Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$146K - $234K *

Innovate comprehensive security strategies for a large-scale cloud ecosystem, ensuring compliance and risk mitigation while leading cross-functional teams to protect organizational assets and enhance...

United StatesRemote

Yesterday

  •   15+ years exp.  •   Aerospace & Defense

$204K - $290K *

Create a groundbreaking consumer loyalty program that enhances user engagement and retention. Drive the vision, launch rewards, and collaborate across teams to ensure a seamless experience that positi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Champion the end-to-end management of complex healthcare programs, ensuring operational readiness and compliance. Collaborate with teams and clients to drive successful implementations while maintaini...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead complex healthcare project initiatives, ensuring successful implementation and operational readiness while maintaining high standards of governance. Foster strong partnerships with clients, manag...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate client outcomes by managing complex AI and data programs. Serve as the primary contact for multi-geo teams, ensuring technical delivery aligns with business goals. Foster strong relationships...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$155K - $410K *

Deliver strategic oversight as a PMO Director, guiding project portfolios, enhancing client relationships, and mentoring leaders while driving program success across multiple initiatives and aligning...

6 days ago

  •   8 - 10 years exp.  •   Legal & Accounting

$105K - $176K *

Lead the charge in tax compliance and provision management, overseeing federal, state, and local returns. Collaborate cross-functionally to ensure timely filings and support tax strategies for busines...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$80K - $95K *

Help us manage diverse projects that drive strategic growth and collaboration across teams. As a key member of the EPMO, you'll ensure project success through effective stakeholder management and cont...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Partner with us to transform customer experience operations into a seamless, data-driven journey. Your leadership will unify departments for consistency, enabling effective strategies that enhance cus...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $114K *

Lead the charge in optimizing production efficiency and safety in a dynamic manufacturing environment. Drive continuous improvement initiatives while ensuring quality standards and financial goals are...

2 days ago

  •   5 - 7 years exp.  •   Food & Beverages

$236K - $354K *

Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage the full project lifecycle, ensuring timely delivery and quality standards. Lead cross-functional teams across U.S. and China, driving accountability and continuous improvement in project execu...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Manage multiple Corporate Performance Management projects, providing strategic guidance and ensuring timely deliverables. Utilize strong communication and organizational skills to coordinate tasks and...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $95K *

Manage diverse construction projects by leading teams, ensuring client satisfaction, and navigating budgets, schedules, and risks. Collaborate with stakeholders to deliver exceptional results while fo...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $105K *

Optimize project delivery by leading diverse construction initiatives, managing budgets, schedules, and risks while ensuring exceptional client service and collaboration across teams in a dynamic envi...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$80K - $95K *

Transform your career by leading diverse construction projects, managing budgets, schedules, and risks while ensuring exceptional client service. Collaborate with teams to drive project success and en...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Join a team that's dedicated to enhancing patient access through strategic design and management of support programs. Oversee vendor relationships and ensure compliance while driving initiatives that...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Join a team that's driving strategic partnerships in Retail and Hospitality. Manage relationships with technology providers, identify growth opportunities, and develop compelling business cases to enh...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$111K - $145K *

Lead transformative IT projects from inception to completion, ensuring timely delivery and budget adherence. Collaborate across departments to translate business needs into actionable plans while mana...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in managing complex ITS and traffic management projects, overseeing planning, design, and deployment. Collaborate with multidisciplinary teams to enhance transportation systems and imp...

2 days ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$171K - $338K *

Lead the charge in transforming HR and IT service delivery through innovative ServiceNow HRSD solutions, managing client relationships, and driving program success across multiple workstreams in a dyn...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$171K - $338K *

Lead the charge in transforming HR and IT service delivery through innovative ServiceNow HRSD solutions, managing client relationships, and driving program success across multiple workstreams in a dyn...

1 week ago

  •   8 - 10 years exp.  •   Business Services

$125K *

Lead the vision and strategy for a transformative platform, driving AI-first solutions that enhance data intelligence in legal tech. Collaborate cross-functionally to shape product architecture and de...

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Elevate product strategy and execution by leading cross-functional teams to deliver innovative solutions that enhance legal professionals' workflows, driving revenue growth and competitive advantage i...

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $189K *

Elevate organizational efficiency by leading Workday Absence and Time Tracking solutions. Collaborate cross-functionally to optimize processes, ensuring compliance and enhancing user experience as the...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.