Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Manager, Accounting & Finance
$165K - $190K *
Lead the charge in shaping financial strategy and operations, overseeing accounting, financial planning, and analysis. Drive integration across revenue models while managing a skilled finance team to...
5 days ago
$150K - $180K *
Shape the future of billing operations by leading a team to enhance accuracy, timeliness, and efficiency. Drive process improvements, manage complex accounts, and collaborate across functions to resol...
3 days ago
Director, Rebate Product Program
$173K - $200K *
Elevate rebate product strategy by leading development, driving growth, and enhancing operational performance. Collaborate across teams to ensure compliance and deliver measurable outcomes that align...
2 weeks ago
Dakotas/Wyoming Area Operations Manager
$110K - $130K *
Lead the charge in driving operational excellence across Dakotas and Wyoming. Collaborate with diverse teams to implement strategic initiatives, enhance client relations, and foster an inclusive envir...
3 days ago
VP, Product Management - Core Lending
$187K - $300K *
Lead the charge in enhancing core lending products, owning product P&L, and driving competitive strategies. Collaborate across teams to deliver growth, optimize market positioning, and ensure complian...
Reposted 1 week ago
Director, Corporate Communications and Brand
$153K - $200K *
Lead the charge in shaping corporate communications and brand strategy, enhancing market presence and credibility. Collaborate with executives and teams to amplify messaging and drive impactful initia...
3 weeks ago
Managing Consultant, Safety and Reliability
$126K - $153K *
Transform healthcare safety by leading multi-hospital engagements, applying High Reliability Organization principles, and driving operational improvements to enhance patient care and trust across dive...
2 days ago
Managing Director, Investment Structuring
$215K - $320K *
Lead the execution of investment structuring strategies globally, managing complex initiatives and stakeholder relationships to enhance operational effectiveness and drive investment decisions that al...
3 weeks ago
Director - AI Digital Product Management - Commercial Value & Access
$199K - $269K *
Grow your career with a leadership role in AI Digital Product Management, driving strategy and innovation across a portfolio of AI products. Collaborate with cross-functional teams to deliver scalable...
2 weeks ago
Director, Infrastructure Engineering
$170K - $250K *
Help us build a high-performing infrastructure team that drives operational excellence and reliability. Lead a diverse group of engineers, manage budgets, and modernize technology while collaborating...
2 weeks ago
$110K - $130K *
Reimagine the landscape of regulatory compliance by guiding the development and implementation of extended producer responsibility programs, ensuring adherence to statutory requirements while collabor...
3 weeks ago
$95K - $110K *
Transform creative visions into reality by leading design projects, mentoring teams, and collaborating with clients. Drive strategic branding initiatives while ensuring high-quality deliverables in a...
3 days ago
$110K - $130K *
Drive our growth marketing strategy end-to-end, optimizing lead generation and performance campaigns to boost pipeline and revenue. Collaborate with Sales and Product teams, harness data insights, and...
3 weeks ago
$120K - $150K *
Transform subscription retention strategies to drive growth and revenue. Own metrics, analyze data, and collaborate cross-functionally to enhance customer experience and optimize retention initiatives...
4 days ago
Director, Financial Reporting & Accounting Policy
$240K - $300K *
Lead the financial reporting and accounting policy functions, ensuring accurate GAAP and SEC compliance. Collaborate with cross-functional teams to enhance reporting processes and maintain robust inte...
2 weeks ago
Supplier and Procurement Manager
$110K - $130K *
Drive procurement excellence by managing vendor networks and asset supply chains for remote work solutions. Collaborate across teams to ensure scalable, compliant, and efficient deployment strategies...
4 days ago
Senior Technical Program Manager
$200K - $220K *
Empower the future of financial operations by mastering money movement, ensuring seamless transactions and transparency. Collaborate with cross-functional teams to drive product success and enhance cl...
1 week ago
Manager, Workday Financial Systems and Innovation
$104K - $140K *
Transform financial systems by leading a high-performing team to enhance Workday Financials, ensuring operational excellence and strategic alignment with business goals while driving continuous improv...
1 week ago
Organizational Change Management Senior Analyst
$95K - $115K *
Explore innovative strategies for organizational change management, driving successful project transitions and integrating emerging technologies while ensuring effective communication and collaboratio...
3 weeks ago
$69K - $110K *
Elevate financial strategies by providing expert analysis and support for diverse teams, ensuring compliance and integrity in financial operations while driving impactful decision-making across conser...
Reposted 2 days ago
Revenue Cycle Management Transformation Manager
$78K - $113K *
Join us in transforming Revenue Cycle Management by leveraging analytical skills to enhance operational excellence across various RCM functions, driving process improvements and supporting financial p...
1 week ago
$125K - $138K *
Engineer operational excellence by leading the Problem Management team, driving post-incident processes, and fostering continuous improvement initiatives to enhance platform stability and customer exp...
1 week ago
$110K - $130K *
Oversee the design and development of clinical databases while ensuring project timelines and quality standards are met. Collaborate across teams to provide technical support and mentor team members...
Reposted 5 days ago
$170K - $213K *
Lead a dynamic team to drive growth and operational excellence across Financial Products. Translate strategy into actionable plans, enhance customer experiences, and foster talent development while ac...
1 week ago
Associate Director, Commercial Learning - Field Skills
$171K - $235K *
Shape the future of customer engagement learning for field teams, driving capability development, strategic alignment, and performance impact across commercial operations in the pharmaceutical sector...
3 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.