Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$195K - $325K *

Unlock potential by driving AI solutions across diverse business units, identifying high-impact opportunities, and shaping strategic initiatives that enhance insights and decision-making processes glo...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$170K - $185K *

Join a team that's redefining tactical communications and networking strategies for unmanned systems. Leverage your expertise to shape connectivity solutions, ensuring seamless data exchange across jo...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$80K - $145K *

Lead the charge in managing and delivering clinical portfolio initiatives with strong project management skills. Drive collaboration across teams, ensuring alignment to scope, timelines, and governanc...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $145K *

Manage and deliver clinical portfolio initiatives, ensuring project alignment, accountability, and stakeholder coordination while operating independently through all phases of implementation...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Pioneer a data-driven future by leading product strategy for data science solutions. Drive innovation, oversee development, and ensure alignment with business goals to deliver impactful analytics prod...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Drive product innovation by designing AI-enabled workflows that simplify complex insurance operations, ensuring user trust and operational efficiency through close collaboration with engineering and g...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $200K *

Optimize technology risk management across the enterprise by leading proactive assessments, ensuring alignment with regulatory standards, and embedding risk insights into decision-making for cloud, cy...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$157K - $283K *

Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$160K - $175K *

Lead strategic initiatives to enhance customer success for high-value enterprise accounts, fostering long-lasting partnerships, driving engagement, and optimizing retention while managing a high-perfo...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$130K - $155K *

Lead and inspire engineering teams to enhance digital acquisition and onboarding experiences. Collaborate with Product and Design to deliver impactful consumer-facing projects while fostering a cultur...

Yesterday

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $140K *

Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Elevate customer success by leading a high-performing Account Management team. Drive retention and revenue growth through strategic engagement and operational excellence while collaborating cross-func...

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $215K *

Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$168K - $207K *

Drive strategic leadership and operational excellence at the DIU OnRamp Hub, connecting defense innovation with commercial technologies. Engage stakeholders, foster partnerships, and ensure mission al...

6 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$112K - $135K *

Shape the future of product management by driving strategic initiatives, defining vision, and delivering impactful outcomes through collaboration and leadership across diverse teams and stakeholders...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $125K *

Pioneer the implementation of Interactive Response Technology (IRT) in clinical studies. Lead cross-functional teams, manage timelines, and ensure compliance while providing expert guidance and suppor...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$97K - $143K *

Join a team that's driving innovation by leading complex product development projects. You'll collaborate across functions to optimize productivity and ensure business goals are met, all while fosteri...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$97K - $143K *

Advance your career by leading complex, multi-disciplinary projects to drive continuous improvement and optimize productivity across cross-functional teams, ensuring business goals are met and exceede...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $180K *

Unlock potential by managing key relationships with insurance partners, overseeing operations, and ensuring compliance in a dynamic, team-focused environment. Thrive in a collaborative setting that dr...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Champion data-driven decision-making by establishing a unified product metrics framework. Collaborate across teams to enhance product health insights, streamline reporting, and drive strategic initiat...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Join a team that's dedicated to enhancing customer success through expert guidance in Privilege Access Management. Leverage your technical skills to support enterprise clients, ensuring seamless deplo...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$154K - $193K *

Drive AI transformation by building client relationships, leading engagements, and delivering results. Own the sales process from prospecting to execution, ensuring successful integration of AI soluti...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$150K - $180K *

Transform the software development landscape by defining a cohesive end-to-end experience, integrating planning to verification workflows across teams. Lead product strategy and execution, influencing...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.