Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$195K - $325K *
Unlock potential by driving AI solutions across diverse business units, identifying high-impact opportunities, and shaping strategic initiatives that enhance insights and decision-making processes glo...
1 week ago
$90K - $110K *
Join a team that's redefining change management in healthcare. Support the adoption of innovative informatics solutions, ensuring seamless transitions and user readiness across the Veterans Health Adm...
3 weeks ago
Director, Advanced Missions Group - Tactical Communications & Networking
$170K - $185K *
Join a team that's redefining tactical communications and networking strategies for unmanned systems. Leverage your expertise to shape connectivity solutions, ensuring seamless data exchange across jo...
3 weeks ago
Project Manager, Clinical Portfolio
$80K - $145K *
Lead the charge in managing and delivering clinical portfolio initiatives with strong project management skills. Drive collaboration across teams, ensuring alignment to scope, timelines, and governanc...
Reposted 4 weeks ago
Project Manager, Clinical Portfolio
$80K - $145K *
Manage and deliver clinical portfolio initiatives, ensuring project alignment, accountability, and stakeholder coordination while operating independently through all phases of implementation...
Reposted 4 weeks ago
Director of Product Management, Data Science
$150K - $180K *
Pioneer a data-driven future by leading product strategy for data science solutions. Drive innovation, oversee development, and ensure alignment with business goals to deliver impactful analytics prod...
3 weeks ago
$110K - $130K *
Drive product innovation by designing AI-enabled workflows that simplify complex insurance operations, ensuring user trust and operational efficiency through close collaboration with engineering and g...
Reposted 3 weeks ago
Director, Technology Risk Management
$150K - $200K *
Optimize technology risk management across the enterprise by leading proactive assessments, ensuring alignment with regulatory standards, and embedding risk insights into decision-making for cloud, cy...
3 weeks ago
Business Development Director, DOE
$157K - $283K *
Lead the charge in driving business growth by developing strategic partnerships and innovative solutions for federal clients, while collaborating with cross-functional teams to deliver exceptional res...
1 week ago
Senior Manager of Customer Success (Enterprise)
$160K - $175K *
Lead strategic initiatives to enhance customer success for high-value enterprise accounts, fostering long-lasting partnerships, driving engagement, and optimizing retention while managing a high-perfo...
Reposted 4 weeks ago
Senior Manager, Software Engineering
$130K - $155K *
Lead and inspire engineering teams to enhance digital acquisition and onboarding experiences. Collaborate with Product and Design to deliver impactful consumer-facing projects while fostering a cultur...
Yesterday
Director, Client Media Solutions
$100K - $140K *
Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...
6 days ago
$120K - $145K *
Elevate customer success by leading a high-performing Account Management team. Drive retention and revenue growth through strategic engagement and operational excellence while collaborating cross-func...
1 week ago
Director, HR Business Partner - Product and Engineering
$150K - $215K *
Collaborate with senior leaders to design and implement global HR strategies, driving organizational performance and employee engagement while leading a team of HR professionals in a dynamic environme...
1 week ago
Managing Director, Defense Innovation Unit OnRamp Hub
$168K - $207K *
Drive strategic leadership and operational excellence at the DIU OnRamp Hub, connecting defense innovation with commercial technologies. Engage stakeholders, foster partnerships, and ensure mission al...
6 days ago
Lead Product Manager; Testing Lead, WIM Operations, Account Opening & Maintenance
$112K - $135K *
Shape the future of product management by driving strategic initiatives, defining vision, and delivering impactful outcomes through collaboration and leadership across diverse teams and stakeholders...
Yesterday
IRT Project Manager, Remote US
$110K - $125K *
Pioneer the implementation of Interactive Response Technology (IRT) in clinical studies. Lead cross-functional teams, manage timelines, and ensure compliance while providing expert guidance and suppor...
Today
Program Manager I - Product Development
$97K - $143K *
Join a team that's driving innovation by leading complex product development projects. You'll collaborate across functions to optimize productivity and ensure business goals are met, all while fosteri...
Today
Program Manager I - Product Development
$97K - $143K *
Advance your career by leading complex, multi-disciplinary projects to drive continuous improvement and optimize productivity across cross-functional teams, ensuring business goals are met and exceede...
Today
$135K - $180K *
Unlock potential by managing key relationships with insurance partners, overseeing operations, and ensuring compliance in a dynamic, team-focused environment. Thrive in a collaborative setting that dr...
4 weeks ago
Senior Product Management Operations Manager
$120K - $145K *
Champion data-driven decision-making by establishing a unified product metrics framework. Collaborate across teams to enhance product health insights, streamline reporting, and drive strategic initiat...
6 days ago
Senior Technical Account Manager
$110K - $130K *
Join a team that's dedicated to enhancing customer success through expert guidance in Privilege Access Management. Leverage your technical skills to support enterprise clients, ensuring seamless deplo...
3 weeks ago
$120K - $145K *
Unlock potential by leading strategic partnerships and driving growth initiatives. Collaborate cross-functionally to enhance business opportunities and ensure partner success through data-driven insig...
Today
Principal, AI Transformation Lead
$154K - $193K *
Drive AI transformation by building client relationships, leading engagements, and delivering results. Own the sales process from prospecting to execution, ensuring successful integration of AI soluti...
Reposted 2 weeks ago
Principal Product Manager, AI Software Factory
$150K - $180K *
Transform the software development landscape by defining a cohesive end-to-end experience, integrating planning to verification workflows across teams. Lead product strategy and execution, influencing...
Reposted 3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.