Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$88K - $105K *

Drive the regional sales strategy for specialty medications in Oncology, fostering relationships with healthcare providers and maximizing referral potential through effective communication and support...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Champion regional sales strategies to enhance specialty medication adoption in Oncology. Engage with healthcare providers, analyze performance metrics, and build strong relationships to drive impactfu...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Champion the regional sales strategy for specialty medications in Oncology, driving adoption and utilization through strong relationships and effective communication with healthcare providers across y...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$115K - $158K *

Pioneer the enterprise-wide adoption of Agile methodologies by coaching Agile Release Trains and Scrum teams. Drive effective practices, enhance collaboration, and foster continuous improvement across...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage energy strategies and operations for multiple facilities, ensuring optimal performance of the Central Energy Plant. Mentor staff, oversee maintenance, and implement best practices to enhance en...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$202K - $257K *

Empower growth by identifying opportunities and aligning technical strategies with customer goals. Lead solution discussions with executives, drive innovation, and mentor teams to enhance knowledge an...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$175K - $250K *

Drive the development of innovative reinsurance strategies and statutory capital optimization. Lead cross-functional teams to enhance corporate solvency and risk-adjusted returns while managing regula...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Lead pharmacy benefit strategies and analytics, driving client success through innovative solutions and partnerships. Collaborate with teams to enhance operational efficiency and mentor colleagues whi...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$163K - $204K *

Unlock potential by leading innovative machine learning methods for cancer detection, collaborating with experts, and mentoring junior scientists to advance research in multi-cancer early detection us...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$156K - $215K *

Shape the future of enterprise Quality Engineering by leading automation tools and onboarding initiatives. Drive best practices, enhance tool adoption, and optimize testing solutions to improve delive...

RemoteRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Healthcare

$105K - $126K *

Lead and optimize subcontract management by negotiating agreements, ensuring compliance, and collaborating with stakeholders to drive successful federal contracting outcomes while mentoring junior sta...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $129K *

Accelerate progress at a growing company by transforming data into strategic insights, enhancing sales efficiency with automated reporting, and driving data-driven improvements across teams to support...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$65K - $101K *

Join a team that's dedicated to enhancing knowledge management by creating impactful documentation, analyzing user feedback, and developing chatbot content for an enterprise IT Customer Support Servic...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$280K - $300K *

Advance your career with a high-impact sales role focused on driving new business and expanding relationships within large enterprise accounts, leveraging cutting-edge AI technology to deliver measura...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$189K - $315K *

Lead the charge in transforming Oncology Field Access & Reimbursement strategies, coaching a dedicated team to enhance patient access and engagement across the East region while ensuring compliance an...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $155K *

Lead validation efforts for complex GxP computerized systems, ensuring compliance and quality. Collaborate with IT and QA, mentor junior staff, and execute risk-based project strategies to maintain in...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Deliver exceptional patient care by leading a collaborative team in a dialysis facility. Oversee clinical operations, ensure compliance, and drive quality improvement while fostering staff development...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Lead the future of asset-based field examinations by delivering insightful analyses, evaluating financial controls, and ensuring compliance. Collaborate with clients to assess collateral values and mi...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$106K - $160K *

Join our team as we optimize IT demand management by coordinating technology requests, ensuring alignment with strategic goals, and enhancing service delivery across the organization. Your expertise w...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Explore innovative strategies for organizational change management, driving successful project transitions and integrating emerging technologies while ensuring effective communication and collaboratio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Empower growth by leading private equity partnerships, driving telehealth solutions across portfolios. Build relationships, negotiate agreements, and create a repeatable deployment model to enhance he...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$121K - $167K *

Lead the evolution of real estate applications by designing and implementing innovative technology solutions, enhancing system reliability, and driving proactive support across Yardi platforms and int...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Shape the future of secure software development by integrating security practices into engineering workflows, building automation tools, and conducting penetration tests to identify vulnerabilities an...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $275K *

Advance the Data & Distribution Partnerships function by innovating and scaling data reseller and distribution models, building commercial arrangements, and leading a team to create revenue-generating...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $160K *

Empower the development of mission-critical applications on the ServiceNow platform, collaborating with stakeholders to deliver scalable solutions while ensuring compliance with federal standards and...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.