Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Product Manager (Athena)
$205K - $231K *
Champion the Athena member experience by leading cross-functional teams to enhance vulnerability management and remediation processes, ensuring a seamless workflow for enterprise customers in a fast-p...
1 week ago
People Systems and Solutions Manager
$188K - $235K *
Unlock potential by shaping and driving the People Systems roadmap, translating business needs into scalable processes, and managing technology vendors to enhance the employee lifecycle through innova...
1 week ago
$160K - $200K *
Join a team that's scaling global revenue operations. As a strategic partner to the CRO, you'll drive operational excellence, manage initiatives, and influence key decisions in a fast-paced environmen...
Reposted 3 weeks ago
Sr. Manager, Pricing and Deal Desk
$160K - $170K *
Shape the future of pricing strategy by leading complex deal governance and analytics. Collaborate across teams to enhance deal integrity and leverage AI-driven tools for efficient pricing models, ens...
3 weeks ago
Senior Director Customer Analytics & Insights EMD
$232K - $348K *
Elevate customer understanding by leading analytics teams to deliver actionable insights that drive strategic decisions and enhance customer experiences across diverse markets and stakeholders...
1 week ago
Product Manager, Onboarding and Growth
$110K - $130K *
Lead the charge in enhancing user onboarding and product adoption through deep analysis of customer journeys and designing impactful experiences that drive growth in a B2B SaaS environment...
Reposted 1 week ago
$110K - $130K *
Innovate the growth strategy for our impact-driven organization, leading teams in expanding revenue while effectively enhancing patient engagement and outcomes in underserved communities. Drive measur...
4 weeks ago
$128K - $192K *
The Workday Financials/Professional Services Automation Senior Principal Consultant is a dynamic professional responsible for leading Workday Professional Services Automation and Financials workstream...
Reposted 1 week ago
$119K - $150K *
Lead transformative design initiatives in complex environments, driving impactful solutions through collaboration with cross-functional teams. Embrace AI tools to enhance workflows and deliver user-ce...
2 weeks ago
$200K - $225K *
Manage the valuation process for private equity investments, ensuring accuracy and compliance. Collaborate with investment teams and external providers while leading initiatives to enhance valuation p...
1 week ago
Principal Product Builder, Data
$205K - $256K *
Transform your career by leading Apollo's data strategy, ensuring the highest quality B2B data for GTM success. Drive product vision, collaborate cross-functionally, and enhance customer experiences t...
4 days ago
$160K - $190K *
Empower nonprofit organizations to maximize their impact by leading product strategy and execution for innovative fundraising solutions. Drive growth through deep customer insights, collaborative part...
Reposted 1 week ago
Program Manager, Quality & Commissioning, NA
$120K - $130K *
Champion quality and commissioning excellence across diverse construction projects, ensuring compliance and safety while fostering collaboration among teams and stakeholders to drive impactful results...
4 days ago
Senior Director, Revenue Strategy
$160K - $200K *
Architect and lead revenue strategies, operations, and sales enablement to drive growth and enhance business performance, ensuring alignment across the GTM teams and fostering an innovative, collabora...
Reposted 1 month ago
Staff Product Manager, BioPharma Platforms
$146K - $224K *
Elevate clinical development by leading the strategy for biopharma platforms. Drive product lifecycles, collaborate with cross-functional teams, and ensure compliance while transforming workflows into...
1 week ago
Staff/Principal Product Manager, Patient Experience
$201K - $301K *
Optimize patient experiences by leading product strategy and execution across B2B2C healthcare environments, balancing client expectations with technical feasibility while driving innovation in AI-dri...
Reposted 1 month ago
Director, Process Optimization Lead
$171K - $231K *
Champion operational excellence and innovation within the P&SM function, driving strategic planning, resource management, and cross-functional collaboration to enhance efficiency in clinical study exe...
Reposted 1 week ago
Vice President Growth Marketing
$200K *
Lead the charge in driving enterprise growth marketing strategies, optimizing pipeline performance, and orchestrating cross-functional initiatives to scale demand generation and revenue outcomes acros...
Yesterday
Veeva CRM, Senior Manager - Organizational Change Management (OCM) - Remote, United States
$120K - $145K *
Lead the charge in organizational change management for complex life sciences transformations, focusing on global Veeva CRM implementations. Drive strategy, execution, and stakeholder engagement acros...
2 days ago
$119K - $142K *
Join a team that's redefining digital operations by leading strategic initiatives, enhancing customer experiences, and driving growth in a fast-paced environment. Shape the future of MODAL Digital whi...
2 weeks ago
Director of Performance Creative
$180K - $200K *
Unlock potential by leading a dynamic creative team to drive performance-focused video ads. Oversee the entire creative process, from concept to execution, ensuring data-driven decisions enhance custo...
1 week ago
$136K - $198K *
Champion analytics excellence by guiding clients and teams, leveraging deep expertise in Adobe Analytics to drive strategic decisions and enhance measurement practices in a fast-paced environment...
3 weeks ago
Senior Director, Cloud Operations
$150K - $180K *
Transform cloud operations by leading a team to ensure performance, reliability, and cost-efficiency across multi-cloud environments, while driving incident management and fostering collaboration with...
2 weeks ago
Product Manager, Pro Fulfillment
$142K - $183K *
Empower innovative product development that enhances user experiences and supports home service professionals. Drive impactful outcomes and challenge conventional thinking in a dynamic, user-focused e...
Reposted 3 weeks ago
Vice President, Financial Planning & Analysis
$145K - $270K *
Discover and lead the FP&A function, driving planning, forecasting, and performance management while partnering with executives to enhance financial outcomes and operational discipline across a dynami...
4 weeks ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.