Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$170K - $210K *

Drive excellence in design management for OFCI electrical systems in a hyperscale data center. Lead teams, enforce standards, and ensure seamless integration of owner-furnished equipment while managin...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$120K - $150K *

Drive new business growth by engaging scholarly publishers, managing the sales cycle, and collaborating with teams to tailor solutions that meet client needs. Leverage industry insights and strategic...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$97K - $190K *

Champion strategic sourcing in Design & Construction, leading procurement initiatives to optimize value and drive cost savings. Collaborate with stakeholders to enhance supplier relationships and ensu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$82K - $102K *

Join us to collaborate with a dynamic engineering team, managing projects from proposal to construction. Utilize your engineering expertise to deliver innovative solutions in structural design while f...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$165K - $175K *

Champion strategic people initiatives by advising leadership, crafting executive communications, and leveraging analytics to drive organizational effectiveness and accountability across the People fun...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $105K *

Transform client programs by overseeing delivery and optimization, ensuring alignment with objectives. Collaborate across teams to manage resources, timelines, and stakeholder expectations for success...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Drive the income tax provision process, compliance, and international tax reporting while enhancing internal controls in a lean tax department. Collaborate with cross-functional teams to optimize tax...

3 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$150K - $180K *

Join a team that's redefining audit practices by leading the transition to an agentic operating model. Collaborate across functions to innovate audit methodologies and drive transformation for clients...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $120K *

Empower your career by leading housekeeping operations across multiple properties. Drive quality, efficiency, and safety while collaborating with teams to enhance guest experiences and operational exc...

5 days ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$170K - $230K *

Elevate the sales strategy and operations by partnering with leadership to enhance productivity, implement AI solutions, and drive data-driven decision-making. Lead a team to optimize processes and en...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Champion the evolution of our billing systems by leading a dynamic engineering team. Drive strategy, ensure accuracy, and collaborate across departments to enhance customer trust as we scale our usage...

RemoteRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $163K *

Shape the future of AI in our organization as a strategic leader driving enterprise-wide adoption and integration of AI technologies, enhancing productivity and delivering measurable results through i...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Deliver strategic regulatory leadership for global development programs, overseeing regulatory strategy and execution from late-stage clinical phases to marketing authorization while ensuring complian...

North Carolina, USRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$165K - $248K *

Lead enterprise-scale operations for cloud services, ensuring performance and customer satisfaction. Drive a multidisciplinary team, manage service transitions, and leverage data-driven metrics to enh...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in managing and overseeing project portfolios, ensuring on-time, on-budget delivery while maintaining exceptional safety and service standards. Collaborate with teams and partners to d...

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

$155K - $306K *

Deliver impactful solutions as you lead AML Managed Services, ensuring compliance and quality across teams. Drive business development, oversee large-scale programs, and enhance financial crime compli...

5 days ago

  •   8 - 10 years exp.  •   Business Services

$80K - $90K *

Lead the visual narrative of client brands by delivering exceptional design solutions across multiple channels. Collaborate with diverse teams to uphold high standards and participate in innovative pr...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Innovate within a dynamic team to lead process design projects, ensuring compliance with cGMP and FDA standards while fostering client relationships and developing engineering talent for impactful sol...

3 days ago

  •   8 - 10 years exp.  •   Energy & Utilities

$133K - $235K *

Drive your career with impactful cross-functional programs, leading initiatives from planning to launch. Collaborate with diverse teams to navigate complexity, ensuring successful delivery and continu...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $145K *

Join a team that's driving innovation in product management, overseeing the entire lifecycle from strategy to commercialization. Collaborate with cross-functional teams to deliver impactful solutions...

4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Elevate client relationships as a strategic leader, driving retention and growth. Collaborate with cross-functional teams to deliver exceptional service and develop high-performing teams focused on cl...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$125K - $150K *

Join a dynamic team to enhance user experiences by managing product initiatives from discovery to launch, focusing on intuitive design and seamless integrations to improve data capture and conversion...

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$182K - $266K *

Partner with us to drive digital transformation and operational excellence across the ESS Group. Lead strategic technology initiatives, align IT with business goals, and enhance performance through in...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$144K - $288K *

Lead the digital product strategy for clinical documentation and care delivery, collaborating with multidisciplinary teams to enhance patient outcomes and streamline operations in outpatient settings...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$250K - $350K *

Empower enterprise clients by leading executive technology strategy, driving transformation initiatives that connect business priorities with major technology shifts, and building long-term, trust-bas...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.