Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$85K - $100K *

Join a dynamic team to lead physician practice operations, enhance patient care, and drive strategic initiatives. Oversee staffing, budgets, and compliance while fostering a collaborative environment...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$162K - $212K *

Bring your expertise to our Trade Surveillance team as you develop and enhance detection models to combat market abuse, ensuring integrity in trading partnerships and delivering precise, actionable in...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$167K - $191K *

Oversee the strategic development and execution of HEOR/RWE initiatives, collaborating with cross-functional teams to drive impactful asset strategies and communicate insights effectively for informed...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a dynamic team to oversee clinical research activities, ensuring compliance with regulatory standards and driving site performance. Collaborate with stakeholders to enhance patient safety and dat...

RemoteRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Transform data into actionable insights by owning the analytics pipeline from ingestion to visualization. Collaborate with cross-functional teams to create trusted models and metrics that empower deci...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$102K - $157K *

Unlock potential by driving new customer acquisition in healthcare. Engage C-suite leaders, champion innovative solutions, and lead complex sales cycles across AI and managed services to enhance patie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$149K - $248K *

Champion client engagement and operational excellence by managing consulting teams, driving quality standards, and fostering relationships within Military Health Systems. Lead new business development...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$166K - $250K *

Lead the charge in driving technical sales of innovative health solutions across payer and employer segments. Foster deep relationships and collaborate with teams to establish partnerships that genera...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$106K - $147K *

Lead the charge in developing innovative software solutions by collaborating with cross-functional teams, shaping product roadmaps, and delivering high-quality user interfaces and APIs that enhance us...

Kentucky, USRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$87K - $157K *

Unlock compliance excellence by managing auditing, monitoring, and reporting processes to ensure adherence to regulatory standards and enhance operational efficiency across contracts and collaboration...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $175K *

Empower scientific innovation by collaborating within product pods to develop and evaluate real-world evidence agents. Drive impactful research and ensure scientific rigor while partnering with indust...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Take ownership of designing, building, and maintaining critical IT system integrations, ensuring data flow and operational efficiency while troubleshooting complex issues and optimizing performance in...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$117K - $161K *

Empower our Quality Engineering operations by managing portfolio governance, financial planning, and resource allocation. Collaborate across teams to enhance transparency and execution, driving strate...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $161K *

Shape the future of Quality Engineering by leading portfolio management, financial governance, and strategic execution. Collaborate across teams to enhance operational effectiveness and drive transfor...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $149K *

Unlock potential by leading healthcare data analytics to enhance hospital quality performance and rankings. Collaborate with teams to design dashboards, mentor analysts, and present insights to execut...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$74K - $115K *

Join a dynamic team to develop and support SQL-based ETL processes, ensuring data quality and integration performance across business applications. Collaborate with technical teams to enhance data exc...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $100K *

Engage with healthcare teams to diagnose and treat diverse health conditions, ensuring comprehensive patient care through assessments, education, and management strategies in a supportive environment...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$195K - $341K *

Champion quality improvement initiatives by developing and implementing clinical care standards. Lead operational strategies, ensure compliance with regulations, and provide training and support to en...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by cultivating strategic relationships with benefits consultants and brokers. Drive revenue growth through effective partnerships, collaboration with cross-functional teams, and exper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to design and develop innovative automation solutions. Leverage your expertise in application development and automation tools to enhance efficiency and drive strategic goals withi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Elevate quality assurance in clinical audits by applying expert judgment and mentoring auditors. Ensure accuracy in DRG coding through comprehensive reviews and trend analysis, while fostering a colla...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$75K - $95K *

Optimize project outcomes by managing strategy and team engagement. Drive financial control and coordination of tasks to ensure timely delivery of high-quality results across print and digital channel...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.