risk contracts and training junior staff. Collaborate on pricing and management reports to support innovative capitation initiatives, fostering a dynami...
4 days ago
DRG Quality Analyst IV - Healthcare
$85K - $110K *
Optimize clinical DRG audits by ensuring accuracy and consistency in coding. Mentor auditors, recommend process improvements, and conduct quality reviews to enhance performance and compliance in a rem...
1 week ago
$75K - $110K *
Join us to develop scalable analytics and reporting solutions that drive business decisions. Collaborate with teams to enhance data quality and automate processes, turning insights into impactful acti...
Reposted today
$85K - $100K *
Join our dynamic team to analyze and enhance ACO performance in Medicare VBC programs. Leverage your expertise in data analytics to drive insights, track KPIs, and support data-driven decision-making...
4 days ago
$100K - $120K *
Join us to empower community coalitions in preventing youth substance use. As a Project Officer, you'll manage grants, provide technical assistance, and enhance local capacities, all while collaborati...
6 days ago
$90K - $110K *
Analyze and optimize public health programs by coordinating project activities, evaluating operational enhancements, and ensuring compliance with regulatory standards to improve health outcomes for af...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.