Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Director, Program Management Jobs in North Carolina

Sort By: Relevance

$110K - $120K *

Elevate talent management by executing core programs, enhancing employee experience, and driving performance initiatives. Lead cross-functional projects, ensuring accountability and operational contin...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $120K *

Unlock the potential of Talent Management by leading performance cycles, enhancing employee relations, and driving strategic initiatives. This hands-on role requires expertise in HR operations, projec...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $169K *

Lead the charge in enhancing customer success initiatives by driving engagement, optimizing processes, and fostering strong relationships. Collaborate with cross-functional teams to ensure exceptional...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in developing our ELERA channel strategy. Collaborate with partners to drive revenue, build enablement programs, and expand our market reach while ensuring success through effective ex...

1 month ago

  •   11 - 15 years exp.  •   Information Technology

$76K - $115K *

Join a team that's shaping the future of customer education through innovative instructional design. Leverage your expertise to create engaging learning experiences that empower users and drive succes...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$172K - $269K *

Lead and modernize global security operations, managing a distributed team while enhancing detection strategies and incident response. Drive AI integration for efficiency and ensure accountability thr...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$130K - $163K *

Shape the future of AI in our organization as a strategic leader driving enterprise-wide adoption and integration of AI technologies, enhancing productivity and delivering measurable results through i...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$112K - $120K *

Optimize client success by leading end-to-end implementations for banks and credit unions, ensuring timely launches and measurable value through strategic guidance and cross-functional collaboration...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$165K - $175K *

Unlock potential by leading enterprise data engineering initiatives, driving platform modernization, and enhancing operational excellence. Collaborate with cross-functional teams to deliver scalable...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Champion project success by managing client engagements from kickoff to completion. Collaborate across teams to ensure timely delivery, effective communication, and alignment with client expectations...

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$161K - $190K *

Transform the digital commerce experience by owning a high-velocity experimentation roadmap. Collaborate across teams to enhance customer journeys, improve conversion rates, and establish a robust exp...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$130K - $150K *

Unlock potential by leading the People Technology & Operations team, optimizing systems like Workday, and driving automation and AI solutions to enhance the employee experience and streamline operatio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$217K - $298K *

Lead the charge in shaping Root's platform and AI engineering strategy, overseeing critical infrastructure and driving operational excellence across teams to deliver intelligent products at scale...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $150K *

Empower organizational excellence by leading strategic initiatives in process optimization and continuous improvement across cross-functional teams, ensuring alignment with business goals and enhancin...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$185K - $344K *

Join a team that's redefining market access through innovative data partnerships. Lead strategic collaborations, ensure data compliance, and drive insights that enhance decision-making and patient ser...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform client relationships by driving sales growth and delivering innovative medtech solutions. Collaborate with cross-functional teams to assess needs, develop strategies, and enhance brand value...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Transform customer experiences by leading global service delivery initiatives, managing executive engagements, and overseeing vendor relationships. Drive strategic programs that enhance operational ex...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$145K - $288K *

Shape the future of finance by leading transformation initiatives, modernizing technology stacks, and integrating AI to enhance operational efficiency across multiple finance domains with measurable b...

Durham, NCRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Shape the future of donation practices by leading strategic initiatives and teams dedicated to enhancing donor family experiences and ensuring compassionate, informed decision-making throughout the do...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $270K *

Elevate your career by leading global executive recruiting efforts, shaping talent strategies, and building high-performing teams. Drive impactful searches and foster relationships with senior leaders...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$165K - $200K *

Transform your career by leading product management for data services, driving innovation and strategy in a dynamic environment. Collaborate cross-functionally to deliver impactful solutions that enha...

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Shape and drive product outcomes by managing a diverse range of responsibilities from product direction to technical problem-solving and stakeholder communication. Collaborate across teams and geograp...

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Pioneer a transformative approach to donation conversations, leading teams to enhance family engagement and authorization practices. Drive operational excellence while ensuring compassionate support f...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Transform the donation experience by leading strategic initiatives and high-performing teams dedicated to compassionate family engagement and operational excellence in organ and tissue donation proces...

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Take ownership of an AI-driven product, shaping strategy, roadmap, and execution for enterprise content insights. Collaborate with cross-functional teams to enhance adoption and value in regulated sec...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.