Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$80K - $95K *
Lead project coordination efforts by ensuring effective communication and management of materials, schedules, and documentation. Collaborate with teams to streamline processes and enhance project effi...
1 week ago
Traveling Project Manager – Mission Critical
$125K - $200K *
Champion large-scale, complex data center projects from preconstruction to closeout, ensuring budget, schedule, quality, and safety while navigating fast-paced environments and collaborating with dive...
4 weeks ago
Construction Materials Senior Project Manager
$95K - $115K *
Join a dynamic team to oversee construction materials testing projects, manage budgets, ensure quality, and foster client relationships while mentoring junior staff and driving project success...
4 weeks ago
Construction Materials Senior Project Manager
$95K - $115K *
Lead transformative construction materials testing projects, ensuring technical quality, client satisfaction, and financial success. Mentor teams and develop client relationships from initiation throu...
4 weeks ago
Director, HR Business Partner - Product and Engineering
$150K - $215K *
Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...
1 week ago
$105K - $176K *
Lead the charge in tax compliance and provision management, overseeing federal, state, and local returns. Collaborate cross-functionally to ensure timely filings and support tax strategies for busines...
3 weeks ago
$150K - $180K *
Lead the charge in transforming partner data operations and integrations, ensuring efficient case resolution and proactive partner enablement. Drive automation, establish standards, and foster a produ...
1 week ago
Principal Design Program Manager, International Packaging
$120K - $145K *
Lead the charge in shaping global healthcare packaging design. As a Principal Design Program Manager, you'll establish frameworks and standards, drive strategic decisions, and ensure seamless collabor...
2 weeks ago
$95K - $115K *
Champion the successful delivery of projects and technology initiatives by coordinating cross-functional teams and managing risks, ensuring timely and high-quality outcomes that align with business ob...
2 weeks ago
$140K - $190K *
Take ownership of defining and operationalizing a customer ROI framework across teams, fostering strategic growth initiatives through measurable value outcomes while enabling effective customer engage...
Reposted 1 month ago
Senior Manager, Product Management – Field Intelligence
$130K - $155K *
Unlock your potential as a Senior Manager in Product Management, leading the technology strategy and roadmap for a unified Field Intelligence platform. Drive innovation and enhance decision-making thr...
Yesterday
Associate Director - Life Sciences Construction
$165K - $190K *
Lead the charge in delivering strategic cost management services for a major bio-pharmaceutical project, ensuring effective stakeholder engagement and operational excellence throughout the project lif...
1 week ago
Program Manager - Hub Operations
$90K - $110K *
Contribute to the success of pharmaceutical programs by managing client relationships, overseeing daily operations, and driving performance. Collaborate cross-functionally to ensure program execution...
Reposted 3 weeks ago
Global Project Manager (FSP), Remote based in the US
$110K - $130K *
Drive impactful global clinical trials as a Project Manager, leading cross-functional teams to ensure project delivery on time, within budget, and to quality standards while managing vendor relationsh...
2 weeks ago
Project Manager, OSP Construction & Engineering
$77K - $126K *
Take ownership of managing construction projects, ensuring timely, on-budget delivery while collaborating with vendors and adhering to guidelines. Drive process improvements and maintain comprehensive...
3 days ago
Group Manager - Land Development
$110K - $130K *
Transform the landscape of engineering projects by leading complex land development initiatives. Collaborate with clients and teams to drive success, enhance processes, and elevate the company's marke...
2 weeks ago
Senior Manager, Transaction Advisory
$500K+*
Lead the execution of carbon transaction advisory across LAC countries, managing senior government relationships and developing commercialization strategies to support forest protection initiatives an...
Yesterday
Senior Manager, Software Engineering
$180K - $240K *
Empower teams to innovate in residential construction software by leading high-performing engineering groups, fostering Agile practices, and enhancing project management for builders and homeowners al...
2 weeks ago
Program Manager - Healthcare Transformation
$140K - $165K *
Lead the charge in managing strategic healthcare programs, enhancing integrated delivery systems through innovative project solutions and stakeholder engagement while mentoring junior analysts and ove...
1 month ago
Senior Director I, Umbrella Product Management
$160K - $190K *
Join a team that's redefining the Umbrella line of business by overseeing P&L, driving innovative strategies, and collaborating across departments to achieve profitable growth and enhance customer sat...
5 days ago
$95K - $115K *
Join a team that's dedicated to enhancing community living through effective facilities management. Lead maintenance operations, foster strong vendor relationships, and ensure a superior resident expe...
Reposted 1 week ago
Senior Manager, Clinical Operations
$136K - $171K *
Pioneer clinical trial excellence by leading operational planning and execution. Collaborate cross-functionally to ensure compliance, quality, and timely delivery of clinical studies while mentoring j...
4 days ago
Senior Manager, Global Deal Desk
$125K - $150K *
Champion scalable deal operations by leading the Global Deal Desk, optimizing complex agreements across sales, finance, and legal. Drive AI integration to enhance workflows and ensure compliance while...
1 week ago
$80K - $95K *
Accelerate project success by leading A&E initiatives in the telecom sector. Oversee design, coordination, and execution while managing schedules and resources. Collaborate with clients and teams to e...
1 week ago
Senior Project Manager - Transportation Design-Build (PE)
$110K - $130K *
Unlock potential by leading complex transportation design-build projects. Collaborate with multidisciplinary teams and stakeholders to ensure successful project delivery while fostering growth in our...
2 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.