Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$110K - $130K *

Engage in a dynamic role leading security operations and AI integration. Oversee real-time threat monitoring and incident response while developing automated workflows in a cutting-edge, multi-tenant...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$85K - $90K *

Elevate community engagement by building trusted relationships with senior living staff and residents. Act as a vital connector, ensuring seamless access to on-site care services while fostering colla...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$91K - $151K *

Shape the future of public health by leading the development of a statewide vaccine management and clinical case management system, ensuring seamless integration and support for local health departmen...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$113K - $197K *

Drive automation and AI initiatives in claims operations, enhancing efficiency and accuracy. Lead a team to optimize workflows, manage vendor performance, and ensure compliance while delivering measur...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Oversee consulting engagements to assess risks in processes and controls. Act as a subject matter expert in financial, operational, and IT audits, providing advisory services and enhancing audit funct...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$186K - $233K *

Empower the future of real-world analytics by leading programming activities for observational studies, ensuring high-quality deliverables through collaboration with cross-functional teams and innovat...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$156K - $227K *

Champion executive compensation strategies that align with business objectives. Lead the design and execution of Total Rewards programs, provide expert consultations, and drive cross-functional collab...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $135K *

Advance educational research by analyzing data and synthesizing findings to enhance student access to advanced courses. Collaborate with stakeholders to design studies, build dashboards, and communica...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $192K *

Drive the expansion of revenue cycle workflow products, collaborating across teams to define business requirements, develop product roadmaps, and ensure effective delivery using Agile methodologies fo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Join a team that's driving regional marketing initiatives in hematology and oncology. Engage with key thought leaders, execute strategic plans, and leverage local opportunities to enhance brand presen...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Champion quality performance initiatives by collaborating across departments to enhance healthcare outcomes through data analysis, project management, and compliance with regulatory standards, ensurin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $212K *

Elevate AI security by designing robust frameworks to protect systems from threats. Collaborate with cross-functional teams to ensure compliance and ethical use, while implementing strategies that saf...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $117K *

Drive impactful digital health solutions across multiple countries, enhancing health systems and capacity building. Collaborate with diverse teams to implement strategies that ensure sustainable healt...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$182K - $198K *

Build and lead a robust Service Management Office to enhance IT operations, ensuring effective governance, accountability, and continuous improvement across a complex 24x7 environment, while fostering...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Join a team that's shaping the future of clinical utilization management. As a clinical expert, you'll engage with healthcare professionals to optimize specialty medication management and enhance pati...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $231K *

Unlock potential by leading strategic capture management initiatives, collaborating with cross-functional teams to enhance proposal quality and win probability in Medicaid managed care. Drive innovati...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$65K - $109K *

Partner with us to foster strategic relationships, optimize account performance, and drive engagement with key stakeholders, leveraging your knowledge of healthcare technology to deliver impactful sol...

RemoteRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Join a dynamic emergency medicine team at a top-rated hospital, providing high-quality care in a collaborative environment. Leverage your skills in a supportive setting while making a meaningful impac...

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Elevate compliance standards by coordinating and executing key program elements, advising on policies, delivering training, and managing compliance risks, ensuring an ethical culture and integrity in...

RemoteRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$163K - $220K *

Shape the future of healthcare by leading analytics for managed care, driving payer strategies, and delivering insights to enhance access to medical benefit products. Collaborate with cross-functional...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Shape the future of healthcare by leading a dynamic sales team to forge vital partnerships with medical providers, enhancing patient access to behavioral health services through innovative strategies...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $170K *

Join a team that drives modern security practices by prioritizing data exposure risks. As an expert in databases and data stores, you'll identify vulnerabilities and collaborate with teams to mitigate...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Advance client relationships and team performance as a strategic leader, overseeing captive insurance operations, driving excellence, and enhancing service delivery while managing complex engagements...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Help us shape innovative solutions by applying your software expertise and problem-solving skills. Your role is crucial in developing high-quality applications in a collaborative, agile environment, a...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.