Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$203K - $279K *

Drive strategic leadership for Medicaid utilization and care management. Lead development and execution of initiatives aimed at enhancing quality, access, and cost management while collaborating with...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$129K - $177K *

Lead the charge in designing and delivering AI capabilities for a platform, integrating advanced workflows and intelligent analysis while actively contributing to production code and managing a small...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$280K - $300K *

Drive new business growth by leveraging innovative automation solutions. Build lasting client relationships and serve as a trusted advisor in the Agentic Process Automation space, while exceeding sale...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to enhancing patient care through effective management and collaboration. As a key leader, you'll oversee personnel, coordinate resources, and support behavioral health st...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $144K *

Unlock your potential by driving marketing performance through data analysis, reporting, and strategic insights. Collaborate with cross-functional teams to enhance decision-making and optimize growth...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$100K - $120K *

Unlock your potential by driving strategic initiatives and M&A activities through in-depth research, analysis, and collaboration with senior leadership to inform corporate decisions and shape the comp...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower transformative telehealth solutions by designing and implementing robust software infrastructure. Join a dynamic team to innovate, automate, and streamline applications, impacting the healthca...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$100K - $125K *

Unlock potential by leveraging data to drive marketing strategies and insights. Collaborate with cross-functional teams to analyze customer behavior and quantify marketing impact, enhancing decision-m...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$69K - $101K *

Join us to enhance member health outcomes through holistic care management, collaborating with multidisciplinary teams to support individuals with complex needs. Utilize assessments and interventions...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$73K - $130K *

Lead the charge in overseeing claims compliance activities, enhancing operational quality, and ensuring audit readiness. Collaborate cross-functionally to identify gaps, monitor KPIs, and drive improv...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Join us to lead the development and execution of clinical study designs, ensuring effective project management and collaboration across teams. Your expertise will drive the success of clinical trials...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Unlock potential by driving analytics and AI solutions for clients, managing a $10M+ portfolio. Collaborate with sales teams to identify opportunities, build value stories, and achieve aggressive sale...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$114K - $140K *

Pioneer innovative solutions as a Data Scientist, driving advanced analytics and machine learning applications to enhance project success and economic opportunities across diverse teams and workflows...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$94K - $164K *

Empower healthcare outcomes by engaging in data analytics and reporting. This senior role manages complex datasets, collaborates with cross-functional teams, and creates dashboards to enhance operatio...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Oversee and enhance clinical operations, ensuring quality patient care and compliance. Lead and support clinical staff, manage documentation, and implement policies to achieve optimal outcomes in a ho...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $120K *

Advance your career by implementing innovative SaaS solutions, configuring custom workflows, and driving system integration projects. Collaborate with a dynamic team to tackle complex challenges and d...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Unlock potential by shaping innovative solutions for Opioid Treatment Programs and Medication Assisted Treatment. Collaborate with clients and teams to translate complex needs into actionable product...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Transform data into actionable insights by building robust data pipelines, dashboards, and monitoring frameworks. Leverage expertise in Skyline DataMiner to enhance network performance analytics and e...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Staffing

$195K - $341K *

Engage in clinical oversight and support staff training while ensuring adherence to quality standards and regulatory compliance in a collaborative healthcare environment focused on member care and ope...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$82K - $182K *

Take ownership of payer negotiation strategies and tools to enhance negotiation effectiveness. Translate market insights into actionable playbooks and frameworks that drive consistency, confidence, an...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize client success by leading strategic relationships and enhancing revenue cycle performance. Drive measurable improvements, manage escalations, and ensure value realization across healthcare so...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$184K - $396K *

Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$96K - $133K *

Support our cyber defense initiatives by leading incident response efforts, analyzing security events, and optimizing detection capabilities to enhance network security and protect sensitive data...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.