Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$151K - $281K *

Lead and develop a team of engineers in the design and validation of sterile drug manufacturing processes, ensuring compliance and quality for successful startup and regulatory approval at a cutting-e...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Lead the charge in managing client and media partner relationships, ensuring exceptional service and effective contract management while driving growth and collaboration in news media investments...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$110K - $130K *

Lead the charge in delivering exceptional service and support to customers, managing maintenance operations, and executing technical strategies while fostering talent development and ensuring high-qua...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$108K - $162K *

Join a team that's dedicated to enhancing biomedical service operations. Lead a skilled team of technicians, ensuring high-quality support and customer satisfaction across the Pacific Northwest while...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$130K - $219K *

Engage with customers to identify key challenges and drive product innovation. Collaborate across hardware, software, and AI teams to deliver impactful solutions that enhance physical operations and g...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$120K - $145K *

Oversee global EPC proposal processes for Battery Energy Storage Systems, collaborating with cross-functional teams to deliver innovative, customer-centric solutions while driving continuous improveme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$120K - $145K *

Drive project success as a Global Lead Project Manager, overseeing cross-functional teams to ensure timely, quality delivery of clinical trials while managing customer expectations and financial stewa...

North Carolina, USRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$130K - $190K *

Shape product strategy and growth for MVCA portfolio, leading innovative initiatives and cross-functional collaboration while managing key product lifecycle stages and enhancing customer engagement...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Drive operational excellence by leading engineering, data, and AI teams. Collaborate with stakeholders to translate strategic goals into actionable plans, ensuring high-quality project delivery and te...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Drive integrated, compliant media strategies for pharmaceutical brands, leading channel planning, investment decisions, and client engagement to achieve impactful business outcomes throughout launch a...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$60K - $103K *

Help us drive customer satisfaction by resolving warranty cases and nonconformance issues. Collaborate across departments to ensure timely solutions for medium voltage power distribution equipment, en...

3 days ago

  •   Less than 5 years exp.  •   Business Services

$123K - $207K *

Champion the design and ownership of a robust People Data Access & Governance framework, ensuring responsible data access while partnering with cross-functional teams to navigate compliance and ethica...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$128K - $178K *

Lead the evolution of our CMS and AI web strategy, driving product vision and execution for public sector clients. Collaborate with cross-functional teams to deliver innovative, customer-focused solut...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$151K - $178K *

Shape the future of credit decisioning by leading a team focused on automating underwriting processes, enhancing portfolio analytics, and driving policy governance in a fast-paced fintech environment...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$156K - $198K *

Lead the charge in enhancing workplace safety through effective management of EHS programs, audit inspections, and training initiatives, while collaborating closely with supervisors and stakeholders t...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$85K - $100K *

Champion successful project execution by leading cross-functional teams, maintaining schedules, and ensuring adherence to key milestones. Drive financial and operational performance for exceptional cu...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Join a forward-thinking team to define and execute design strategy for AI-driven risk management tools, guiding designers and partners to deliver exceptional user experiences that prioritize risk unde...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $130K *

Join a dynamic team to lead fall protection projects, ensuring timely delivery and fostering strong client relationships while mentoring engineers and managing budgets from design to installation...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$180K - $230K *

Grow your career with a leadership role overseeing global operations, focusing on strategy development, performance management, and cross-department collaboration to drive operational excellence and i...

RemoteRemote

Reposted 5 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive IT quality and compliance initiatives, managing audits and ensuring adherence to regulatory standards. Collaborate with global teams to enhance operational performance and support career develop...

Durham, NCRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Lead the execution and management of IT Quality and Compliance initiatives, ensuring adherence to regulatory standards while guiding team development and fostering collaboration across IT and business...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$178K - $294K *

Join a team that's redefining data engineering and analytics. Lead strategy, architecture, and execution of scalable data solutions while mentoring professionals and driving business outcomes through...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's shaping the future of linear technology by driving product strategy, optimizing market share, and enhancing customer solutions. Leverage your expertise to lead product development a...

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.