Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$105K - $135K *

Transform product vision into reality by driving execution and collaboration across teams. Leverage data and AI to enhance risk data accessibility, ensuring customers can act swiftly and confidently o...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$174K - $204K *

Drive transformative growth by leading strategic initiatives that redefine operational models and enhance market performance across franchise systems. Collaborate with cross-functional teams to ensure...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Food & Beverages

$137K - $220K *

Lead the charge in managing strategic customer relationships, driving revenue growth, and ensuring account health. Collaborate across teams to deliver innovative hydrogen solutions while navigating co...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Lead multidisciplinary engineering projects, manage branch operations, and foster team growth while ensuring quality and safety standards. Drive business development and mentoring to advance your care...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Lead the charge in driving strategic sales initiatives, managing key accounts, and fostering long-term partnerships. Collaborate with cross-functional teams to identify growth opportunities and delive...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$160K - $200K *

Shape the future of product strategy by leading a high-performing team, driving innovation, and ensuring alignment across operations and technology to deliver exceptional customer value and measurable...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$115K - $140K *

Engage as an experienced implementation leader managing complex client onboarding and execution of digital banking solutions. Collaborate across teams to drive project success, enhance operational eff...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$181K - $245K *

Elevate your career by leading lifecycle marketing strategies that enhance customer engagement, retention, and monetization. Drive impactful programs while managing a high-performing team and collabor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Advance enterprise innovation by leading a collaborative strategy that transforms insights into measurable growth, fostering cross-segment collaboration and foresight to drive long-term opportunities...

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Launch impactful B2B events by developing strategies, managing budgets, and executing flawless experiences. Collaborate with marketing leaders to enhance brand presence and foster relationships throug...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$145K - $175K *

Unlock potential by serving as a strategic advisor to enterprise clients, guiding them through complex stakeholder environments with predictive intelligence and data-driven insights to drive impactful...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Media

$110K - $130K *

Lead the charge in transforming complex genomic data into compelling narratives that resonate with audiences, driving engagement across diverse channels while collaborating with cross-functional teams...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$177K - $221K *

Lead the development and execution of global CMC regulatory strategies to support clinical trials and market applications, ensuring compliance with regulatory requirements throughout the product lifec...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform the internal IT landscape by managing employee support, systems administration, and infrastructure scalability. Drive automation and security initiatives while enhancing user experience in a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$105K - $145K *

Collaborate with cross-functional teams to design integrated solutions that enhance user experience, leveraging AI tools and a design system to create cohesive workflows and drive product value in a B...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$190K - $237K *

Optimize sourcing strategies and procurement processes for clinical operations, ensuring effective vendor management and governance across global clinical trials. Collaborate with cross-functional tea...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Innovate product management across a diverse SaaS portfolio, leading teams to enhance strategy and execution. Collaborate with executives to drive growth and operational excellence in global markets...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Drive pricing strategy and analytics for power distribution products, ensuring competitive market positioning and margin protection. Collaborate cross-functionally to enhance quoting processes and del...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$220K - $340K *

Champion construction delivery excellence across global data center sites, managing GC performance and budgets of $25M+. Lead strategy, negotiate contracts, and represent construction risks to executi...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$168K - $285K *

Shape the future of financial strategy by leading R&D finance, partnering with executives to drive investment decisions, optimize spending, and enhance forecasting accuracy in a dynamic, AI-driven env...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $150K *

Lead the charge in product innovation by managing the full lifecycle from ideation to launch. Collaborate with cross-functional teams to align technical and business goals, ensuring successful product...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$96K - $144K *

Take ownership of contract management by drafting, negotiating, and administering agreements with key customers. Collaborate with cross-functional teams to ensure compliance and operational efficiency...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Business Services

$184K - $200K *

Unlock potential by driving the vision and strategy for innovative products that empower independent candidates and enhance user engagement. Collaborate with cross-functional teams to create scalable...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Business Services

$160K - $187K *

Grow your career with a hands-on Engineering Manager role leading a dynamic team to enhance an AI-powered healthcare hiring platform, ensuring quality, reliability, and innovation across multiple tech...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$190K - $210K *

Lead the charge in strategic AI initiatives, coordinating cross-functional teams to drive program success. Utilize your program management expertise to align priorities, manage risks, and enhance AI c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.