Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Senior Manager, Worldwide SSG Sales Programs
$120K - $145K *
Unlock the potential of global sales initiatives by designing and executing strategic programs that enhance revenue growth and seller productivity across diverse markets. Collaborate with cross-functi...
Yesterday
Executive Director, Technology
$175K - $215K *
Elevate the technology function by leading engineering, delivery, and operations. Collaborate closely with leadership to shape technical strategy, ship code weekly, and ensure high standards in a dyna...
2 weeks ago
$100K - $130K *
Transform healthcare by leading a dynamic PMO, ensuring program transparency and compliance across multiple customer accounts while fostering collaboration and continuous improvement...
Yesterday
Director, Business Operations & Account Management
$125K - $150K *
Shape and elevate business operations and account management, driving resource optimization and client satisfaction. Collaborate with leadership to enhance project delivery and expand client relations...
6 days ago
Executive Director, Manufacturing
$175K - $210K *
Lead operational excellence in biopharmaceutical manufacturing, overseeing GMP processes, technology transfers, and clinical supply. Drive strategic initiatives, manage CDMO relationships, and build a...
Today
$190K - $220K *
Champion innovation and execution as you lead product management across diverse e-commerce channels. Drive strategic roadmaps, manage global teams, and deliver cutting-edge solutions that enhance cust...
3 days ago
Director, Leadership, Culture & Change
$187K - $359K *
Empower organizational success by leading change management and culture integration initiatives. Drive alignment among leadership, enhance employee engagement, and ensure effective communication throu...
3 weeks ago
Sr Architect, Professional Services
$160K - $200K *
Empower clients by leading the implementation of innovative solutions, ensuring successful adoption and integration of Omnissa Workspace ONE. Collaborate with diverse teams to drive business outcomes...
1 week ago
Director, Market Growth Strategy, Molecule to Market (Biologics)
$185K - $256K *
Elevate the market growth strategy for biologics research, driving software adoption and AI use cases. Collaborate with global teams and engage with industry leaders to shape the future of molecular t...
2 weeks ago
$130K - $175K *
Champion the development of access controls within our IAM/IGA system, optimizing policies and ensuring secure, scalable access management across enterprise applications while collaborating with cross...
1 week ago
Director, Software Engineering
$150K - $180K *
Architect and optimize data pipelines and ML models, leading cross-organizational initiatives. Drive technical execution for large-scale programs, ensuring system reliability and performance while gui...
1 week ago
$150K - $180K *
Elevate product innovation by leading the development of an AI-native solution. Define vision, strategy, and roadmap while collaborating with cross-functional teams to transform clinical operations th...
Today
Director, Leadership, Culture & Change
$187K - $359K *
Shape organizational change by leading integration strategies, fostering leadership alignment, and enhancing culture integration. Collaborate with executives to ensure successful adoption of transform...
3 weeks ago
Producer, Senior Vice President
$180K - $220K *
Advance your career by leveraging your networking skills to drive new business, collaborate on strategic plans, and provide innovative risk solutions while managing a diverse portfolio of clients in a...
3 days ago
Senior Program Manager, Contingent Workforce
$107K - $180K *
Drive the strategy and operations of a dynamic contingent workforce program, enhancing governance and service delivery. Collaborate cross-functionally to implement scalable processes and support inter...
Today
Director, Business Strategy and Operations, Global Clinical Development Operations (GCDO)
$192K - $288K *
Join us as a strategic partner in global clinical development operations, driving workforce planning, budget management, and continuous improvement initiatives. Collaborate with leadership to enhance...
Yesterday
Manager, Clinical Data Management
$110K - $130K *
Innovate within a dynamic team, driving impactful projects and solutions that enhance operational efficiency and foster growth across multiple departments. Your expertise will shape strategic initiati...
Yesterday
$116K - $210K *
Help us optimize subcontractor performance by providing strategic oversight and guidance. Collaborate with leadership and teams to ensure alignment with program objectives, while mentoring junior staf...
Yesterday
Salesforce Technical Project Manager
$110K - $130K *
Elevate the delivery of Salesforce programs by leading end-to-end project management, ensuring compliance, and fostering collaboration across teams to enhance federal application modernization efforts...
1 week ago
Technical Project Manager - Identity, Credential, and Access Management (ICAM)
$112K - $179K *
Lead the charge in managing complex IT projects from concept to implementation, ensuring timely delivery and compliance with federal standards. Collaborate with stakeholders to drive project success i...
Today
Director, Franchise Portfolio Management - CNS
$150K - $180K *
Pioneer brand strategy and portfolio management to drive product excellence and optimize revenue. Lead cross-functional teams through lifecycle stages, ensuring strategic alignment and market readines...
Reposted 3 weeks ago
$79K - $87K *
Join a team that's dedicated to enhancing educational equity through strategic program management. As a Senior Program Manager, you'll lead initiatives, coordinate events, and engage with stakeholders...
1 week ago
$194K - $285K *
Innovate in the credit space by leading a dynamic underwriting team. Drive strategy, mentor talent, and establish best-in-class credit programs while collaborating with internal and external partners...
1 week ago
Sr. Director, Strategy & Execution
$160K - $200K *
Transform the future of go-to-market strategy by leading cross-functional teams, driving execution governance, and shaping long-range plans to achieve growth objectives in a dynamic, global environmen...
3 weeks ago
Director of Product, AI Growth
$238K - $357K *
Transform growth strategies by leading AI initiatives, targeting key customers, and driving adoption through innovative partnerships and market insights. Collaborate across teams to enhance product of...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.