Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$150K - $180K *

Lead a dynamic account management team, driving strategic relationships with major health systems. Foster high-touch engagement, ensuring customer success and operational excellence while directly man...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Lead quality initiatives to ensure compliance and drive continuous improvement across the organization while collaborating with cross-functional teams to enhance product consistency and customer satis...

Reposted today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$192K - $240K *

Unlock your potential as a Product + Design Strategist, leading ambiguous projects from concept to execution. Collaborate with cross-functional teams to create innovative, user-centered experiences an...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$189K - $361K *

Elevate your career by leading a dynamic team to innovate and scale AI solutions that drive enterprise transformation. Shape the future of generative AI and autonomous systems while influencing strate...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$126K - $176K *

Contribute to project success by managing costs, overseeing bids, and fostering strong client relationships. Engage with diverse teams to ensure transparency and effective communication throughout the...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$144K - $288K *

Lead the charge in transforming customer identity platforms, driving modernization and operational excellence while overseeing a multi-team engineering organization to enhance security and customer en...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Advance your career by leading finance transformation initiatives and data governance. Collaborate with cross-functional teams to optimize processes, drive AI adoption, and enhance decision-making acr...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$115K - $173K *

Join a team that's driving infrastructure initiatives by managing projects, budgets, and resources. Collaborate with cross-functional teams to ensure compliance and deliver measurable business value w...

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$350K - $500K+*

Lead and innovate in game production, driving strategic initiatives and excellence across a diverse portfolio. Collaborate with teams to deliver high-quality gaming experiences while fostering a cultu...

RemoteRemote

2 weeks ago

  •   11 - 15 years exp.  •   Hospitality & Recreation

$180K - $210K *

Elevate creative excellence by leading a multidisciplinary team, setting vision and quality standards, and driving impactful brand strategies across diverse channels in a dynamic healthcare environmen...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$119K - $140K *

Tackle strategic product management for a technical product line, engaging stakeholders to define features and ensure delivery of capabilities while driving product performance and improvements across...

Reposted 4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$205K - $240K *

Elevate technology strategy and operations for North America's supply chain, leading engineering teams to optimize platforms and processes. Drive innovation in order management and logistics while ens...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Join a team that's redefining product management by leading cross-product initiatives and shared services. Collaborate with diverse teams to drive innovation, enhance platform capabilities, and delive...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Information Technology

$68K - $122K *

Drive impactful architectural design efforts while leading the production of construction documents. Collaborate on complex projects, mentor junior designers, and ensure quality and compliance across...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$136K - $220K *

Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Join a team that's redefining audit practices by leading the transition to an agentic operating model. Collaborate across functions to innovate audit methodologies and drive transformation for clients...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$126K - $173K *

Shape the future of enterprise decisioning by leading cross-functional product initiatives that enhance customer experiences and drive operational readiness across multiple business channels...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in advancing AI product innovation, transforming concepts into market-ready solutions while collaborating with cross-functional teams to deliver exceptional user experiences...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of partner engagement by leading global programs that enhance value across the customer lifecycle. Collaborate with cross-functional teams to streamline processes, improve partner exp...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Join a team that's dedicated to enhancing client delivery and operational efficiency. As a Program Manager, you'll lead complex projects, manage cross-functional teams, and drive successful software i...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$142K - $213K *

Join us to lead the proposal lifecycle for federal opportunities, collaborating with cross-functional teams to create compelling submissions that enhance win probability and support mission-driven out...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$143K - $273K *

Join a team that's shaping innovative HR strategies to drive business success. As a key advisor to senior leaders, you'll influence talent solutions and foster a culture of growth and agility across t...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$96K - $144K *

Lead the charge in delivering exceptional customer service and technical support at assigned medical equipment sites, ensuring compliance with contracts and fostering strong client relationships throu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$162K - $185K *

Drive strategic product development to meet growth goals, prioritizing user impact and results while collaborating with cross-functional teams to deliver innovative solutions that resonate with both B...

United StatesRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$244K - $305K *

Drive financial strategy and analysis for global commercialization efforts, partnering with cross-functional teams to enhance decision-making and support successful product launches in the biopharmace...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.