Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$109K - $182K *

Optimize patient care by designing and evaluating pharmacy plans, ensuring safe medication use, and educating patients and staff in a home care setting. Collaborate with healthcare teams to enhance pa...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform numerical capabilities by developing innovative algorithms and solutions, engaging in model building, and collaborating with software teams to enhance product performance and deliver impactf...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $235K *

Transform healthcare operations by partnering with client leaders to ensure effective Revenue Integrity during Epic implementations. Leverage your expertise to drive informed decisions and optimize re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Shape the future of data governance by leading methods and standards across enterprise systems. Collaborate with teams to define quality rules and documentation, ensuring consistency and excellence in...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $100K *

Empower our mission by ensuring cybersecurity compliance and risk management for the Veterans Health Administration's Enrollment System. Collaborate with stakeholders to maintain security documentatio...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$79K - $142K *

Elevate data-driven decision-making by transforming HR data into strategic insights. Leverage analytical skills and tools to enhance workforce performance and support HR initiatives, ensuring data acc...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$90K - $110K *

Transform patient care by delivering comprehensive medical services as part of an integrated team. Collaborate with physicians to implement treatment plans and ensure high-quality health standards for...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $270K *

Unlock your potential by managing ML systems at scale, ensuring uptime and observability. Collaborate on deploying and scaling models, while enhancing platform reliability through advanced engineering...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$101K - $152K *

Champion innovative solutions by leveraging Epic expertise to enhance operational efficiency and drive strategic initiatives across healthcare environments, ensuring high-performance standards and cli...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Champion enterprise data architecture by establishing standards and a unified data catalog. Collaborate across teams to define metrics and ensure data governance, driving alignment and clarity in a ha...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Unlock potential by leading sales strategies that drive revenue growth, collaborating with experts to execute impactful cycles, and consistently achieving quotas in a dynamic market focused on health...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $138K *

Lead client provisioning operations in Revenue Cycle Management, ensuring secure and efficient access throughout the user lifecycle. Collaborate with cross-functional teams to enhance service delivery...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Shape the future of API management by designing and deploying robust solutions across diverse environments, ensuring seamless integration and operational excellence while mentoring clients to maximize...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$157K - $232K *

Lead the charge in building scalable data infrastructure for analytics. Collaborate with cross-functional teams to enhance data architecture, drive AI/ML initiatives, and establish governance across t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's shaping financial strategy in a high-growth tech environment. Own FP&A for one of the company's core areas, providing insights into forecasting, budgeting, and operational decisions...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Unlock potential by leading product marketing initiatives that empower healthcare teams. Drive sales enablement, module marketing, and customer expansion, while shaping messaging and content that reso...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $97K *

Manage member-centered care transitions by assessing needs, coordinating services, and connecting resources. Ensure safe discharges and follow-ups to reduce healthcare costs and improve outcomes for d...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Pioneer innovative solutions by leading client engagements with top firms. Drive discovery, connect needs to data insights, and collaborate across teams to deliver impactful results in a dynamic, remo...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$170K - $190K *

Transform data into actionable insights by leading a team of data scientists and analysts. Drive advanced analytics initiatives, foster collaboration with stakeholders, and ensure high-quality deliver...

RemoteRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $120K *

Elevate clinical trial success by providing expert oversight and guidance. Collaborate with cross-functional teams to ensure compliance, quality, and timely execution of monitoring activities while fo...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $110K *

Unlock the potential of coding excellence by leading a remote team of medical coders, ensuring accurate and compliant code assignment to enhance patient care through innovative home-based healthcare s...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Healthcare

$127K - $187K *

Unlock potential by transforming data into actionable insights that drive strategic decisions in communications. Collaborate across teams to enhance measurement frameworks and reporting, ensuring impa...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $135K *

Join a team that's dedicated to enhancing federal cybersecurity compliance through advanced risk management and governance. Leverage your expertise to conduct assessments, manage authorizations, and e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$94K - $164K *

Champion cost reporting processes by ensuring data accuracy, preparing detailed reports, and analyzing financial information. Collaborate across departments to enhance reporting systems and support st...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.