Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$90K - $145K *

Join a team that's driving growth through innovative product marketing strategies. You'll shape messaging, lead go-to-market initiatives, and enhance market positioning, ensuring our solutions resonat...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$119K - $186K *

Transform the future of supply chain technology by leading innovation initiatives, managing a structured evaluation process, and engaging stakeholders to drive measurable value and strategic alignment...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$164K - $205K *

Elevate scientific rigor in real-world evidence development. Collaborate with cross-functional teams to ensure agent conceptualization and evaluation meet scientific standards, driving impactful solut...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $170K *

Champion the go-to-market strategy for streaming advertising, leading a product marketing team to craft compelling messaging and drive revenue growth. Collaborate across departments to ensure alignmen...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$204K - $290K *

Manage the Resilience Engineering team to enhance system reliability through production load testing and chaos engineering while fostering a proactive safety culture across engineering practices...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in designing innovative employee benefit plans that enhance workforce engagement and align with strategic goals. Collaborate across teams to ensure competitive, compliant, and cost-eff...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$123K - $169K *

Drive your career with end-to-end management of new product development programs, ensuring alignment across teams and delivering innovative solutions for critical digital infrastructure in a dynamic e...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Innovate inspiring environments by leading project teams, managing client relationships, and ensuring successful project delivery. Leverage technical expertise and collaborative leadership to create t...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$184K - $194K *

Drive your career as a Senior Product Manager, shaping innovative retailer experiences and analytics solutions. Lead cross-functional teams to deliver impactful products that empower retailers to thri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$98K - $122K *

Transform client onboarding processes by leading end-to-end implementations for pharmacy and medical benefits, ensuring project success through meticulous planning and strategic communications...

Reposted 6 days ago

  •   Less than 5 years exp.  •   Healthcare

$168K - $285K *

Shape the future of financial strategy by leading R&D finance, partnering with executives to drive investment decisions, optimize spending, and enhance forecasting accuracy in a dynamic, AI-driven env...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$119K - $190K *

Shape the future of our Corporate Functions by partnering with senior leaders to drive talent strategy, organizational effectiveness, and leadership development. Leverage data and insights to influenc...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$83K - $143K *

Advance the Power Protection & Automation Engineering Development Program by mentoring recent graduates, coordinating training, and enhancing technical skills in a dynamic, supportive environment focu...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$125K - $150K *

Engage in strategic leadership for non-sterile manufacturing operations, ensuring compliance and efficiency in packaging and assembly. Drive continuous improvement and operational excellence in alignm...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$138K - $165K *

Drive the end-to-end lifecycle of innovative AI-powered products, shaping strategy and vision while collaborating cross-functionally to deliver exceptional business and customer value through effectiv...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$103K - $123K *

Drive growth by managing a sales territory, building relationships, and generating premium. Leverage existing partnerships while prospecting new agencies to achieve targets and expand market presence...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $115K *

Transform project delivery by leading teams and managing client relationships. Leverage your expertise in interior design to ensure excellence in execution, while fostering collaboration and innovatio...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$135K - $160K *

Transform OEM partnerships by driving strategic growth and innovative solutions. Leverage market insights and relationship-building skills to negotiate impactful deals and collaborate with senior lead...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$178K - $294K *

Join a team that's redefining data engineering and analytics. Lead strategy, architecture, and execution of scalable data solutions while mentoring professionals and driving business outcomes through...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$125K - $150K *

Bring your expertise to drive revenue growth in healthcare through consultative sales and strategic partnerships. Own the full sales cycle, collaborate cross-functionally, and mentor future hires in a...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$246K - $332K *

Transform the future of field operations by leading strategic initiatives that enhance commercial effectiveness and drive measurable impact across customer-facing teams. Collaborate with cross-functio...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Grow your career with a dynamic role managing high-value projects, ensuring safe, timely, and cost-effective execution. Lead cross-functional teams and interface with clients in diverse industries acr...

Reposted 3 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead the development and execution of change management strategies to drive successful organizational transformation initiatives across multiple construction projects, ensuring stakeholder engagement...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$108K - $184K *

Champion strategic initiatives in Provider Network Operations, overseeing key functions like Provider Relations and Credentialing. Drive performance and compliance across Medicaid, Medicare, and Comme...

North Carolina, USRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$140K - $180K *

Elevate customer insights by translating data into actionable product capabilities. Collaborate with cross-functional teams to prioritize initiatives, enhance marketing performance, and leverage AI fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.