Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$98K - $132K *

Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in transforming healthcare analytics by building robust data models and dashboards. Collaborate with diverse stakeholders to deliver actionable insights, ensuring data quality and clar...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Join a dynamic team as you analyze business challenges, gather requirements, and collaborate with technical teams to deliver user-centered solutions in regulated environments, driving continuous impro...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$70K - $100K *

Join a team that's committed to financial excellence, ensuring accuracy and compliance in accounting operations. Lead month-end closes, enhance reporting, and drive process improvements while mentorin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Drive excellence in surgical care by leading clinical operations, ensuring integrated patient-focused services, and collaborating with healthcare teams to enhance outcomes and efficiency within the Su...

5 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Transform virtual primary care by delivering exceptional patient care in a collaborative environment. Join a dedicated team for a 5-month full-time opportunity, enhancing your skills while making a me...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Grow your career with a licensed mental health professional role, providing telehealth services across Kentucky. Conduct assessments, develop treatment plans, and facilitate therapy sessions in a supp...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Engage as a licensed mental health professional providing telehealth services. Conduct assessments, develop treatment plans, and facilitate therapy sessions in a secure virtual environment, ensuring q...

Nicholasville, KYRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$227K - $341K *

Lead the strategic development and continuous improvement of clinical programs, focusing on optimizing patient care across the continuum. Oversee a multidisciplinary team to enhance outcomes, reduce h...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $155K *

Accelerate the evolution of data analytics by leading modernization efforts, optimizing reporting capabilities, and fostering strategic partnerships across functions to drive data-driven decision-maki...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform budget planning and execution within clinical informatics, leveraging expertise in PPBE and MFR practices. Collaborate with leadership to ensure financial strategies align with healthcare in...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $126K *

Join a team that drives quality improvement initiatives in healthcare, ensuring compliance with regulatory standards. Lead complex projects, assess program effectiveness, and collaborate to enhance he...

RemoteRemote

Reposted 4 days ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $87K *

Transform customer experiences by leading Unanet ERP implementations, ensuring successful configurations and training for Government Contracting clients. Manage multiple projects, driving adoption and...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$225K - $281K *

Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$225K - $281K *

Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive strategic physician relationships to enhance referrals and promote specialty services. Manage territory initiatives and communicate essential market intelligence to increase volume, ensuring ali...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$147K - $217K *

Lead transformative analytics initiatives in life sciences, driving innovation and client success. Mentor teams, enhance measurement standards, and collaborate cross-functionally to deliver actionable...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$70K - $110K *

Join a team that's dedicated to supporting disaster recovery efforts. Collaborate with leadership and clients to navigate complex recovery operations, ensuring effective management of multi-billion do...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$144K - $288K *

Drive excellence in Solutions Delivery by leading client engagements, ensuring timely execution, and fostering strategic partnerships to enhance operational scalability and client satisfaction across...

RemoteRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$106K - $145K *

Join us to lead the development of innovative software solutions for the healthcare industry, ensuring high-quality standards and security practices while collaborating with global teams to solve comp...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$106K - $145K *

Pioneer innovative software solutions in healthcare, leading development efforts and collaborating with global teams to create high-quality, secure applications using modern technologies and practices...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $374K *

Unlock potential by leading medical management initiatives remotely, supporting member needs and optimizing clinical services for optimal care. Leverage your expertise in Orthopedic Spine or Neurosurg...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$102K - $182K *

Lead the design and delivery of innovative clinical sales training programs for Structural Heart, enhancing sales team effectiveness and product knowledge through strategic curriculum development and...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $360K *

Lead the charge in advancing oncology diagnostics by engaging community oncologists, driving medical strategy, and executing initiatives across a defined region in this impactful, field-based leadersh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.