Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$110K - $120K *

Champion the development of high-quality program materials and deliverables, enhancing effectiveness in complex specialty markets. Collaborate with teams to ensure project success through strong manag...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$95K - $115K *

Empower patient care by delivering high-quality, compassionate support as a Hospitalist Nurse Practitioner. Collaborate with physicians and nursing teams to manage diverse patient needs during night s...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$75K - $90K *

Unlock potential by leading data analysis and storytelling efforts, ensuring insights meet client needs. Collaborate with teams to deliver actionable reports and maintain high-quality standards throug...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Business Services

$125K - $140K *

Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in managing and optimizing fundraising databases, ensuring data integrity and effective system use while collaborating with cross-functional teams to enhance donor engagement and suppo...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $175K *

Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Elevate operational efficiency by providing high-level administrative support to senior leadership, coordinating meetings, managing correspondence, and ensuring compliance with Navy directives while f...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$135K - $160K *

Join us to lead Oncology integrated solutions, collaborating across teams to design and implement strategic, client-focused approaches. Shape impactful proposals that drive growth and enhance patient...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $95K *

Join us to play a key role in enhancing patient care through effective case management. Collaborate with multidisciplinary teams to ensure smooth transitions and high satisfaction levels while prevent...

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$125K - $175K *

Transform client relationships by driving value and engagement in a fast-growing segment. Leverage product expertise to manage renewals and upsell opportunities while contributing to best practices wi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $120K *

Analyze data trends and support program oversight as a key team lead. Collaborate across multiple teams to enhance reporting and data quality, ensuring effective problem management and continuous impr...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $100K *

Grow your career with a role focused on delivering tailored clinical care, collaborating with interdisciplinary teams, and mentoring future leaders in behavior analysis while ensuring comprehensive su...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Transform the lives of pediatric learners by conducting assessments, crafting individualized treatment plans, and collaborating with a multidisciplinary team to deliver holistic care while mentoring e...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$63K - $114K *

Unlock your potential by supporting strategic projects and planning in health care. Collaborate with diverse teams to drive business goals, enhance analytical capabilities, and develop innovative solu...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Champion the management of clinical trial agreements, ensuring quality and timely execution while collaborating with cross-functional teams to resolve contract issues and enhance processes for assigne...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$160K - $180K *

Champion growth and satisfaction by managing key Ecosystem client relationships. Drive sales of innovative data solutions in Life Sciences, leveraging deep industry knowledge to meet client needs and...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $158K *

Champion operational excellence by leading facilities management across a multi-state portfolio. Drive strategic initiatives, optimize vendor performance, and implement scalable processes to support o...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $175K *

Unlock your potential as a Director, leveraging insights and expertise to guide clients in navigating complex SaaS negotiations and market trends, while driving impactful strategies that enhance busin...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$86K - $138K *

Lead actuarial initiatives by leveraging your expertise to analyze complex data, mentor junior staff, and develop innovative solutions that drive informed decision-making and enhance operational effic...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Transform identity and access management by executing daily operations, supporting AI tooling, and managing SaaS vendor administration. This role offers hands-on experience and a clear growth path tow...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...

RemoteRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $110K *

Advance your career by crafting high-level communications for federal oversight entities. Collaborate with a team to ensure clarity and consistency in executive correspondence, while managing tight de...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Empower our analyst relations program by managing evaluations, timelines, and coordination. Collaborate with stakeholders to ensure accurate, timely engagement and support market insights for strategi...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.