Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$85K - $111K *

Advance your career by leading the Claims Domain for MMIS health care projects. Drive analysis, documentation, and quality processes while collaborating with clients and development teams to meet cust...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$157K - $256K *

Champion strategic engagements with oncology thought leaders to enhance insights and drive initiatives for our Solid Tumor portfolio, focusing on collaboration across teams and executing regional stra...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Help us lead complex federal grant management projects, mentor teams, and ensure compliance while supporting clients in diverse sectors. Drive business development and contribute to thought leadership...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$160K - $200K *

Transform the communications landscape by building a dynamic team that drives brand relevance through strategic earned media, influencer relations, and corporate communications, ensuring a consumer-fi...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$200K - $250K *

Empower growth in the cybersecurity sector by driving sales, acquiring new accounts, and fostering strong customer relationships. Leverage your expertise to introduce innovative solutions and exceed s...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Partner with us to drive transformative healthcare solutions by managing key accounts, fostering relationships, and ensuring measurable outcomes. Your expertise will enhance provider partnerships and...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Healthcare

$240K - $269K *

Advance your career by leading national account strategies in oncology, fostering relationships with health plans and PBMs. Drive coverage, reimbursement, and adoption initiatives while collaborating...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$122K *

Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Execute comprehensive project controls to ensure timely, budget-compliant project completion. Collaborate with teams to analyze financial data, manage forecasts, and report on project progress across...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$115K - $135K *

Drive your career forward by managing a diverse portfolio of high-net-worth clients, delivering expert tax preparation and advisory services while collaborating with financial advisors to maximize cli...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Manage a team of engagement managers to enhance operational effectiveness, drive project execution, and implement innovative solutions. Oversee financial performance and resource allocation while fost...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Join a team that's dedicated to enhancing community health by providing comprehensive dental care, leading a skilled team, and promoting oral health education while ensuring a positive patient experie...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$63K - $97K *

Support clinical trial operations by monitoring lab services, engaging with sites, and ensuring compliance with regulations. Collaborate with teams to enhance processes and deliver timely results for...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$134K - $219K *

Empower data management excellence by leading cross-functional teams, ensuring compliance, and driving process improvements across multiple clinical trials while mentoring staff and maintaining high d...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$83K - $95K *

Engineer secure enterprise infrastructure by designing, implementing, and maintaining robust security measures across on-premises and cloud environments, ensuring compliance with industry standards an...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Join our dynamic emergency medicine team to deliver exceptional patient care in a fast-paced environment. Collaborate with skilled professionals and enhance your career while making a meaningful impac...

6 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$119K - $186K *

Lead and manage multiple accreditation projects, ensuring high-quality client deliverables. Collaborate with consulting professionals to enhance service delivery and develop innovative solutions in he...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$275K - $350K *

Lead the charge in transforming operations by integrating AI and technology to enhance member and clinician experiences, ensuring efficient care delivery and operational excellence across a distribute...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $105K *

Unlock potential by leading life underwriting transformation initiatives. Drive strategic projects and process improvements that enhance efficiency and operational effectiveness while collaborating ac...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$126K - $210K *

Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$210K - $250K *

Drive growth and innovation in clinical development, leading cross-functional teams to enhance therapeutic portfolios, particularly in cell and gene therapy, while ensuring medical oversight and strat...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive the growth of a therapeutic portfolio by leveraging medical expertise and overseeing clinical trials. Collaborate across teams to shape strategies in cell and gene therapy, ensuring innovative...

Covington, KYRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $232K *

Engage with key health-plan relationships to drive revenue retention and growth. Oversee a strategic portfolio, leveraging analytics and executive relationships to enhance member access and operationa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Join a team that's redefining financial strategies. As a Senior FP&A Analyst, you will lead R&D budgeting, forecasting, and variance analysis, impacting vital business decisions while collaborating wi...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.