Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Project Management Jobs in South Dakota

Sort By: Relevance

$120K - $145K *

Transform the future of healthcare by bridging business and technical teams. Leverage your expertise to develop scalable solutions, drive product delivery, and enhance customer value through data-driv...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Drive your career with a leadership role overseeing satellite operations, ensuring mission success through effective scheduling, training, and ground system management. Lead a dedicated team in a dyna...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$149K - $248K *

Lead the transformation of Workday Financial Management, ensuring effective design and implementation across finance and enterprise processes. Collaborate with cross-functional teams to optimize ERP c...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$204K - $290K *

Lead the technical strategy of a dynamic team, ensuring high-quality project delivery while fostering collaboration across product development. Advocate for best practices in code and operational proc...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$152K - $173K *

Lead the transformation of identity lifecycle management by optimizing IAM processes, ensuring seamless integration with cloud-native solutions, and driving strategic initiatives that enhance security...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$145K - $160K *

Drive strategic initiatives by leading complex, cross-functional projects that align stakeholders and transform business priorities into actionable plans, ensuring successful execution across Revenue...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $165K *

Unlock product potential by spearheading a dynamic team creating innovative user experiences. Drive prototypes from concept to validation, ensuring alignment with customer needs through rapid iteratio...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive the evolution of the company's financial planning systems, ensuring seamless integration and delivery of accurate reporting cycles that enable strategic decision-making for senior leadership and...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Champion strategic sales transformation by leveraging data and insights to drive growth, optimize operations, and enhance decision-making across a global sales organization. Collaborate with leadershi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$178K - $261K *

Lead the charge in shaping a secure and seamless identity experience for millions globally. Drive strategy for authentication, account management, and recovery while collaborating across teams to prot...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $180K *

Champion a transformative product vision, leading cross-functional teams to drive strategic outcomes in a dynamic digital health environment. Shape the future of patient care and client experience whi...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Lead the charge in managing strategic client accounts, ensuring satisfaction and growth. Collaborate with teams to drive financial performance and deliver excellence while building trusted relationshi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $192K *

Drive the expansion of revenue cycle workflow products, collaborating across teams to define business requirements, develop product roadmaps, and ensure effective delivery using Agile methodologies fo...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$160K - $200K *

Join a team that's redefining IT leadership, ensuring robust security and operational excellence across global platforms while driving innovation and growth at scale through strategic technology solut...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Take ownership of a fully distributed engineering team, driving delivery, quality, and growth while fostering a culture of communication and continuous improvement. Collaborate with cross-functional p...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $150K *

Lead a distributed engineering team to deliver high-quality software solutions. Foster a culture of ownership and continuous improvement while collaborating with cross-functional partners to drive bus...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Support project delivery as an Associate Engagement Manager, collaborating with teams on Workday implementations and ensuring customer satisfaction while driving innovation and strategic growth in the...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$74K - $137K *

Drive client success by managing service delivery and support engagements, ensuring satisfaction and adherence to service level agreements while fostering strong relationships and optimizing operation...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Media

$150K - $180K *

Shape the future of governance by building and managing comprehensive GRC frameworks, ensuring regulatory compliance, policy library development, and strategic vendor risk management, while collaborat...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$138K - $173K *

Drive cross-functional collaboration to ensure high-quality software delivery. Lead and mentor a team of engineers while optimizing processes and fostering a culture of innovation and continuous impro...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$150K - $180K *

Elevate your career by partnering with the CEO to drive strategic initiatives, optimize operations, and enhance organizational effectiveness. You'll tackle complex challenges, support executive decisi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$180K - $200K *

Elevate your career by driving growth strategies that enhance lead generation for multiple brands. Collaborate with cross-functional teams to optimize acquisition channels and improve conversion rates...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$206K - $413K *

Join our team to lead in Physical Medicine and Rehabilitation, providing oversight, improving utilization, and guiding medical policy. Collaborate with staff and external partners to enhance healthcar...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$190K - $215K *

Champion the future of energy development by leading regional strategies, managing utility relationships, and driving contract negotiations. This role balances strategic oversight with tactical execut...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$164K - $205K *

Elevate scientific rigor in real-world evidence development. Collaborate with cross-functional teams to ensure agent conceptualization and evaluation meet scientific standards, driving impactful solut...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.