Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$110K - $130K *

Transform your career by leading IT operations and team development, enhancing service delivery, and managing technology solutions for a dynamic workforce. Drive improvements and ensure seamless suppo...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$196K - $210K *

Partner with us to shape the future of semiconductor workforce development by aligning industry needs with educational strategies, fostering partnerships, and leading initiatives that ensure technical...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Partner with us to build a scalable sales operations framework across the Americas, enhancing forecast accuracy and pipeline management while fostering strong relationships with field leadership and d...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Consumer Technology

$95K - $158K *

Champion safety initiatives by managing enterprise-wide programs, ensuring compliance, and enhancing data solutions. Collaborate across departments to drive effective training and performance analytic...

1 week ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$200K - $250K *

Drive critical initiatives by navigating ambiguity, building effective operating models, and ensuring measurable outcomes in a dynamic environment. Engage with leadership to implement AI solutions and...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$132K - $199K *

Lead the charge in driving Professional Services sales and client success within the US Public Sector, collaborating across teams to maximize revenue, enhance client relationships, and ensure successf...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $190K *

Accelerate progress at a leading Customer Success team, driving renewal outcomes and enhancing team effectiveness through innovative engagement strategies and AI-driven solutions for a diverse portfol...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $150K *

Lead the charge in defining and executing product strategies for Benefits, collaborating with cross-functional teams to drive innovation and deliver customer value through data-driven insights and aut...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$130K - $160K *

Join a dynamic team to drive integrated marketing strategies that enhance brand visibility and support business growth through innovative campaigns, digital activation, and thought leadership across m...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $185K *

Elevate executive and client experiences by designing luxury hospitality programs across a national portfolio, ensuring exceptional service standards and memorable interactions in corporate environmen...

United StatesRemote

Reposted 6 days ago

  •   8 - 10 years exp.  •   Business Services

$160K - $190K *

Empower your career by partnering with the Science Leadership Team to drive strategic initiatives, enhance operational effectiveness, and translate scientific vision into impactful outcomes across div...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$163K - $297K *

Join a dynamic team to shape the future of digital consumer experiences in LATAM. Lead product strategy and execution for innovative e-commerce solutions, driving customer satisfaction and loyalty whi...

RemoteRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $163K *

Lead and manage client-facing teams to deliver high-quality card processing projects, ensuring successful implementations and client satisfaction through effective project management and strategic ove...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $185K *

Lead global project management efforts, ensuring timely delivery and quality standards while fostering client relationships and team collaboration. Drive operational excellence in clinical research, p...

Durham, NCRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K - $127K *

Lead the charge in delivering impactful Rolling Stock Overhaul Programs, driving performance, maximizing fleet availability, and ensuring project execution to enhance rail transportation effectiveness...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Advance operational excellence by leading large-scale initiatives across multi-site manufacturing. Collaborate effectively with cross-functional teams to achieve strategic goals and drive sustainable...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$154K - $180K *

Unlock your potential as a strategic leader driving customer support excellence. Own high-impact programs, optimize processes, and collaborate with cross-functional teams to enhance customer experienc...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$218K - $256K *

Lead the charge in shaping IT strategy and operations for a remote-first SaaS company. Drive service delivery, enhance employee technology experiences, and build a high-performing IT organization whil...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$178K - $261K *

Lead the charge in shaping a secure and seamless identity experience for millions globally. Drive strategy for authentication, account management, and recovery while collaborating across teams to prot...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$143K - $179K *

Shape and lead client implementations for a cutting-edge trading platform, guiding asset and wealth managers through system configuration and go-live processes while ensuring client satisfaction and p...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Finance & Insurance

$194K - $242K *

Unlock potential by leading product marketing strategies in GLP-1 and cardiometabolic health. Collaborate with cross-functional teams to enhance buyer clarity and sales effectiveness, while coaching a...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Join a team that's advancing oncology solutions by managing global clinical trials. Lead project execution from protocol development to study closeout, ensuring quality and compliance while fostering...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead the charge in executing digital product initiatives for veterinary health. Collaborate across teams to prioritize backlogs, write user stories, and enhance user experiences, ensuring alignment be...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$164K - $246K *

Collaborate with cross-functional teams to translate cloud requirements into actionable product strategies, ensuring technical excellence and successful implementations in complex environments...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Information Technology

$245K - $392K *

Unlock potential by leading finance transformation initiatives that leverage AI, automation, and advanced analytics. Drive a multi-year roadmap, modernize workflows, and shape a high-performing financ...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.