Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Account Director, Promotional Medical Education
$100K - $120K *
Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...
Reposted 1 week ago
$130K - $160K *
Drive product strategy and lifecycle management for diverse LED product families, collaborating with cross-functional teams to identify market needs, execute pricing strategies, and enhance product of...
Reposted 2 days ago
Director of Product Design, Engage
$195K - $208K *
Reimagine user experiences by leading design for core product features, ensuring seamless integration and customer delight. Collaborate across teams to enhance engagement and trust, shaping the future...
2 weeks ago
Executive Medical Director (Retina Program)
$350K - $398K *
Drive impactful clinical trials in ophthalmology with leadership in study design, execution, and biomarker strategy. Collaborate cross-functionally to ensure timely delivery and regulatory compliance...
Reposted 3 weeks ago
$170K - $180K *
Manage the product line of a flagship revenue integrity system, overseeing operations, feature development, and client communication to enhance product success while leading a dedicated team in a fast...
1 month ago
Director, Manufacturing Finance
$125K - $150K *
Join us as a strategic finance leader, driving performance and decision-making across manufacturing sites. Collaborate with cross-functional teams to enhance profitability, optimize capital, and devel...
3 weeks ago
Director, Manufacturing Finance
$125K - $150K *
Join a team that's driving financial performance across manufacturing sites. This role partners with leadership to enhance decision-making, optimize profitability, and ensure financial stewardship, wh...
3 weeks ago
Manager, Digital Customer Success
$110K - $130K *
Champion digital engagement by leading customer success initiatives. Manage a team to design scalable, tech-enabled strategies that enhance customer satisfaction, retention, and lifetime value through...
Reposted 2 weeks ago
Government Program Manager ILS2
$100K - $120K *
Pioneer operational excellence by leading integrated logistics and medical support for military operations. Drive program performance, manage teams, and ensure mission readiness across diverse environ...
3 weeks ago
Senior Manager, Integrated Intelligence
$85K - $105K *
Shape impactful insights through analytics, driving data-informed decisions for healthcare clients. Collaborate with cross-functional teams to enhance marketing performance and audience understanding...
Reposted 1 week ago
Implementation & Change Management Lead
$125K - $145K *
Lead the AirHub implementation, coordinating complex enterprise initiatives and ensuring operational readiness across cross-functional teams, from UAT to production rollouts, enhancing user support an...
Reposted 3 weeks ago
$155K - $233K *
Elevate organizational success by managing design and engineering teams, ensuring quality and profitability while driving innovation and resource planning to meet customer needs and exceed company goa...
5 days ago
Forward Deployed Product Manager
$120K - $145K *
Accelerate progress at transforming unstructured plan catalogs into structured data. Collaborate with teams to enhance analytical capabilities and ensure precise delivery of actionable insights for a...
Reposted 3 weeks ago
$170K - $180K *
Unlock potential by leading a diverse team of technical professionals to ensure timely project delivery and operational excellence. Drive collaboration, manage risks, and enhance project management pr...
Yesterday
$145K - $152K *
Champion program excellence by leading complex federal initiatives, managing multidisciplinary teams, and fostering strong stakeholder relationships to ensure successful delivery and client satisfacti...
2 weeks ago
$150K - $160K *
Lead the charge in managing multi-vendor coordination and cross-team delivery of patient-generated health data applications, ensuring alignment of technical execution with program goals to achieve imp...
1 month ago
Sr. Practice Manager -- Data Platforms
$150K - $190K *
Lead the charge in shaping data platform strategies and governance, driving innovative solutions and team development. Collaborate with partners to enhance AI readiness and ensure successful technical...
1 week ago
Senior Director, Engineering - Proactive Offense
$315K - $370K *
Join a team that's redefining offensive security by leading engineering efforts to transform research into scalable, customer-facing products. Drive strategy, execution, and innovation across multiple...
2 days ago
Manager, AI Governance Programs
$127K - $194K *
Unlock potential by leading AI governance initiatives to ensure security and compliance across Lenovo's AI projects. Collaborate with cross-functional teams to operationalize risk management and uphol...
3 weeks ago
Senior Manager, AI Advisory and Open Source Program Office
$200K - $250K *
Unlock the potential of Open Source and AI governance by leading a multidisciplinary team to ensure compliance, drive best practices, and foster innovation across the enterprise, while collaborating w...
Today
Delivery Manager - Decypher Corporate
$135K - $150K *
Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...
6 days ago
Principal Group Product Manager- AL Labs
$170K - $243K *
Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...
1 week ago
Manager II GBD Special Programs-Operation Clinical Advisor Teams
$88K - $105K *
Elevate care management operations by leading clinical teams, ensuring quality oversight, and driving community integration initiatives for children and youth. Collaborate cross-functionally to enhanc...
Today
Manager II GBD Special Programs-Operation Clinical Advisor Teams
$88K - $105K *
Lead the charge in managing care management operations for youth, ensuring quality oversight, compliance, and community integration while driving program effectiveness and team development across clin...
Today
$160K - $200K *
Shape the future of platform capabilities by leading strategy and execution for data, AI, and user experience initiatives. Collaborate with cross-functional teams to drive innovation and enhance custo...
Today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.