Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$133K - $166K *

Champion the fundraising efforts of a dynamic corporate finance team, managing complex debt and equity processes while collaborating with senior leadership to craft compelling narratives for investors...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$190K - $275K *

Join a team that's driving strategic technology alliances to transform integrations into robust commercial partnerships, focusing on co-selling, joint marketing, and stakeholder alignment while leadin...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$129K - $162K *

Unlock potential by leading enterprise-wide Cost of Care solutions. Drive scalability, optimize deployment, and enhance operational effectiveness across diverse markets, collaborating with stakeholder...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $190K *

Lead and execute complex commissioning processes in mission-critical environments. Utilize deep technical knowledge to deliver strategic plans and mentor teams while managing multiple projects effecti...

United StatesRemote

Reposted 1 month ago

  •   8 - 10 years exp.  •   Technical Services

$144K - $184K *

Lead the strategy execution for key global clients, driving client value, retention, and new business growth while cultivating trust-based relationships with senior leaders and maximizing account pote...

RemoteRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Business Services

$170K - $190K *

Elevate business systems by leading NetSuite management and integrations. Collaborate with cross-functional teams to ensure scalable, reliable processes while leveraging AI for development. Mentor a t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $100K *

Optimize customer onboarding by managing end-to-end implementations, translating solution designs into actionable configurations, and ensuring seamless project execution while fostering strong client...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $145K *

Join a dynamic team to lead the functional ownership of a critical fraud detection platform. Drive innovation and operational excellence while fostering a culture of accountability and continuous impr...

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$230K - $260K *

Elevate your career by managing complex projects that enhance community resilience. Oversee budgets, coordinate teams, and ensure timely delivery while collaborating with stakeholders to meet project...

2 weeks ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$80K - $95K *

Join a team that's dedicated to managing major capital and expense projects efficiently. Collaborate on developing detailed project plans while ensuring safety and compliance with standards to meet st...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $175K *

Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $125K *

Elevate product strategy and delivery by leading a multidisciplinary team to ensure alignment with stakeholder needs and mission-critical outcomes in a fully remote environment...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $147K *

Oversee project financial performance and analytics, ensuring effective management across complex contracts. Collaborate with teams to enhance processes and deliver actionable insights, driving operat...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to optimizing client business processes through analysis and collaboration. You'll facilitate benchmarking studies, document system customizations, and support solution im...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Grow your career with a strategic leadership role driving product vision, innovation, and profitability. Collaborate across teams to enhance product lifecycle management and market strategies, ensurin...

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$88K - $105K *

Lead the charge in managing cross-functional product development projects, ensuring timely execution and budget adherence while coordinating global teams and stakeholders throughout the entire product...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$70K - $95K *

Deliver impactful project management for complex implementations, leading teams to ensure successful outcomes while cultivating valued client relationships and driving business success through effecti...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$235K - $265K *

Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading a team in Decision Sciences, driving analytics and insights for marketing success. Collaborate with stakeholders to deliver high-quality performance measurement and data-dr...

Yesterday

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Transform the employee experience by leading impactful HR initiatives, managing events, and enhancing organizational culture. Collaborate across teams to drive engagement, support leadership developme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $116K *

Join a dynamic team to develop operational strategies and lead a branch, enhancing customer satisfaction and driving sales growth while training to manage diverse teams and projects effectively...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $105K *

Lead the charge in construction materials testing projects from start to finish, ensuring technical quality, client satisfaction, and financial health while mentoring staff and expanding client relati...

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$140K - $150K *

Reimagine data management as a Senior Technical Product Owner, leading cross-functional teams to drive product vision and execution. Oversee complex SQL Server systems and cloud-native applications, e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.