Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$170K - $185K *

Join a team that's redefining tactical communications and networking strategies for unmanned systems. Leverage your expertise to shape connectivity solutions, ensuring seamless data exchange across jo...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$110K - $130K *

Elevate quality standards by leading the Quality Management System, ensuring compliance with FAA regulations and driving continuous improvement across engineering, manufacturing, and certification act...

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $150K *

Champion the delivery of complex data center construction projects, leading diverse teams and stakeholders to ensure successful outcomes from planning through completion while fostering strong client...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$107K - $300K *

Lead the charge in developing high-performing software engineering teams, designing robust systems, and driving innovation while optimizing processes and enhancing application quality through data-dri...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Innovate and lead product strategy for a cutting-edge SaaS platform, guiding cross-functional teams to deliver exceptional solutions that meet customer needs and drive market success. Collaborate clos...

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $100K *

Champion a safety-first culture by providing expert HSE guidance, ensuring compliance, and driving continuous improvement through systematic inspections and training in a dynamic manufacturing environ...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Unlock potential by leading operations across multiple locations, driving profitability, and fostering a high-performing team. This hands-on role requires strategic oversight, customer service excelle...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Empower consumer experiences by leading product strategy and execution for innovative genomics solutions. Collaborate with cross-functional teams to enhance user satisfaction and drive adoption throug...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$161K - $190K *

Transform the digital commerce experience by owning a high-velocity experimentation roadmap. Collaborate across teams to enhance customer journeys, improve conversion rates, and establish a robust exp...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $195K *

Elevate client relationships by managing key accounts, driving satisfaction and growth. Collaborate with internal teams to deliver tailored solutions, ensuring long-term success and measurable ROI for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Transform data operations by architecting scalable solutions that enhance fan engagement and analytics. Collaborate across teams to integrate systems, ensure data integrity, and drive AI initiatives...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$120K - $150K *

Take ownership of an AI-driven product, shaping strategy, roadmap, and execution for enterprise content insights. Collaborate with cross-functional teams to enhance adoption and value in regulated sec...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engineer innovative data products that empower global businesses. Lead cross-functional teams to define product strategy, manage lifecycles, and drive performance metrics, ensuring alignment with mark...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$151K - $281K *

Lead and develop a team of engineers in the design and validation of sterile drug manufacturing processes, ensuring compliance and quality for successful startup and regulatory approval at a cutting-e...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in managing client and media partner relationships, ensuring exceptional service and effective contract management while driving growth and collaboration in news media investments...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Lead the charge in delivering exceptional service and support to customers, managing maintenance operations, and executing technical strategies while fostering talent development and ensuring high-qua...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$108K - $162K *

Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$130K - $219K *

Engage with customers to identify key challenges and drive product innovation. Collaborate across hardware, software, and AI teams to deliver impactful solutions that enhance physical operations and g...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$180K - $210K *

Shape the future of oncology partnerships by driving strategy and execution to expand Daymark's network among leading practices focusing on value-based care. Cultivate relationships, close deals, and...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Oversee global EPC proposal processes for Battery Energy Storage Systems, collaborating with cross-functional teams to deliver innovative, customer-centric solutions while driving continuous improveme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $145K *

Drive project success as a Global Lead Project Manager, overseeing cross-functional teams to ensure timely, quality delivery of clinical trials while managing customer expectations and financial stewa...

North Carolina, USRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Drive impactful projects in public health by leading teams, managing RFPs, and ensuring client satisfaction through effective collaboration and clear communication...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Enterprise Technology

$130K - $190K *

Shape product strategy and growth for MVCA portfolio, leading innovative initiatives and cross-functional collaboration while managing key product lifecycle stages and enhancing customer engagement...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive operational excellence by leading engineering, data, and AI teams. Collaborate with stakeholders to translate strategic goals into actionable plans, ensuring high-quality project delivery and te...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.