Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$120K - $150K *

Transform the supply chain landscape by leading procurement and subcontracting efforts, ensuring compliance with federal regulations while driving efficiency and innovation in support of critical defe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$150K - $165K *

Unlock potential by leading product strategy and lifecycle management in diagnostics. Drive profitability and market performance through cross-functional collaboration, leveraging AI for enhanced deci...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $165K *

Transform product strategy and lifecycle management by leveraging AI insights to enhance portfolio performance, drive profitability, and ensure successful product launches while collaborating across s...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$149K - $224K *

Lead the charge in transforming healthcare solutions by overseeing the entire implementation lifecycle, ensuring quality standards, and driving customer adoption through effective education and suppor...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$108K - $180K *

Join us in leading product strategy and execution for a diverse portfolio, enhancing Provider Contracting and Credentialing. Collaborate with cross-functional teams to drive innovation, improve custom...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Shape the future of client relations as a Program Manager, overseeing program execution, financial oversight, and stakeholder collaboration to drive operational excellence and innovative solutions whi...

North Carolina, USRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$86K - $138K *

Lead the strategy and execution of enterprise data exchange products, ensuring secure and standardized data sharing. Collaborate with stakeholders to drive interoperability and maximize business value...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Advance the administration of Defined Benefit and Retiree Medical plans, ensuring accurate valuations, benefit calculations, and compliance with regulations. Collaborate on special projects while leve...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$120K - $193K *

Join a team that's redefining security product management by leading the strategy and delivery of innovative security solutions. Drive efficiency and compliance while enhancing developer experiences t...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$125K - $135K *

Lead the strategic planning and execution of complex programs across multiple teams, ensuring alignment with business priorities and effective risk management. Drive delivery improvements and maintain...

United StatesRemote

Reposted 5 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $150K *

Engage with policymakers and business leaders to drive revenue opportunities. Shape go-to-market strategies and government affairs initiatives, connecting teams to leverage policy insights for impactf...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$128K - $254K *

Drive the successful delivery of Phase I-IV clinical trials by leading cross-functional teams, managing project timelines, budgets, and quality standards while fostering strong client relationships an...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$70K - $117K *

Lead the charge in optimizing provider networks and managing strategic projects. Collaborate cross-functionally to ensure timely delivery and enhance partnerships, driving success from initiation to c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$190K - $210K *

Transform the owner activation journey by streamlining processes from agreement to live listing. Drive metrics on activation rates and retention while collaborating with teams to enhance onboarding ef...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$125K - $150K *

Lead the charge in monitoring transactional risk for banking and treasury services, ensuring effective fraud detection and credit risk management across multiple program layers while driving resolutio...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$205K - $380K *

Drive transformative supply chain initiatives, providing strategic leadership and operational oversight to enhance efficiency and best practices across client hospitals. Collaborate with C-suite execu...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Healthcare

$145K - $225K *

Lead the charge in software development, driving innovation and collaboration across teams. Oversee strategic planning and team development to enhance product quality and efficiency, while fostering a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$86K - $138K *

Lead the charge in defining product vision and strategy, aligning stakeholders, and overseeing execution. Collaborate across teams to prioritize clinical data assets, ensuring maximum business value a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $172K *

Champion eDiscovery project management by leading high-visibility initiatives for the DOJ. Collaborate with legal teams to ensure seamless project execution across all EDRM phases, delivering quality...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$222K - $288K *

Advance your career by leading global infrastructure strategy and operations. Drive modernization across cloud, networking, and security while ensuring compliance and scalability for 24/7 clinical and...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team to lead advanced scheduling and project controls for solar and energy storage projects. Utilize your expertise in Primavera P6 to develop, analyze, and maintain integrated schedule...

1 week ago

  •   8 - 10 years exp.  •   Staffing

$160K - $190K *

Empower the design and modernization of enterprise cryptographic architecture, translating security standards into automated, reusable capabilities. Lead initiatives in payment and non-payment encrypt...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$132K - $261K *

Drive enterprise-wide digital employee experience initiatives by leading the design and implementation of secure, scalable workplace technologies that enhance productivity and operational efficiency a...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$175K - $210K *

Drive the vision and strategy for a diverse product portfolio, enhancing market leadership and customer value. Lead cross-functional teams to ensure successful product lifecycle management and alignme...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.