Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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$207K - $311K *

Shape the future of our global GTM strategy by leading capacity planning, territory design, and incentive structures, driving growth and operational excellence across Sales and Customer Success framew...

RemoteRemote

4 weeks ago

  •   8 - 10 years exp.  •   Legal & Accounting

$183K - $305K *

Drive strategic program management in drug development, leading cross-functional teams to achieve goals, budgets, and timelines. Mentor junior staff and influence senior leadership while ensuring effi...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Advance global clinical trials by leading cross-functional teams, ensuring compliance and operational excellence while managing timelines and budgets to deliver impactful results in Oncology research...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$225K - $265K *

Partner with us to lead a high-performing engineering team, driving innovation and efficiency in our travel marketplace. You'll manage project lifecycles, enhance collaboration, and champion a custome...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$114K - $187K *

Champion clinical laboratory operations by managing complex projects, ensuring timely study starts, and collaborating with cross-functional teams to deliver impactful results in precision medicine...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Elevate your career by leading cross-functional teams in drug development. Drive strategic planning, manage risks, and mentor junior colleagues while influencing outcomes in a dynamic environment. Mak...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Transform your career by leading cross-functional teams in drug development. Drive strategic planning, manage risks, and mentor talent while ensuring efficient project execution from preclinical stage...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$183K - $305K *

Join a team that's driving innovation in drug development by leading cross-functional teams, managing strategic plans, and mentoring talent to ensure successful project execution from preclinical stag...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Drive the planning and execution of complex therapeutic programs from discovery to clinic. Serve as a senior program management partner, ensuring successful execution and alignment across cross-functi...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Lead global field operations, driving strategy and execution across sales, technical services, and partner functions. Collaborate with senior leadership to optimize pipeline management, forecasting, a...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Contribute to the enhancement of knowledge products by managing tools, curating content, and ensuring seamless information flow. Collaborate with teams and clients to drive product development and sup...

Yesterday

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$185K - $344K *

Join a dynamic team driving strategic planning and performance management across analytics capabilities. Lead portfolio governance and execution initiatives to align resources and priorities, ensuring...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the optimization of cross-pillar workflows, ensuring technical soundness and operational effectiveness. Collaborate with engineering and product teams to enhance product adoption and drive measur...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Advance your career by coordinating healthcare technology integration across multiple VA sites. Leverage your project management skills to support the Federal Electronic Health Record Modernization pr...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$128K - $178K *

Lead the charge in shaping the future of destination marketing through data-driven insights and innovative product strategies. Collaborate with cross-functional teams to enhance customer experiences a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$123K - $218K *

Champion user-centered information experiences by leading a distributed team to create impactful technical documentation and content strategies that enhance customer and developer engagement across mu...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate your career by managing complex e-discovery projects, mentoring teams, and collaborating with legal professionals to ensure successful outcomes. Drive project execution while fostering strong...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$216K - $236K *

Join a team that's redefining AI product management by driving ROI through innovative solutions. Lead the development of AI capabilities that enhance Alteryx workflows, ensuring faster, better, and ch...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$160K - $195K *

Drive operational excellence and lead a high-performing team to deliver complex digital products. Collaborate with cross-functional teams to define strategies, manage resources, and ensure profitable...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$102K - $154K *

Lead the charge in managing complex customer escalations, driving rapid resolutions and systemic improvements. Collaborate cross-functionally to enhance workflows and customer experiences while ensuri...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$200K - $220K *

Lead product management for an innovative infrastructure automation platform, driving strategy and vision while managing a team of senior product managers. Collaborate cross-functionally to enhance cu...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$122K - $184K *

Lead the implementation of Workday solutions in Higher Education, managing project lifecycles, fostering client relationships, and delivering results while ensuring adherence to budget and timelines...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$160K - $200K *

Join a team that's redefining forensics and collections globally. Lead a skilled team, enhance operational efficiency, and drive client engagement while ensuring compliance and defensibility across re...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Legal & Accounting

$90K - $100K *

Manage multiple digital programs, ensuring exceptional delivery and operational efficiency. Collaborate with client services and channel teams to achieve goals while thriving in a fast-paced environme...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.