Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Director, Market Growth Strategy, Molecule to Market (Biologics)
$185K - $256K *
Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...
1 week ago
Director, Chief of Staff for Hybrid Cloud COO
$146K - $353K *
Drive cross-functional execution and operational excellence as a trusted partner to senior leadership, enhancing visibility and resolving issues across engineering, product, and operations in a dynami...
Today
$163K - $224K *
Join a team that's redefining People Operations by leading global service delivery, enhancing employee experiences, and driving operational excellence across Talent Acquisition and People processes fo...
Reposted 1 week ago
$195K - $325K *
Unlock potential by driving AI solutions across diverse business units, identifying high-impact opportunities, and shaping strategic initiatives that enhance insights and decision-making processes glo...
5 days ago
$110K - $130K *
Join a team that's shaping the future of financial management in R&D. Drive project budgets, forecasts, and insights while collaborating with cross-functional teams to ensure financial efficiency and...
4 days ago
$105K - $125K *
Lead technology operations for global teams, optimizing systems and support. Collaborate on strategic AI solutions, ensuring compliance and enhancing workflows. Drive efficiency and innovation in a dy...
4 days ago
Director, Product Communications and Special Projects
$120K - $145K *
Transform complex organizational dynamics by designing strategic communication and operational frameworks for a large product team. Lead initiatives that align with overarching company goals, ensuring...
Reposted 3 weeks ago
$110K - $130K *
Elevate your career by leading Infor M3 ERP implementations. Drive project success through strategic planning, client management, and cross-functional collaboration while ensuring timely delivery and...
2 days ago
Assistant Commissioning Project Manager, PV - Southeast & Southcentral Region
$95K - $119K *
Drive the commissioning of renewable energy projects, managing teams to ensure all testing and installation meets safety standards and project goals. Collaborate across functions for seamless project...
Reposted 2 weeks ago
VP, Product Management, Profitability
$160K - $200K *
Transform product management in profitability by leading a team to innovate AI-driven solutions, enhancing revenue capture and client engagement across key platforms. Collaborate with cross-functional...
2 weeks ago
$149K - $224K *
Drive analytics excellence by leading a team to deliver impactful insights, enhance reporting capabilities, and support strategic decision-making across diverse business functions. Foster collaboratio...
2 days ago
$160K *
Drive innovative policy strategies for clean energy and electrification, managing a remote team of advocates while engaging diverse stakeholders to achieve ambitious multi-year goals in targeted North...
Reposted 1 month ago
Director, Clinical Systems & Data Management
$205K - $229K *
Lead the charge in enhancing clinical data systems and technology, ensuring reliable, scalable solutions while driving effective collaboration across teams to transform clinical workflows and deliver...
1 month ago
Environmental Consulting Project Director
$202K - $289K *
Champion growth in environmental services by leading business development, managing complex projects, and fostering client relationships in the power industry. Leverage your expertise to navigate regu...
2 days ago
Senior Manager, People Operations
$133K - $183K *
Join a team that's redefining People Operations by leading global strategies and scalable programs. Drive employee lifecycle enhancements, optimize service delivery, and foster a high-performing cultu...
1 week ago
Manager, Strategic Initiatives & Operations - US
$120K - $145K *
Lead transformative initiatives across multiple business functions to drive strategic alignment and operational excellence, optimizing processes and technologies to achieve organizational goals and en...
3 weeks ago
Sr Architect, Professional Services
$160K - $200K *
Empower clients by leading the implementation of innovative solutions, ensuring successful adoption and integration of Omnissa Workspace ONE. Collaborate with diverse teams to drive business outcomes...
1 week ago
$150K - $180K *
Lead a talented design team to shape the user experience across multiple platforms. Define interaction patterns, elevate design standards, and collaborate with cross-functional teams to deliver innova...
2 weeks ago
Senior Manager, Cloud Engineering Governance - FedRAMP
$130K - $160K *
Lead governance initiatives in a multi-cloud environment, managing a team to secure and optimize cloud operations. Oversee compliance, develop policies, and optimize costs while ensuring alignment wit...
Reposted 3 weeks ago
Product Manager, Clinical Programs & Case Management
$86K - $138K *
Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...
5 days ago
Sales Director, Data Solutions
$150K - $180K *
Champion the development of a high-growth data solutions business, driving revenue, client engagement, and team leadership, while shaping product direction in a dynamic, fast-paced environment focused...
Reposted 1 month ago
Enterprise Account Director, New Business
$135K *
Unlock potential by closing enterprise deals that transform early conversations into long-term partnerships. Leverage your expertise in building relationships across key stakeholders to drive signific...
4 weeks ago
Director - Product Management, LATAM
$163K - $297K *
Join a dynamic team to shape the future of digital consumer experiences in LATAM. Lead product strategy and execution for innovative e-commerce solutions, driving customer satisfaction and loyalty whi...
2 days ago
$110K - $130K *
Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...
Reposted 4 days ago
Purchasing - Purchasing Manager
$80K - $95K *
Empower a dynamic team to enhance procurement processes, ensuring timely delivery of materials and services for construction projects while driving operational excellence and collaboration across depa...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.